Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization. Gama V, Gomez JA, Mayo LD, Jackson MW, Danielpour D, Song K, Haas AL, Laughlin MJ, Matsuyama. S. Cell Death Differ. 16:758-769. (2009)

Cho KI, Yi H, Desai R, Hand AR, Haas AL, Ferreira PA.RANBP2 is an allosteric activator of the conventional kinesin-1 motor protein, KIF5B, in a minimal cell-free system. EMBO Rep. 10:480-486. (2009)

Haas AL. Linear polyubiquitylation: the missing link in NF-kappaB signaling. Nat Cell Biol. 11:116-118.(2009)

Giannakopoulos NV, Arutyunova E, Lai C, Lenschow DJ, Haas AL, Virgin HW. ISG15 Arg151 and the ISG15-conjugating enzyme UbE1L are important for innate immune control of Sindbis virus. J Virol. 83:1602-1610. (2009)

Haas AL. Wilkinson KD. DeTEKting ubiquitination of APC/C substrates. Cell. 133:570-572. (2008)

Haas AL. Structural insights into early events in the conjugation of ubiquitin and ubiquitin-like proteins. Mol Cell. 27:174-175. (2007)

Sorensen CM, Rempel LA, Nelson SR, Francis BR, Perry DJ, Lewis RV, Haas AL, Hansen TR. The hinge region between two ubiquitin-like domains destabilizes recombinant ISG15 in solution. Biochemistry 46:772-780. (2007)

Melner MH, Haas AL, Klein JM, Brash AR, Boeglin WE, Nagdas SK, Winfrey VP, Olson GE. Demonstration of Ubiquitin Thiolester Formation of UBE2Q2 (UBCi), a Novel Ubiquitin Conjugating Enzyme with Implantation Site-Specific Expression. Biol. Reproduction 75:395-406. (2006)

Tokgoz Z, Bohnsack RN, Haas AL. Pleiotropic effects of ATP•Mg²⁺ binding in the catalytic cycle of ubiquitin-activating enzyme. J Biol Chem. 281:14729-14737. (2006)

Haas, AL. ISG15-dependent regulation, in Protein Degradation, J. Mayer, A. Ciechanover, and R. Rechsteiner, eds., Wiley-VCH Verlag, Weinheim, Germany, 5:103-131. (2006)

Chen Y, Dai X, Haas AL, Wen R, Wang D. Proteasome-dependent down-regulation of activated Stat5A in the nucleus. Blood 108:566-574. (2006) 

Desai SD, Haas AL, Wood LM, Tsai YC, Pestka S, Rubin EH, Saleem A, Nur-E-Kamal A, Liu LF. Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway. Cancer Res. 66:921-921. (2006)

Gama V, Yoshida T, Gomez JA, Basile DP, Mayo LD, Haas AL, Matsuyama S. Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis. Exp Cell Res. 312:488-488. (2006)

Shang F, Deng G, Liu Q, Guo W, Haas AL, Crosas B, Finley D, Taylor A. Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation. J Biol Chem. 280:20365-20365. (2005)

Narasimhan, J., Wang, M., Klein, J.M., Haas, AL*, and Kim, J.-J.P.*, Crystal structure of the interferon-induced ubiquitin-like protein ISG15. J. Biol. Chem. 280:27356-27365 (2005) (Cited by the Faculty of 1000; *corresponding authors) Reddy ST, Kumar SN, Haas AL, Dahms NM. Biochemical and functional properties of the full-length cation-dependent mannose 6-phosphate receptor expressed in Pichia pastoris. Biochem Biophys Res Commun. 309:643-651. (2003)

Kotamraju S, Tampo Y, Keszler A, Chitambar CR, Joseph J, Haas AL, Kalyanaraman B. N. Nitric oxide inhibits H2O2-induced transferrin receptor-dependent apoptosis in endothelial cells: Role of ubiquitin-proteasome pathway. Proc Natl Acad Sci U S A. 100:10653-8. (2003)

Bohnsack RN, Haas AL. Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer. J Biol Chem.278(29):26823-26830. (2003)

Siepmann TJ, Bohnsack RN, Tokgoz Z, Baboshina OV, Haas AL. Protein interactions within the N-end rule ubiquitin ligation pathway. J Biol Chem. 278:9448-9457. (2003)

Badciong JC, Haas AL. MdmX is a RING finger ubiquitin ligase capable of synergistically enhancing Mdm2 ubiquitination. J Biol Chem. 277:49668-49675. (2002)

Wendelberger KJ, Burke R, Haas AL, Harenwattananon M, Simpson D. Identifying Opportunities for Vertical Integration of Biochemistry and Clinical Medicine. Adv Health Sci Educ Theory Pract. 3:157-164. (1998)

Balakirev MY, Jaquinod M, Haas AL, Chroboczek J. Deubiquitinating function of adenovirus proteinase. J Virol. 76:6323-6331. (2002)

Hamerman JA, Hayashi F, Schroeder LA, Gygi SP, Haas AL, Hampson L, CoughlinP, Aebersold R, Aderem A. Serpin 2a is induced in activated macrophages and conjugates to a ubiquitin homolog. J Immunol. 168:2415-2423. (2002)

Pru JK, Austin KJ, Haas AL, Hansen TR. Pregnancy and interferon-tau upregulate gene expression of members of the 1-8 family in the bovine uterus. Biol Reprod. 65:1471-1480. (2001)

Lawson TG, Sweep ME, Schlax PE, Bohnsack RN, Haas AL. Kinetic analysis of the conjugation of ubiquitin to picornavirus 3C proteases catalyzed by the mammalian ubiquitin-protein ligase E3alpha. J Biol Chem. 276:39629-39637. (2001)

Baboshina OV, Crinelli R, Siepmann TJ, Haas AL. N-end rule specificity within the ubiquitin/proteasome pathway is not an affinity effect. J Biol Chem. 276:39428-39437. (2001)

Macdonald JM, Haas AL, London RE. Novel mechanism of surface catalysis of protein a dduct formation. NMR studies of the acetylation of ubiquitin. J Biol Chem. 275:31908-31913. (2000)

Kurtzman AL, Gregori L, Haas AL, Schechter N. Ubiquitination and degradation of the zebrafish paired-like homeobox protein VSX-1. J Neurochem, 75:48-55. (2000)

Wilkinson KD, Laleli-Sahin E, Urbauer J, Larsen CN, Shih GH, Haas AL, Walsh ST, Wand AJ. The binding site for UCH-L3 on ubiquitin: mutagenesis and NMR studies on the complex between ubiquitin and UCH-L3. J Mol Biol. 291:1067-1077. (1999)

Potter JL, Narasimhan J, Mende-Mueller L, Haas AL. Precursor processing of pro-ISG15/UCRP, an interferon-beta-induced ubiquitin-like protein. J Biol Chem. 274:25061-25068. (1999)

Macdonald JM, LeBlanc DA, Haas AL, London RE. An NMR analysis of the reaction of ubiquitin with [acetyl-1-13C]aspirin. Biochem Pharmacol. 57:1233-1244. (1999)

Obin M, Mesco E, Gong X, Haas AL, Joseph J, Taylor A. Neurite outgrowth in PC12 cells. Distinguishing the roles of ubiquitylation andubiquitin-dependent proteolysis. J Biol Chem. 274:11789-11795. (1999)