|Allergy and Immunology
Physical Medicine and Rehablitation
|Prem Kumar||HLA-D Locus compatibility - Using early lymphocyte activation
signals application in cadaveric renal transplantation.
Cost of care and quality of life of allergic rhinitis patient receiving allergen immuno therapy.
The influence of Yoga on asthma and on neuropeptides and cytokines.
Increased ocular pressure and cataracts following inhaled and nasal steroids for asthma and rhinitis.
|Prakash N. Rao, Ph. D.||Preservation and reperfusion injury; characterization
and implications for clinical transplantation.
CD-69 and urinary glutathione-S-transferases (GST)
as markers of immune injury in clinical renal transplantation.
Vitamin carrier protein in cancer; implications for early detection and treatment (with particular emphasis on breast, liver and prostate cancers).
DNA vaccines for the treatment of prostate and mannary carcinomas.
Evaluation of techniques of pyschoneuroimmunology (PNI) in the treatment of breast cancer.
|J. Daniel Andress, M.D.||Dr. Andress is the Assistant Director of the LSU Arrthymia Service Current
research interests include drug studies and recent advances in defibrillator devices.
|Thomas D. Giles, M.D.||Dr. Giles is the Director of Cardiovascular Research. He is principal
investigator for a number of clinical trials focused upon heart failure, hypertension, and
angina. He has basic research interest in pathophysiologic mechanisms for development of
heart failure in diabetes and hypertension.
|Michael B. Givens, Ph.D.||Dr. Given is a pharmacologist working in the field of diabetes and heart
disease. He is currently investigating the effect of diabetes mellitus on bradykinin
metabolism and its effect on the coronary circulation. He is also collaborating with other
investigators on the role of the kinin system in the development of atherosclerosis in
both normal and diabetic vessels.
|D. Luke Glancy, M.D.||Dr. Glancy is the Chief of the Section of Cardiology, Medical Director of
Cardiology at the Medical Center of Louisiana in New Orleans and directs the
interventional cardiology program. He also has special interest in scalar
electrocardiography and congenital heart disease in adults. He directs several projects
studying chemical aspects of cardiovascular disease.
|Stanley S. Greenberg, Ph.D.||Dr. Greenberg works in the Cardiovascular research laboratory. He runs the
nitric oxide laboratory and has joint appointments in pharmacology and physiology, where
he has student teaching responsibilities.
|Frederick Helmcke, M.D.||Dr. Helmcke is the Director of the LSU Echocardiography laboratory,
implementing myocardial contrast Echocardiography and investigating 3 and 4 dimensional
echocardiographic techniques. Hes also active in LSUs Telemedicine Program.
|Gary E. Sander, M.D., Ph.D.||Dr. Sander functions as principal investigator for several clinical
research studies and serves as editor for the Louisiana Chapter ACC Newsletter.
|Akbar Shah, M.D.||Dr. Shah is Associate Director of the LSU Cardiology Fellowship Program.
Together with Dr. Glancey, he directs several clinical research projects.
|Parakat Vijayagopal, Ph. D.||Dr. Vijayagopal is primarily involved with cardiovascular research and his
main interests are in the mechanisms of atherogenesis and in proteoglycan metabolism by
|Summary of research interests: Cardiovascular research includes both basic and clinical science activities. The basic cardiovascular research interest include investigations into the pathogenesis of diabetic cardiovascular disease and atherosclerosis. Experiments models include animal and cellular preparations and extend from whole animal experiments to in vitro pharmacologic, biochemical and molecular investigations. Major clinical research areas of activity include congestive heart failure, hypertension and cardiomyopathies. Active clinical investigations include those concerned with pathophysiological and therapeutic aspects of heart disease, and include such disease processes as hypertension, heart failure, ischemic heart disease, and atrial fibrillation.|
|No information at this time.|
|James Moises, M.D.||Currently I am working with Nicolas Bazan at the Neuroscience Center
studying traumatic brain injury and ischemic brain injury in a rat model. We are
looking at lipid second messengers, gene expression, and potential neuroprotective agents.
Clinically, I am open to any research project a student may be interested in
conducting, with special interests in hypertension, chest pain diabetes, and sexually
transmitted diseases in the Emergency Department setting.
|Chandan Prasad, Ph.D.||Appetite regulation; Hormones and drug addiction; Neurobiology of aging;
Diet, hormone and behavior program
|Frank Svec, M.D., Ph.D.||Appetite control in fat rats. Effect of DHEA on brain chemistry.|
|Thiruven Ramakrishnan, M.D.||H. Pylori: Effect of N-Acetylchystine on bacterial survival; H. pylori:
Effect of Colony stimulating factor on infection; Pathogenesis of Barrett's Esophagus;
|Nicholas Persich, M.D.||Ascorbic acid and nitric oxide in Helicobacter pylori infection.|
|James C. Cohen, Ph.D.||Molecular genetics of aging & cancer, use of the polymerase chain
reaction to examine problems in infectious diseases
|Henry Rothschild, M.D., Ph.D.||Interaction of the environment with a gene in the cause of lung cancer; Loss of physiological function with age; Longevity genes in humans|
|Lowell B. Anthony, M.D.||Anticancer therapies using radiolabelled somatostatin analogues
|John N. Bickers, M.D.||Investigational cancer treatment; Hospice care and pain control
|Igor Espinoza-Delgado, M.D.||Cancer immunotherapy; Apoptosis and cell cycle regulation
|Paul Schwarzenberger, M.D.||Laboratory and clinical studies using gene therapy for malignant disease
|Chris Theodossiou, M.D.||Use of clomiphene for metastatic breast cancer; use of anastrozole for
Kaposis Sarcoma; use of liposomal antracyclines for prostate cancer; Clinical
oncology protocols - SWOG
|Richard H. Vial, M.D.||Clinical oncology protocols - SWOG
|Robert W. Veith, M.D.||Stimulation of fetal hemoglobin, especially in sickle cell anemia
|Donna A. Walker, M.D.||Clinical oncology protocols - SWOG; Rural oncology care and supportive
|Kenneth E. Aldridge||Clinical & medical microbiology infections
|Rebecca A. Clark, M.D.||The epidemiology and therapy of HIV infections and opportunistic
inflections in women
|Julio E. Figueroa, II, M.D.||The molecular biology of infectious causes of atherosclerosis including Chlamydia
pneumoniae. The characterization and role of a new proteo glycan identified in the
urine of patients with HIV wasting syndrome
|Michael E. Hagensee, M.D., Ph.D.||The Hagensee laboratory studies the human immune response against human
papillomavirus. Our laboratory is developing immune assyas to detect HPV-specific
antibodies from serum or mucosal sites (cervix and saliva) as well as delineating the
local immune factors from mucosal specimens. In addition, our laboratory is
developing novel PCR-based techniques to detect HPV DNA from cervical, urine, oral
specimens, Pap smears, and pathologic tissue. These techniques will be applied to
various populations at high risk for HPV infection and disease namely adolescents, gay men
with and without HIV infection and women with and without HIV infection. Results
from these studies will aid in current and future vaccine development efforts as well as
in the current diagnosis of HPV infection.
|David H. Martin, M.D.||Molecular methods for studying the epidemiology of STD's and their
diagnosis. Pathogenesis of STD's in humans.
|Stephanie N. Taylor, M.D.||The epidemiology, detection and treatment of chlamydial and gonococcal infections in adolsecents based on large scale screening programs.|
|Effrain Reisin, M.D.||The effect of obesity and weight reduction on hypertension and renal
function; the effect of new antihypertensive medication ACE inhibitors and calcium channel
blockers on hypertension and renal function.
|J. David Wallin, M.D.
M. Eileen Cook, M.D.
Carolyn J. Pearce, M.D.
|A large number of studies involving the study of the relationship between hypertension and renal diseases are being carried out in the renal section. Under the supervision of one of the investigators, an honor student will have the opportunity to recruit and follow patients in hypertension studies and learn and perform renal function studies.|
|Barbara Y. Legardeur M.P.H, L.D.||Dietary assessment; Diet and cancer; Nutrition education
|Alfredo Lopez, M.D., Ph.D.||Exercise and lipids; Nutrition and cancer; Vitamin A nutritional
status; Steroids in obesity and heart disease; Lipo-proteins and coronary heart disease;
cholesterol and gall stones.
|Joseph J. Biundo, Jr., M.D.||Rheumatoid arthritis treatment; Use of growth factors in diabetic foot
ulcers; Use of erythropoietin to prevent transfusion related complications; Geriatric
rehabilitation; Pain management; Musculoskeletal rehabilitation; The effect of Clinitron
Bed on Transcutaneous Oxygen; Shoulder diseases; Potential use of Granulocyte Macrophage
Colony Stimulating Factor (GM-CSF) in the treatment of chronic con-healing diabetic foot
|Stephen Kishner, M.D.||Shoulder problems in hemiplegia; Shoulder problems in quadriplegia;
Neuropathy in Connective Tissue Disorders; Effect of temperature on Electromyography (EMG)
Diagnosis of Carpal Tunnel Syndrome; Potential use of granulocyte macrophage colony
stimulating factor (GM-CFS) in the treatment of pressure ulcers.
|Robert C. Mipro, Jr., M.D.||Stroke rehabilitation; Musculoskeletal rehabilitation; Geriatric
rehabilitation; Diabetic foot care management; Functional independent measurement outcome
in rehabilitation; Sports medicine rehabilitation
|Mahmoud Sarmini, M.D.||Potential use of granulocyte macrophage colony stimulating factor
(GM-CSF) in the treatment of pressure ulcers; Revisiting diazepam use for spasticity in
spinal cord injury
|Furquan H. Siddiqui, M.D., ChB||Use of platelet derived growth factors in diabetic foot
and pressure ulcers; Use of Erythropoietin to prevent transfusion related complications;
The effect of Clinitron Bed on Transcutaneous Oxygen; Functional independent measurement
outcome in rehabilitation; Potential use of Granulocyte Macrophage Colony Stimulating
Factor (GM-CSF) in the treatment of chronic non-healing diabetic foot and pressure ulcers.
|Rajesh Yadav, M.D.||Use of platelet derived growth factors in diabetic foot
ulcers; Stroke rehabilitation; Spinal cord injury rehabilitation; Traumatic brain injury
rehabilitation; Use of Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) in the
treatment of chronic non-healing diabetic foot ulcers.
|Julie Brown, Ph.D.||HIV tat effects on host defense, cellular proteins that interact with tat
|Ben deBoisblanc, M.D.||ARDS & pulmonary hypertension
|Stephen Kantrow, M.D.||Mitochondrial function during sepsis and during apoptosis
|Jay K. Kolls, M.D.||Gene therapy for lung, liver, and blood disorders using viral and
|Carol Mason, M.D.||Alveolar macrophage dysfunction during sepsis; Sepsis-induced
dysfunction of respiratory defense mechanisms, bacterial translocation and lung
|Steve Nelson, M.D.||Effect of alcohol on TNF and host defense; Cytokine-induced
inflammatory lung disease; colony stimulating factors in pulmonary and systemic infection
|Judd Shellito, M.D.||Alveolar macrophage function during immunosuppression; Effect of
alcohol on pulmonary host defenses, mechanism of resistance to PCP infection
|Ann Weinacker, M.D.||Neutrophil function in HIV infection
|David A. Welsh, M.D.||Lung injury and alveolar repair mechanisms including cell-cell and
cell-extracellular matrix interations. Active lung injury models include ventilator
induced lung injury and tobacco-related lung injury.
Clinical research projects focus on HIV-associated lung disease including pneumonia diagnosis, transmission of Pneumocystis carinii and pulmonary compartmentalization of virus.
|Ping Zhang, Ph.D.||Effects of alcohol on host defense during infection and inflammation
|Luis R. Espinoza||Dr. Espinoza's research interest deals with the study of
fibroblast-derived cytokines, and growth factors in psoriatic arthritis, and search for
bacterial antigens in synovium by PCR
|Hugh McGrath, Jr.||At the moment I am treating systemic lupus erythematosus patients with
long wavelength ultraviolet light. Although the shorter wavelengths exacerbate this
disease, the longer wavelengths that in solar radiation are in balance with the shorter
wavelengths ameliorate disease. We have already established that low doses of this
light reverses clinical activity and are now in the process of determining why.
Because fatigue, lack of concentration, and mood respond briskly, we are using PET scans
to evaluate functional changes in the brain before and after therapy to account for the
improvement in mentation, fatigue, and mood. At the same time we are assessing
levels of heme oxygenase and nitric oxide, as we have reasons to believe that these are
key to the attenuation of rashes and joint pain that characterize the therapy.
Collaborating are Admasu Maru in Dr. Lancaster's lab and Jawed Alam, the Co-director of
the Dept. of Molecular Genetics. Admasu is doing the nitric oxide studies and Jawed
is managing the heme oxygenase assays. We would welcome help from any young
investigator who is interested in lupus or in the fascinating actions of ultraviolet
|Eve Scopelitis||Dr. Scopelitis is interested in osteoporosis, and in several clinical
studies using newer anti-inflammatory drugs.
|Wendell A. Wilson||Genetic origins of antiphospholipid antibodies andsystemic lupus erythematosus. The role of complement deficiencies, particularly C4, in the pathogenesis of systemic lupus erythematosus, and primary antiphospholipid antibody syndrome, is the subject of Dr. Wilson's research interest.|