Virendra Joshi, MD - LSUHSC School of Medicine

Administration	Basic Sciences	Clinical Sciences	Centers of Excellence
Admissions Alumni Affairs Community and Minority Health Education Computer Support Continuing Education Dean's Office Faculty & Institutional Affairs Fiscal Affairs Libraries Medical Education Research Student Affairs	Biochemistry & Molecular Biology Cell Biology & Anatomy Genetics Microbiology, Immunology & Parasitology Pharmacology Physiology	Anesthesiology Dermatology Family Medicine Internal Medicine Emergency Medicine Gastroenterology Physical Medicine & Rehabilitation Neurology Neurosurgery OB/GYN Ophthalmology Orthopaedics Otorhinolaryngology Pathology Pediatrics Psychiatry Radiology Surgery Urology	Alcohol and Drug Abuse Center Cardiovascular Center Center on Healthy Aging Center for Molecular and Human Genetics Epilepsy Center Eye Center Ernest N. Morial Asthma, Allergy, and Respiratory Disease Center Gene Therapy Program Low Vision Center Neurosciences Center The Research Institute For Children Stanley S. Scott Cancer Center

Faculty

Fellowship

Research

Alumni

Links

Curriculum

New Orleans

Department Title

	Virendra Joshi, MD Director , Endoscopy and Hepatobiliary Services Tulane University Hospital and Clinic 1430 Tulane Ave SL35 New Orleans, La 70112 504-988-5763 www.Tulane.edu
Degrees	1984 St. Xavier Senior Secondary School New Delhi, India 1988 M.B.B.S. University College of Medical Sciences and Affiliated hospitals New Delhi, India Board Certification: American Board of Internal Medicine: 1996 thru 2006 American Board of Gastroenterology and Hepatology: 1997 thru 2007 2008 thru 2018
Bio	*Residency/Internships/fellowships* 1989-1992: Residency in Radiology, New Delhi, India 1992-93: Internship in Internal Medicine, Johns Hopkins University School of Medicine and affiliated hospitals, Baltimore, Maryland 1993-95: Residency, Internal Medicine, University of Illinois at Chicago – Michael ReeseHospital, Chicago, Illinois 1995-96: Physician-Scientist at the Institute of Molecular Medicine, Department of Internal Medicine, Section of Gastroenterology, Hepatology and Nutrition, Medical college of Georgia, Augusta, Georgia 1996-98 : Fellowship, Department of Gastroenterology, Hepatology and Nutrition at the Medical College of Georgia, GeorgiaHealthSciencesUniversity, Augusta Georgia Faculty Appointments: June1998-Nov.2000: Senior Consultant, Gastroenterology and Hepatology, IndraprasthaApolloHospital, New Delhi, India Dec.2000-Dec.2001: Staff Physician Gastroenterology ,Ochsner Clinic and Research Foundation, New Orleans, La. Jan, 2002: Assistant Professor of Medicine, Section of Gastroenterology and Hepatology, TulaneUniversityMedicalSchool. Jan, 2002: Assistant Clinical Professor of Surgery, Department of Surgery, Tulane UniversityMedicalSchool Jan. 2002: Tulane Co-Director of Endoscopy – MedicalCenter of Louisiana at New Orleans, La Sep, 2004: Course Coordinator - Liver and Gastroenterology Pathophysiology Course, Tulane University School of Medicine July, 2005: Associate Professor of Medicine and Director, Hepatology in th e Section of Gastroenterology and Hepatology, Tulane University Health SciencesCenter. New Orleans, La. July 2005 Associate Clinical Professor of Surgery July 2006 Director , Endoscopy and Hepatobiliary Services
Research Interests	*Principal Investigator on the following studies:* A Non –Randomized Multicenter Study to Evaluate the pharmacokinetics and safety of Pegylated Interferon Alpha-2a and Copegus Combination Therapy after single and multiple doses in patients with Chronic Hepatitis C and moderate renal impairment, severe renal impairment or end-stage renal disease undergoing hemodialysis. IRB Protocol #NP 17335. 2004 (Funding- Roche Pharmaceuticals) Value of Grant: $170,000 Apr 2004 – Nov 2006 A Randomized Controlled Pilot Trial of Diet and Exercise Versus Diet and Exercise With Mucomyst and Trental for Treatment Of Non–Alcoholic Steatohepatitis (NASH)- 2004. Grant Support from GCRC NIH Grant #5M01RR05096-10. Value of Grant: $30,000 Duration: 2 years in progress *Randomised , Multicenter, Double Blinded Trial Evaluating Efficacy ( SVR) and Safety of 360ug induction Dosing of Pegasys in combination with Copegus Doses in Treatment –Naïve Patients with Chronic Hepatitis C Genotype 1 virus infection of high viral titer and baseline body weight greater than or equal to 85 kg Grant Value : $251,000 Nov ,2006 -current
Teaching Activities	· Course Coordinator: T-2 Mechanisms of Diseases; GI Pathophysiology Course: 2004- 2005 · Specialty Specific Mentor Program: 2004 and 2005: (Five T3 students) · T3 (Third Year) 6 lectures/Academic year: 2002-2005 · Clinical Pharmacology T2 student course: Drug induced liver disease (1 lecture/year) (Organized by Dr. Juan Lertora: Director, Clinical Pharmacology) · Tulane GI Consult Service (5-6 months/year): Education of Students, Residents and Fellows on the Service · Student Research: Supervisor along with Drs. Curiel and Monsourzadeh of 4^th year student Ms. Julie Lee (Gastroenterology elective to learn basic research techniques). She was awarded the Akdamar Award by Gastroenterology Section for outstanding GI student for the year. · GI Core Lectures to Residents – 2 per Academic Year: 2002-2005 · GI Core Lectures to GI Fellows – 6 per Academic Year: 2002-2005 · Teaching of Advanced Endoscopic Procedures 3^rd year fellows: Endoscopic Retrograde Cholangiopancreatography (diagnostic and therapeutic) Endoscopic Ultrasound Endoscopic Mucosal Resection
Committees & Administrative Responsibilities	·Chair, Tulane-MCLNO Committee on Guidelines for Albumin use in ICU. Endoscopy Committee at MCLNO (Monthly Meetings)
Selected Publications	Joshi V, Awad K, Fermin C, Dash S. Antiviral properties of Pegylated versus Non-Pegylated Interferon alpha-2b against Hepatitis C in cell culture.. DDW New Orleans, May, 2004 ( Poster presentation). Curiel T, Landry S, Morris C, Joshi V, Alvarez X, Monsourzadeh M.Targeting HCV NS3-NS4A to dendritic cells (DC) via DC binding peptides induces potent T cell immunity in vivo. Oral Presentation. Keystone Symposium 2004, Colorado.( Oral Presentation) Russo M, Segal SH, Ghalib R, Joshi V, Detwiler R, Andreoni K, Shrestha R. A multicenter randomised trial of Pegylated Interferon alpha-2b monotherapy (Intron–A) in patients with chronic Hepatitis C and end stage kidney disease. Poster Presentation. AASLD 2004, Boston ( Poster presentation) Use of Polyflex Stent in conjunction with Inflaximab for refractory Crohns Esophageal Stricture: Jacob M Fegans, Farshad Aduli, David Victor, Virendra Joshi Section of Gastroenterology , Tulane University Health Sciences Center, New Orleans , LA A Dual Forceps –Snare Technique for Removal of a covered Metal Stent Charles Chaya,MD, Khan Lee, MD , Virendra Joshi , MD,Gastroenterology UTMB , Galveston , TX and Gastroenterology , Tulane , New Orleans Dash S, Haque S, Joshi V, Prabhu R, Hazari S, Fermin C, Garry R. HCV-hepatocellular carcinoma: new findings and hope for effective treatment. Microscopy Research and Technique 2005 Nov; 68(3-4):130-48. Hazari S, Patil A, Joshi V, Sullivan DE, Fermin CD, Garry RF, Elliott RM, Dash S. Alpha interferon inhibits translation mediated by the internal ribosome entry site of six different hepatitis C virus genotypes. Journal of General Virology. 2005 Nov: 86 (Pt 11): 3047-53. Dash S, Prabhu R, Hazari S, Bastian F, Garry R, Zou W, Haque S, Joshi V, Regenstein FG, Thung SN. Interferons alpha, beta, gamma each inhibit hepatitis C virus replication at the level of internal ribosome entry site-mediated translation. Liver International. 2005 Jun; 25(3):580-94. *Russo MW, Ghalib R, Sigal S, Joshi V. Randomized trial of pegylated interferon alpha-2b monotherapy in haemodialysis patients with chronic hepatitis C. Nephrology, Dialysis, and Transplantation . 2006 Feb; 21(2):437-43.