Resource and Data Sharing
Tissue samples obtained from study animals at the time of necropsy will be available. The comprehensive data-set will include animal health records and laboratory data from blood, cell, tissue, biological fluid samples collected throughout the course of the study. Thus, spin-off pilot projects using nonhuman primate tissues or data obtained but not used for the main research components will be feasible. Access to this data set will be available to intra- and extramural investigators interested in expanding the CARC’s focus of research.
Requests for access to biological samples obtained from our animals will be accepted from researchers not affiliated with this CARC. These requests will be evaluated by the Intramural Center Committee (ICC) based on the following guidelines: 1) executing the request does not interfere with the primary studies presented in this application; 2) IACUC approval is obtained; 3) the collected biological sample is scientifically justified to have potential benefit to understanding the impact of alcohol on SIV disease prevention, progression or treatment; 4) costs of obtaining the biological sample are agreed upon based on relatedness to the current proposal. Necropsy samples are available from study animals without IACUC approval and can be provided upon request. Because of cost and storage limitations, tissues not directly needed for existing projects are not collected. In order to maximize the possibilities of providing necessary tissues to other investigators, advanced notice will be sent to those investigators that have contacted the LSUHSC CARC requesting access to tissues when the time of necropsy is determined. Processing, shipping, and handling of the requested samples will be covered by the requesting individual. Biological material transfer requests will be approved based on submission of a material transfer request, to be reviewed by the Office of Technology Management of the LSUHSC-NO. Priority will be given to those projects that have greater promise to develop new areas of investigation or to synergize with existing research interests of the CARC. This will be evaluated by the ICC. Requests for access to existing clinical data or biological samples from the translational studies will also be considered by the ICC. A formal request delineating the data-sharing agreement will include the following in addition to the guidelines described above: a commitment to using the data only for research purposes and not to identify any individual participant.
For both animal and human data sharing,(a) assurance that data will be used in accordance with the NIH Public Access Policy regarding submission to peer-reviewed journals and submission of the published manuscript to the digital archive of PubMed Central no later than 12 months after publication; (b) assurance that the original values within the data-set will not be altered in any way; (c) assurance that the data will be secure using appropriate computer technology and that the data will not be distributed to a third party; (d) assurance that the data will not be used for commercial purposes or to raise money by an individual or affiliated organization; and (e) acknowledgment that the CARC grant is the data resource in scientific publications; will be requested.
Researchers requesting access to data or biological specimens will obtain access upon the executing the data-sharing agreement or an appropriate material transfer agreement, as applicable, by the requesting investigator and an authorized representative of the recipient institution. All requests will be processed by the LSUHSC Office of Technology Management in accordance with LSUHSC’s policy on material transfer. Final research data will be released for sharing at the time of acceptance for publication of the main findings by CARC investigators.
All requests for resource or data sharing should be sent to Betsy Giaimo at firstname.lastname@example.org.