JEM cover acquired by Luis Marrero, Chad Steele, and the Morphology and Imaging Core Laboratory. The top image shows dectin-1 -glucan expression (red) on the surface of an alveolar macrophage at the initiation of phagocytosis of the cyst form of Pneumocystis Carinii (labeled with fluorescein isothiocyanate, green). Blue indicates the DNA-specific stain Dapi. In the bottom image, a pseudocolor rendering demonstrates colocalization (green-yellow) of dectin-1 in the phagocytic cup and the P. Carinii cell wall. See related article by Steele et al. by clicking on the image above.