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KyungWon Huh, PhD Profile

KyungWon Huh , PhD
Assistant Professor

Department of Biochemistry & Molecular Biology
1901 Perdido Street, Box P7-2, Room 7114
New Orleans, LA 70112
504.568.2817
Office MEB 7114
khuh@lsuhsc.edu

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		Department of Biochemistry and Molecular Biology LSU School of Medicine 1901 Perdido Street Room 7101 New Orleans, LA 70112 (504) 568-4733

Biography:
Dr. Huh received her B.S. in Biology from Ewha Women’s University, in Seoul, South Korea and obtained her M.S. in Biology from California State University, San Bernardino in 1992 and in Biomedical Science from the University of Colorado Health Sciences Center in 1995. She completed her Ph.D. in Microbiology and Immunology at the University of Colorado Health Sciences Center in 2001. She completed her postdoctoral fellowship at Harvard Medical School and Brigham and Womens Hospital, MA.

Research interests
The mechanisms and functions of human papillomavirus (HPV) oncoproteins

Selected Publications

Waris G, Huh KW, Siddiqui A. Mitochondrially associated hepatitis B Virus X protein constitutively activates transcription factors STAT-3 and NFB via oxidative stress. Mol Cell Biol. 21, 7721-7730 (2001)

Rahmani Z*, Huh KW*, Lasher R, Siddiqui A. Hepatitis B virus X protein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potential. J Virol. 74, 2840-2846 (2000) (*equal contribution)

Huh KW and Siddiqui A. Characterization of HBx association with mitochondria. Mitochondrio 1, 349-359 (2002)

Munger K, Baldwin A, Edwards KM, Hayakawa H,Nguyen CL, Owens M, Grace M, Huh KW. Mechanisms of human papilloma virus-induced oncogenesis, J.Virol. 78., 11451-11460 (2004)

Huh KW, DeMasi J, Ogawa H, Nakatani Y, Howley PM, Münger K. Association of the human papillomavirus type 16 E7 oncoprotein with the 600 kDa retinoblastoma protein associated factor, p600. Proc. Natl. Acad. Sci. USA 102, 11492-11497 (2005)

DeMasi J, Huh KW, Nakatani Y, Munger K, Howley PM. Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding. Proc. Natl. Acad. Sci. USA 102. 11486-11491 (2005)

Baldwin A, Huh KW, Munger K. The HPV E7 oncoprotein dysregulates steroid receptor coactivator-1 localization and function. J.Virol. 80, 6669-6677 (2006)

Huh KW, Zhou X, Hayakawa H, Cho JY, Libermann T.A., Jin J, Harper W. J., and Munger K. Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor. J. Virol. 81,9737-9747 (2007)

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