Publications

 

Semprun-Prieto LC, Sukhanov S, Yoshida T, Rezk BM, Gonzalez-Villalobos RA,Vaughn C, Michael Tabony A, Delafontaine P. Angiotensin II induced cataboliceffect and muscle atrophy are redox dependent. Biochem Biophys Res Commun. 2011Jun 3;409(2):217-21. Epub 2011 May 6. PubMed PMID: 21570954; PubMed CentralPMCID: PMC3109128. 

Duvernay MT, Wang H, Dong C, Guidry JJ, Sackett DL, Wu G. Alpha2B-adrenergicreceptor interaction with tubulin controls its transport from the endoplasmicreticulum to the cell surface. J Biol Chem. 2011 Apr 22;286(16):14080-9. Epub

2011 Feb 28. PubMed PMID: 21357695; PubMed Central PMCID: PMC3077609

Shai SY, Sukhanov S, Higashi Y, Vaughn C, Rosen CJ, Delafontaine P. Low circulating insulin-like growth factor I increases atherosclerosis in ApoE-deficient mice. Am J Physiol Heart Circ Physiol. 2011 May;300(5):H1898-906. Epub 2011 Feb 18. PubMed PMID: 21335474; PubMed Central PMCID: PMC3094094. 

Duvernay MT, Wang H, Dong C, Guidry JJ, Sackett DL, Wu G. Alpha2B-adrenergic receptor interaction with tubulin controls its transport from the endoplasmic reticulum to the cell surface. J Biol Chem. 2011 Apr 22;286(16):14080-9. Epub 2011 Feb 28. PubMed PMID: 21357695; PubMed Central PMCID: PMC3077609. 

Xu P, Sriramula S, Lazartigues E. ACE2/ANG-(1-7)/Mas pathway in the brain: the axis of good. Am J Physiol Regul Integr Comp Physiol. 2011 Apr;300(4):R804-17. Epub 2010 Dec 22. Review. PubMed PMID: 21178125; PubMed Central PMCID: PMC3075080. 

Winsauer PJ, Molina PE, Amedee AM, Filipeanu CM, McGoey RR, Troxclair DA, Walker EM, Birke LL, Stouwe CV, Howard JM, Leonard ST, Moerschbaecher JM, Lewis PB. Tolerance to chronic delta-9-tetrahydrocannabinol (Δ⁹-THC) in rhesus macaques infected with simian immunodeficiency virus. Exp Clin Psychopharmacol. 2011 Apr;19(2):154-72. PubMed PMID: 21463073; PMCID: PMC3140653. 

Krowicki ZK, Kapusta DR. Microinjection of glycine into the hypothalamic paraventricular nucleus produces diuresis, natriuresis, and inhibition of central sympathetic outflow. J Pharmacol Exp Ther. 2011 Apr;337(1):247-55. Epub 2011 Jan 13. PubMed PMID: 21233196; PubMed Central PMCID: PMC3063742. 

Lord K, Moll D, Lindsey JK, Mahne S, Raman G, Dugas T, Cormier S, Troxlair D, Lomnicki S, Dellinger B, Varner K. Environmentally persistent free radicals decrease cardiac function before and after ischemia/reperfusion injury in vivo. J Recept Signal Transduct Res. 2011 Apr;31(2):157-67. PubMed PMID: 21385100, PMID: PMC3152960. 

Bivona BJ, Park S, Harrison-Bernard LM. Glomerular filtration rate determinations in conscious type II diabetic mice. Am J Physiol Renal Physiol. 2011 Mar;300(3):F618-25. Epub 2010 Dec 8. PubMed PMID: 21147841; PubMed Central PMCID: PMC3064143. 

Hans CP, Feng Y, Naura AS, Troxclair D, Zerfaoui M, Siddiqui D, Jihang J, Kim H, Kaye AD, Matrougui K, Lazartigues E, Boulares AH. Opposing roles of PARP-1 in MMP-9 and TIMP-2 expression and mast cell degranulation in dyslipidemic dilated cardiomyopathy. Cardiovasc Pathol. 2011 Mar-Apr;20(2):e57-68. Epub 2010 May 7. PubMed PMID: 20434371, NIHMS191082. 

Breslin JW. ROCK and cAMP promote lymphatic endothelial cell barrier integrity and modulate histamine and thrombin-induced barrier dysfunction. Lymphat Res Biol. 2011 Mar;9(1):3-11. PubMed PMID: 21417762; PubMed Central PMCID: PMC3060730. 

Filipeanu CM, de Vries R, Danser AH, Kapusta DR. Modulation of α(2C) adrenergic receptor temperature-sensitive trafficking by HSP90. Biochim Biophys Acta. 2011 Feb;1813(2):346-57. Epub 2010 Dec 9. PubMed PMID: 21145921, PMCID: PMC3148834. 

Lightell DJ Jr, Moss SC, Woods TC. Loss of canonical insulin signaling accelerates vascular smooth muscle cell proliferation and migration through changes in p27Kip1 regulation. Endocrinology. 2011 Feb;152(2):651-8. Epub 2010 Dec 29. PubMed PMID: 21190963; PubMed Central PMCID: PMC3037159. 

Wainford RD, Kapusta DR. Hypothalamic paraventricular nucleus G alpha q subunit protein pathways mediate vasopressin dysregulation and fluid retention in salt-sensitive rats. Endocrinology. 2010 Nov;151(11):5403-14. Epub 2010 Sep 22. PubMed PMID: 20861238; PubMed Central PMCID: PMC2954710. 

Shai SY, Sukhanov S, Higashi Y, Vaughn C, Kelly J, Delafontaine P. Smooth muscle cell-specific insulin-like growth factor-1 overexpression in Apoe-/- mice does not alter atherosclerotic plaque burden but increases features of plaque stability. Arterioscler Thromb Vasc Biol. 2010 Oct;30(10):1916-24. Epub 2010 Jul 29. PubMed PMID: 20671230; PubMed Central PMCID: PMC2940990.  

Souza-Smith FM, Kurtz KM, Molina PE, Breslin JW. Adaptation of mesenteric collecting lymphatic pump function following acute alcohol intoxication. Microcirculation. 2010 Oct;17(7):514-24. doi: 10.1111/j.1549-8719.2010.00050.x. PubMed PMID: 21040117; PubMed Central PMCID: PMC3057893. 

Zerfaoui M, Errami Y, Naura AS, Suzuki Y, Kim H, Ju J, Liu T, Hans CP, Kim JG, Abd Elmageed ZY, Koochekpour S, Catling A, Boulares AH. Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation. J Immunol. 2010 Aug 1;185(3):1894-902. Epub 2010 Jul 7. PubMed PMID: 20610652; PubMed Central PMCID:PMC2910824. 

Lazartigues E. Inflammation and neurogenic hypertension: a new role for the circumventricular organs? Circ Res. 2010 Jul 23;107(2):166-7. PubMed PMID: 20651292; PubMed Central PMCID: PMC2932473. 

Lord KC, Shenouda SK, McIlwain E, Charalampidis D, Lucchesi PA, Varner KJ. Oxidative stress contributes to methamphetamine-induced left ventricular dysfunction. Cardiovasc Res. 2010 Jul 1;87(1):111-8. Epub 2010 Feb 5. PubMed PMID: 20139112; PubMed Central PMCID: PMC2883898. 

Pullikuth AK, Catling AD. Extracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP. Mol Cell Biol. 2010 Jul;30(13):3233-48. Epub 2010 May 3. PubMed PMID: 20439493; PubMed Central PMCID: PMC2897570. 

Xia H, Lazartigues E. Angiotensin-converting enzyme 2: central regulator for cardiovascular function. Curr Hypertens Rep. 2010 Jun;12(3):170-5. Review. PubMed PMID: 20424953; PubMed Central PMCID: PMC3093757.  

Feng Y, Xia H, Santos RA, Speth R, Lazartigues E. Angiotensin-converting enzyme 2: a new target for neurogenic hypertension. Exp Physiol. 2010 May;95(5):601-6. Epub 2009 Nov 18. PubMed PMID: 19923158; PubMed Central PMCID: PMC2858233. 

Moss SC, Lightell DJ Jr, Marx SO, Marks AR, Woods TC. Rapamycin regulates endothelial cell migration through regulation of the cyclin-dependent kinase inhibitor p27Kip1. J Biol Chem. 2010 Apr 16;285(16):11991-7. Epub 2010 Jan 22. PubMed PMID: 20097763; PubMed Central PMCID: PMC2852937. 

Higashi Y, Sukhanov S, Anwar A, Shai SY, Delafontaine P. IGF-1, oxidative stress and atheroprotection. Trends Endocrinol Metab. 2010 Apr;21(4):245-54. Epub 2010 Jan 12. Review. PubMed PMID: 20071192; PubMed Central PMCID: PMC2848911. 

Feng Y, Xia H, Cai Y, Halabi CM, Becker LK, Santos RA, Speth RC, Sigmund CD, Lazartigues E. Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertension. Circ Res. 2010 Feb 5;106(2):373-82. Epub 2009 Nov 19. PubMed PMID: 19926873; PubMed Central PMCID: PMC2818798. 

Struckhoff AP, Vitko JR, Rana MK, Davis CT, Foderingham KE, Liu CH, Vanhoy-Rhodes L, Elliot S, Zhu Y, Burow M, Worthylake RA. Dynamic regulation of ROCK in tumor cells controls CXCR4-driven adhesion events. J Cell Sci. 2010 Feb 1;123(Pt 3):401-12. Epub 2010 Jan 5. PubMed PMID: 20053635; PubMed Central PMCID: PMC2816185. 

Park S, Bivona BJ, Kobori H, Seth DM, Chappell MC, Lazartigues E, Harrison-Bernard LM. Major role for ACE-independent intrarenal ANG II formation in type II diabetes. Am J Physiol Renal Physiol. 2010 Jan;298(1):F37-48. Epub 2009 Oct 21. PubMed PMID: 19846569; PubMed Central PMCID: PMC2806123. 

Breslin JW, Kurtz KM. Lymphatic endothelial cells adapt their barrier function in response to changes in shear stress. Lymphat Res Biol. 2009 Dec;7(4):229-37. PubMed PMID: 20143922; PubMed Central PMCID: PMC2883493. 

Bazan HA, Lu Y, Thoppil D, Fitzgerald TN, Hong S, Dardik A. Diminished omega-3 fatty acids are associated with carotid plaques from neurologically symptomatic patients: Implications for carotid interventions. Vascul Pharmacol. 2009 Nov-Dec;51(5-6):331-6. Epub 2009 Sep 4. PubMed PMID: 19733689; PubMed Central PMCID: PMC2786054. 

Hans CP, Feng Y, Naura AS, Zerfaoui M, Rezk BM, Xia H, Kaye AD, Matrougui K, Lazartigues E, Boulares AH. Protective effects of PARP-1 knockout on dyslipidemia-induced autonomic and vascular dysfunction in ApoE mice: effects on eNOS and oxidative stress. PLoS One. 2009 Oct 13;4(10):e7430. PubMed PMID: 19823587; PubMed Central PMCID: PMC2757717. 

Reed R, Potter B, Smith E, Jadhav R, Villalta P, Jo H, Rocic P. Redox-sensitive Akt and Src regulate coronary collateral growth in metabolic syndrome. Am J Physiol Heart Circ Physiol. 2009 Jun;296(6):H1811-21. Epub 2009 Apr 17. PubMed PMID: 19376806; PubMed Central PMCID: PMC2716105. 

Duvernay MT, Dong C, Zhang X, Robitaille M, Hébert TE, Wu G. A single conserved leucine residue on the first intracellular loop regulates ER export of G protein-coupled receptors. Traffic. 2009 May;10(5):552-66. Epub 2009 Feb 11. PubMed PMID: 19220814; PubMed Central PMCID: PMC2852481. 

Bindom SM, Lazartigues E. The sweeter side of ACE2: physiological evidence for a role in diabetes. Mol Cell Endocrinol. 2009 Apr 29;302(2):193-202. Epub 2008 Oct 1. Review. PubMed PMID: 18948167; PubMed Central PMCID: PMC2676688. 

Tumusiime S, Rana MK, Kher SS, Kurella VB, Williams KA, Guidry JJ, Worthylake DK, Worthylake RA. Regulation of ROCKII by localization to membrane compartments and binding to DynaminI. Biochem Biophys Res Commun. 2009 Apr 10;381(3):393-6. Epub 2009 Feb 15. PubMed PMID: 19222995; PubMed Central PMCID: PMC2671801.

Hans CP, Zerfaoui M, Naura AS, Troxclair D, Strong JP, Matrougui K, Boulares AH. Thieno[2,3-c]isoquinolin-5-one, a potent poly(ADP-ribose) polymerase inhibitor, promotes atherosclerotic plaque regression in high-fat diet-fed apolipoprotein E-deficient mice: effects on inflammatory markers and lipid content. J Pharmacol Exp Ther. 2009 Apr;329(1):150-8. Epub 2009 Jan 5. PubMed PMID: 19124646; PubMed Central PMCID: PMC2670599. 

Shenouda SK, Varner KJ, Carvalho F, Lucchesi PA. Metabolites of MDMA induce oxidative stress and contractile dysfunction in adult rat left ventricular myocytes. Cardiovasc Toxicol. 2009 Mar;9(1):30-8. Epub 2009 Mar 31. PubMed PMID: 19333788; PubMed Central PMCID: PMC2859611. 

Wainford RD, Kapusta DR. Chronic high-NaCl intake prolongs the cardiorenal responses to central N/OFQ and produces regional changes in the endogenous brain NOP receptor system. Am J Physiol Regul Integr Comp Physiol. 2009 Feb;296(2):R280-8. Epub 2008 Nov 5. PubMed PMID: 18987291; PubMed Central PMCID: PMC2643980. 

Naura AS, Datta R, Hans CP, Zerfaoui M, Rezk BM, Errami Y, Oumouna M, Matrougui K, Boulares AH. Reciprocal regulation of iNOS and PARP-1 during allergen-induced eosinophilia. Eur Respir J. 2009 Feb;33(2):252-62. Epub 2008 Oct 1. PubMed PMID: 18829681. 

Xia H, Feng Y, Obr TD, Hickman PJ, Lazartigues E. Angiotensin II type 1 receptor-mediated reduction of angiotensin-converting enzyme 2 activity in the brain impairs baroreflex function in hypertensive mice. Hypertension. 2009 Feb;53(2):210-6. Epub 2009 Jan 5. PubMed PMID: 19124678; PubMed Central PMCID: PMC2695598. 

Moss SC, Lightell D Jr, Deichmann RE Jr, Woods TC. Sera from patients with diabetes do not alter the effect of mammalian target of rapamycin inhibition on smooth muscle cell proliferation. J Cardiovasc Pharmacol. 2009 Jan;53(1):86-9. PubMed PMID: 19129735; PubMed Central PMCID: PMC2891793. 

Xia H, Lazartigues E. Angiotensin-converting enzyme 2 in the brain: properties and future directions. J Neurochem. 2008 Dec;107(6):1482-94. Epub 2008 Nov 5. Review. PubMed PMID: 19014390; PubMed Central PMCID: PMC2667944. 

Park S, Bivona BJ, Feng Y, Lazartigues E, Harrison-Bernard LM. Intact renal afferent arteriolar autoregulatory responsiveness in db/db mice. Am J Physiol Renal Physiol. 2008 Nov;295(5):F1504-11. Epub 2008 Aug 27. PubMed PMID: 18753291; PubMed Central PMCID: PMC2584903. 

Yu B, Becnel J, Zerfaoui M, Rohatgi R, Boulares AH, Nichols CD. Serotonin 5-hydroxytryptamine(2A) receptor activation suppresses tumor necrosis factor-alpha-induced inflammation with extraordinary potency. J Pharmacol Exp Ther. 2008 Nov;327(2):316-23. Epub 2008 Aug 15. PubMed PMID: 18708586. 

Shenouda SK, Lord KC, McIlwain E, Lucchesi PA, Varner KJ. Ecstasy produces left ventricular dysfunction and oxidative stress in rats. Cardiovasc Res. 2008 Sep 1;79(4):662-70. Epub 2008 May 20. PubMed PMID: 18495670; PubMed Central PMCID: PMC2732062. 

Wainford RD, Kurtz K, Kapusta DR. Central G-alpha subunit protein-mediated control of cardiovascular function, urine output, and vasopressin secretion in conscious Sprague-Dawley rats. Am J Physiol Regul Integr Comp Physiol. 2008 Aug;295(2):R535-42. Epub 2008 Jun 4. PubMed PMID: 18525017; PubMed Central PMCID: PMC2519935. 

Blumer JB, Lord K, Saunders TL, Pacchioni A, Black C, Lazartigues E, Varner KJ, Gettys TW, Lanier SM. Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function. Endocrinology. 2008 Aug;149(8):3842-9. Epub 2008 May 1. PubMed PMID: 18450958; PubMed Central PMCID: PMC2488243.  

Guggilam A, Patel KP, Haque M, Ebenezer PJ, Kapusta DR, Francis J. Cytokine blockade attenuates sympathoexcitation in heart failure: cross-talk between nNOS, AT-1R and cytokines in the hypothalamic paraventricular nucleus. Eur J Heart Fail. 2008 Jul;10(7):625-34. Epub 2008 Jun 11. PubMed PMID: 18550427; PubMed Central PMCID: PMC2593148. 

Naura AS, Hans CP, Zerfaoui M, You D, Cormier SA, Oumouna M, Boulares AH. Post-allergen challenge inhibition of poly(ADP-ribose) polymerase harbors therapeutic potential for treatment of allergic airway inflammation. Clin Exp Allergy. 2008 May;38(5):839-46. Epub 2008 Feb 4. PubMed PMID: 18261157; PubMed Central PMCID: PMC2740645.

 Park S, Harrison-Bernard LM. Augmented renal vascular nNOS and renin protein expression in angiotensin type 1 receptor null mice. J Histochem Cytochem. 2008 Apr;56(4):401-14. Epub 2008 Jan 7. PubMed PMID: 18180383; PubMed Central PMCID: PMC2326101. 

Feng Y, Yue X, Xia H, Bindom SM, Hickman PJ, Filipeanu CM, Wu G, Lazartigues E. Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation. Circ Res. 2008 Mar 28;102(6):729-36. Epub 2008 Feb 7. PubMed PMID: 18258853; PubMed Central PMCID: PMC2279097. 

Zerfaoui M, Suzuki Y, Naura AS, Hans CP, Nichols C, Boulares AH. Nuclear translocation of p65 NF-kappaB is sufficient for VCAM-1, but not ICAM-1, expression in TNF-stimulated smooth muscle cells: Differential requirement for PARP-1 expression and interaction. Cell Signal. 2008 Jan;20(1):186-94. Epub 2007 Oct 12. PubMed PMID: 17993261; PubMed Central PMCID: PMC2278030. 

Hicks AR, Varner KJ. Cardiovascular responses elicited by intragastric administration of BDL and GHB. J Recept Signal Transduct Res. 2008;28(4):429-36. PubMed PMID: 18702013; PubMed Central PMCID: PMC2860846.

Saitoh S, Kiyooka T, Rocic P, Rogers PA, Zhang C, Swafford A, Dick GM, Viswanathan C, Park Y, Chilian WM. Redox-dependent coronary metabolic dilation. Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3720-5. Epub 2007 Oct 26. PubMed PMID: 17965288. 

Oumouna-Benachour K, Oumouna M, Zerfaoui M, Hans C, Fallon K, Boulares AH. Intrinsic resistance to apoptosis of colon epithelial cells is a potential determining factor in the susceptibility of the A/J mouse strain to dimethylhydrazine-induced colon tumorigenesis. Mol Carcinog. 2007 Dec;46(12):993-1002. PubMed PMID: 17538954. 

Pullikuth AK, Catling AD. Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective. Cell Signal. 2007 Aug;19(8):1621-32. Epub 2007 May 5. Review. PubMed PMID: 17553668; PubMed Central PMCID: PMC2233890. 

Park S, Bivona BJ, Harrison-Bernard LM. Compromised renal microvascular reactivity of angiotensin type 1 double null mice. Am J Physiol Renal Physiol. 2007 Jul;293(1):F60-7. Epub 2007 Apr 4. PubMed PMID: 17409281. 

Park ER, Eblen ST, Catling AD. MEK1 activation by PAK: a novel mechanism. Cell Signal. 2007 Jul;19(7):1488-96. Epub 2007 Jan 24. PubMed PMID: 17314031; PubMed Central PMCID: PMC2233889. 

Burmeister MA, Kapusta DR. Centrally administered nociceptin/orphanin FQ (N/OFQ) evokes bradycardia, hypotension, and diuresis in mice via activation of central N/OFQ peptide receptors. J Pharmacol Exp Ther. 2007 Jul;322(1):324-31. Epub 2007 Apr 23. PubMed PMID: 17452419. 

Rocic P, Kolz C, Reed R, Potter B, Chilian WM. Optimal reactive oxygen species concentration and p38 MAP kinase are required for coronary collateral growth. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2729-36. Epub 2007 Feb 16. PubMed PMID: 17308014. 

Rizzi A, Spagnolo B, Wainford RD, Fischetti C, Guerrini R, Marzola G, Baldisserotto A, Salvadori S, Regoli D, Kapusta DR, Calo G. In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptor. Peptides. 2007 Jun;28(6):1240-51. Epub 2007 May 6. PubMed PMID: 17532097; PubMed Central PMCID: PMC1975813. 

Oumouna-Benachour K, Hans CP, Suzuki Y, Naura A, Datta R, Belmadani S, Fallon K, Woods C, Boulares AH. Poly(ADP-ribose) polymerase inhibition reduces atherosclerotic plaque size and promotes factors of plaque stability in apolipoprotein E-deficient mice: effects on macrophage recruitment, nuclear factor-kappaB nuclear translocation, and foam cell death. Circulation. 2007 May 8;115(18):2442-50. Epub 2007 Apr 16. PubMed PMID: 17438151. Focardi

M, Dick GM, Picchi A, Zhang C, Chilian WM. Restoration of coronary endothelial function in obese Zucker rats by a low-carbohydrate diet. Am J Physiol Heart Circ Physiol. 2007 May;292(5):H2093-9. Epub 2007 Jan 12. PubMed PMID: 17220180. 

Hattan N, Chilian WM, Park F, Rocic P. Restoration of coronary collateral growth in the Zucker obese rat: impact of VEGF and ecSOD. Basic Res Cardiol. 2007 May;102(3):217-23. Epub 2007 Feb 27. PubMed PMID: 17323199. 

Dong C, Filipeanu CM, Duvernay MT, Wu G. Regulation of G protein-coupled receptor export trafficking. Biochim Biophys Acta. 2007 Apr;1768(4):853-70. Epub 2006 Sep 23. Review. PubMed PMID: 17074298; PubMed Central PMCID: PMC1885203.

Swafford AN Jr, Harrison-Bernard LM, Dick GM. Knockout mice reveal that the angiotensin II type 1B receptor links to smooth muscle contraction. Am J Hypertens. 2007 Mar;20(3):335-7. PubMed PMID: 17324748. 

Rogers PA, Chilian WM, Bratz IN, Bryan RM Jr, Dick GM. H2O2 activates redox- and 4-aminopyridine-sensitive Kv channels in coronary vascular smooth muscle. Am J Physiol Heart Circ Physiol. 2007 Mar;292(3):H1404-11. Epub 2006 Oct 27. PubMed PMID: 17071731. 

Lazartigues E, Feng Y, Lavoie JL. The two fACEs of the tissue renin-angiotensin systems: implication in cardiovascular diseases. Curr Pharm Des. 2007;13(12):1231-45. Review. PubMed PMID: 17504232. 

Simon V, Guidry J, Gettys TW, Tobin AB, Lanier SM. The proto-oncogene SET interacts with muscarinic receptors and attenuates receptor signaling. J Biol Chem. 2006 Dec 29;281(52):40310-20. Epub 2006 Oct 25. PubMed PMID: 17065150; PubMed Central PMCID: PMC2596874. 

Dong C, Wu G. Regulation of anterograde transport of alpha2-adrenergic receptors by the N termini at multiple intracellular compartments. J Biol Chem. 2006 Dec 15;281(50):38543-54. Epub 2006 Oct 12. PubMed PMID: 17038316; PubMed Central PMCID: PMC2648813. 

Dick GM, Katz PS, Farias M 3rd, Morris M, James J, Knudson JD, Tune JD. Resistin impairs endothelium-dependent dilation to bradykinin, but not acetylcholine, in the coronary circulation. Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H2997-3002. Epub 2006 Aug 11. PubMed PMID: 16905596. 

Saitoh S, Zhang C, Tune JD, Potter B, Kiyooka T, Rogers PA, Knudson JD, Dick GM, Swafford A, Chilian WM. Hydrogen peroxide: a feed-forward dilator that couples myocardial metabolism to coronary blood flow. Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2614-21. Epub 2006 Oct 5. PubMed PMID: 17023676. 

Rogers PA, Dick GM, Knudson JD, Focardi M, Bratz IN, Swafford AN Jr, Saitoh S, Tune JD, Chilian WM. H2O2-induced redox-sensitive coronary vasodilation is mediated by 4-aminopyridine-sensitive K+ channels. Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2473-82. Epub 2006 Jun 2. PubMed PMID: 16751285. 

Oumouna M, Datta R, Oumouna-Benachour K, Suzuki Y, Hans C, Matthews K, Fallon K, Boulares H. Poly(ADP-ribose) polymerase-1 inhibition prevents eosinophil recruitment by modulating Th2 cytokines in a murine model of allergic airway inflammation: a potential specific effect on IL-5. J Immunol. 2006 Nov 1;177(9):6489-96.

Erratum in: J Immunol. 2007 Oct 15;179(8):5604. Mustapha, Oumouna [corrected to Oumouna, Mustapha]. PubMed PMID: 17056581. Picchi A, Gao X, Belmadani S, Potter BJ, Focardi M, Chilian WM, Zhang C. Tumor necrosis factor-alpha induces endothelial dysfunction in the prediabetic metabolic syndrome. Circ Res. 2006 Jul 7;99(1):69-77. Epub 2006 Jun 1. PubMed PMID: 16741160. 

Filipeanu CM, Zhou F, Lam ML, Kerut KE, Claycomb WC, Wu G. Enhancement of the recycling and activation of beta-adrenergic receptor by Rab4 GTPase in cardiac myocytes. J Biol Chem. 2006 Apr 21;281(16):11097-103. Epub 2006 Feb 16. PubMed PMID: 16484224; PubMed Central PMCID: PMC2735442. 

Knudson JD, Rogers PA, Dincer UD, Bratz IN, Araiza AG, Dick GM, Tune JD. Coronary vasomotor reactivity to endothelin-1 in the prediabetic metabolic syndrome. Microcirculation. 2006 Apr-May;13(3):209-18. PubMed PMID: 16627363. 

Qian Z, Haessler M, Lemos JA, Arsenault JR, Aguirre JE, Gilbert JR, Bowler RP, Park F. Targeting vascular injury using Hantavirus-pseudotyped lentiviral vectors. Mol Ther. 2006 Apr;13(4):694-704. Epub 2006 Jan 23. PubMed PMID: 16431160. 

Boulares H, Zoltoski A, Kandan S, Akbulut T, Yakovlev A, Oumouna M. Correlation between decreased sensitivity of the Daudi lymphoma cells to VP-16-induced apoptosis and deficiency in DNAS1L3 expression. Biochem Biophys Res Commun. 2006 Mar 10;341(2):653-62. Epub 2006 Jan 17. PubMed PMID: 16427601. 

Zhang C, Xu X, Potter BJ, Wang W, Kuo L, Michael L, Bagby GJ, Chilian WM. TNF-alpha contributes to endothelial dysfunction in ischemia/reperfusion injury. Arterioscler Thromb Vasc Biol. 2006 Mar;26(3):475-80. Epub 2005 Dec 29. PubMed PMID: 16385082. 

Zhou F, Filipeanu CM, Duvernay MT, Wu G. Cell-surface targeting of alpha2-adrenergic receptors -- inhibition by a transport deficient mutant through dimerization. Cell Signal. 2006 Mar;18(3):318-27. Epub 2005 Jun 14. PubMed PMID: 15961277; PubMed Central PMCID: PMC2718052. 

Sato M, Cismowski MJ, Toyota E, Smrcka AV, Lucchesi PA, Chilian WM, Lanier SM. Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):797-802. Epub 2006 Jan 9. PubMed PMID: 16407149; PubMed Central PMCID: PMC1334649. 

Koshida R, Rocic P, Saito S, Kiyooka T, Zhang C, Chilian WM. Role of focal adhesion kinase in flow-induced dilation of coronary arterioles. Arterioscler Thromb Vasc Biol. 2005 Dec;25(12):2548-53. Epub 2005 Sep 29. PubMed PMID: 16195476. 

Duvernay MT, Filipeanu CM, Wu G. The regulatory mechanisms of export trafficking of G protein-coupled receptors. Cell Signal. 2005 Dec;17(12):1457-65. Review. PubMed PMID: 16014327. 

Knudson JD, Dincer UD, Dick GM, Shibata H, Akahane R, Saito M, Tune JD. Leptin resistance extends to the coronary vasculature in prediabetic dogs and provides a protective adaptation against endothelial dysfunction. Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1038-46. Epub 2005 May 13. PubMed PMID: 15894577. 

Bratz IN, Swafford AN Jr, Kanagy NL, Dick GM. Reduced functional expression of K(+) channels in vascular smooth muscle cells from rats made hypertensive with N{omega}-nitro-L-arginine. Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1284-90. Epub 2005 May 6. PubMed PMID: 15879481. 

Bratz IN, Dick GM, Partridge LD, Kanagy NL. Reduced molecular expression of K(+) channel proteins in vascular smooth muscle from rats made hypertensive with N{omega}-nitro-L-arginine. Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1277-83. Epub 2005 Mar 25. PubMed PMID: 15792990. 

Pullikuth A, McKinnon E, Schaeffer HJ, Catling AD. The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals. Mol Cell Biol. 2005 Jun;25(12):5119-33. PubMed PMID: 15923628; PubMed Central PMCID: PMC1140582. 

Swafford AN Jr, Bratz IN, Knudson JD, Rogers PA, Timmerman JM, Tune JD, Dick GM. C-reactive protein does not relax vascular smooth muscle: effects mediated by sodium azide in commercially available preparations. Am J Physiol Heart Circ Physiol. 2005 Apr;288(4):H1786-95. Epub 2004 Nov 24. PubMed PMID: 15563529. 

Filipeanu CM, Zhou F, Claycomb WC, Wu G. Regulation of the cell surface expression and function of angiotensin II type 1 receptor by Rab1-mediated endoplasmic reticulum-to-Golgi transport in cardiac myocytes. J Biol Chem. 2004 Sep 24;279(39):41077-84. Epub 2004 Jul 12. PubMed PMID: 15252015. 

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