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Molecular Characterization of the Tumor-Suppressive Function of Nischarin in Breast Cancer. Somesh Baranwal, Yanfang Wang, Rajamani Rathinam, Jason Lee, Lianjin Jin, Robin McGoey, Yuliya Pylayeva, Filippo Giancotti, Gerard C. Blobe and Alahari SK. JNCI J Natl Cancer Inst (2011) doi: 10.1093/jnci/djr350 First published online: September 14, 2011
Role of Rho GTPases and their regulators in cancer progression.Rathinam R, Berrier A, Alahari SK. Front Biosci. 2011 Jun 1;17:2561-71.PMID:21622195 [PubMed - in process] Related citations
Rho GTPase Effector Functions in Tumor Cell Invasion and Metastasis.Baranwal S, Alahari SK.Curr Drug Targets. 2011 Jul 1;12(8):1194-201.PMID:21561416[PubMed - in process]Related citations
Integrin subunits alpha5 and alpha6 regulate cell cycle by modulating the chk1 and Rb/E2F pathways to affect breast cancer metastasis. Yanfang Wang, Sylvia Shenouda, Somesh Baranwal, Rajamani Rathinam, Prachi Jain, Lili Bao, Siddhartha Hazari, Srikanta Dash and Alahari SK. Molecular Cancer, 2011 (IN PRESS).
Wood LM, Sankar S, Reed RE, Haas AL, Liu LF, McKinnon P, Desai SD.A Novel Role for ATM in Regulating Proteasome-Mediated Protein Degradation through Suppression of the ISG15 Conjugation Pathway.PLoS One. 2011 Jan 26;6(1):e16422.PMID: 21298066
Breast cancer stem cells: A new challenge for breast cancer treatment Jain P, Alahari SK Frontiers in Bioscience 16, 1824-1832, (1 January, 2011)
Integrin mediated function of Rab GTPases in cancer progression Subramani D and Alahari SK Molecular Cancer 2010, 9:312 (9 December 2010)
Geng CD, Vedeckis WV. Use of Recombinant Cell-Permeable Small Peptides To Modulate Glucocorticoid Sensitivity of Acute Lymphoblastic Leukemia Cells.Biochemistry. Sep 27; (2010) Open PDF of this article
Regulating the regulator: Rsp5 ubiquitinates the proteasome. Haas AL. Mol Cell. 5:623-624. (2010)
Local IGF-1 isoform protects cardiomyocytes from hypertrophic and oxidative stresses via SirT1 activity.Vinciguerra M, Santini MP, Claycomb WC, Ladurner AG, Rosenthal N.Aging (Albany NY). 2009 Dec 10;2(1):43-62.PMID: 20228935 Free PMC Article Free text
M Li, C Chen, DR Davies, and TK Chiu. An Induced-Fit Mechanism for Prolyl Endopeptidase. J.Biol.Chem. (May 5, 2010 IN PRESS).
Structural biology: Transformative encounters.Schulman BA, Haas AL. Nature. 463:889-890. (2010)
Important role of integrins in the cancer biology.Rathinam R, Alahari SK.Cancer Metastasis Rev. Jan 30 .(2010)
ATP hydrolysis in Eg5 kinesin involves a catalytic two-water mechanism. Parke CL, Wojcik EJ, Kim, S., Worthylake DK.J Biol Chem. Dec 15 (2010). *Paper of the Week*
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Gama V, Gomez JA, Mayo LD, Jackson MW, Danielpour D, Song K, Haas AL, Laughlin MJ, Matsuyama. Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization. S. Cell Death Differ. 16:758-769. (2009)
RANBP2 is an allosteric activator of the conventional kinesin-1 motor protein, KIF5B, in a minimal cell-free system. Cho KI, Yi H, Desai R, Hand AR, Haas AL, Ferreira PA. EMBO Rep. 10(5):480-486. (2009)
Linear polyubiquitylation: the missing link in NF-kappaB signalling. Haas AL. Nat Cell Biol.11:116-118.(2009)0Suppression of tumorigenicity 14 (ST14) gene is a target for miR-27b, and the inhibitory effect of ST14 on cell growth is independent of miR-27b regulation. Wang, Y., Rathinam. R., Walch, A., and Alahari, SK. Journal of Biological Chemistry Jun 22. (2009)
Stromal cells and integrins: conforming to the needs of the tumor microenvironment.Alphonso A, Alahari SK.Neoplasia.Dec;11(12):1264-71. (2009)
MicroRNA function in cancer; Oncogene or a tumor suppressor. Shenouda, S.K. and Alahari S K Cancer and Metastasis reviews. (In Press) (2009)
miRNA control of tumor cell invasion and metastasis.Baranwal S, Alahari SK. Int J Cancer. Oct 29. (2010)
ST14 (suppression of tumorigenicity 14) gene is a target for miR-27b, and the inhibitory effect of ST14 on cell growth is independent of miR-27b regulation.Wang Y, Rathinam R, Walch A, Alahari SK.J Biol Chem. Aug 21;284(34):23094-106. Jun 22. (2009)
Molecular mechanisms controlling E-cadherin expression in breast cancer. Baranwal, S and Alahari, SK. Biochemical and Biophysical Research Communications 384: 6-11 Apr 18. (2009)
Regulation of ROCKII by localization to membrane compartments and binding to DynaminI. Tumusiime S, Rana MK, Kher SS, Kurella VB, Williams KA, Guidry JJ, Worthylake DK, Worthylake RA.Biochem Biophys Res Commun. 2009 Apr 10;381(3):393-6. Feb 15. (2009)
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NSC 622124 Inhibits Human Eg5 and Other Kinesins via Interaction with the Conserved Microtubule-Binding Site (dagger). Learman SS, Kim CD, Stevens NS, Kim S, Wojcik EJ, Walker RA. Biochemistry. Mar 3;48(8):1754-1762. (2009)
Heme oxygenase-1 inhibits pro-oxidant induced hypertrophy in HL-1 cardiomyocytes. Brunt KR, Tsuji MR, Lai JH, Kinobe RT, Durante W, Claycomb WC, Ward CA, Melo LG. Exp Biol Med (Maywood)May;234(5):582-94. Feb 25.(2009)
The Drosophila modigliani (moi) gene encodes a HOAP-interacting protein required for telomere protection. Raffa GD, Siriaco G, Cugusi S, Ciapponi L, Cenci G, Wojcik E, Gatti M.Proc Natl Acad Sci U S A Feb 17;106(7):2271-6. Jan 30. (2009)
Linear polyubiquitylation: the missing link in NF-kappaB signalling. Haas AL. Nat Cell Biol. Feb;11(2):116-8.(2009)
ISG15 Arg151 and the ISG15-conjugating enzyme UbE1L are important for innate immune control of Sindbis virus. Giannakopoulos NV, Arutyunova E, Lai C, Lenschow DJ, Haas AL, Virgin HW. J Virol. Feb;83(4):1602-10. Dec 10.(2009) |
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