2012 1:44:15 PM

Angela Martin Amedee, PhD

Professor
Microbiology, Immunology, Parasitology

1901 Perdido St., Box P6-1
New Orleans, LA 70112
Phone: (504) 568-5608
Fax: (504) 568-2918

aamede@lsuhsc.edu

Degrees

BS Microbiology - 1986
Nicholls State University, Thibodaux, LA

MS Microbiology - 1989
Louisiana State University School of Medicine

PhD Microbiology - 1992
Louisiana State University School of Medicine

Bio

Dr. Amedee received her Bachelor of Science degree from Nicholls State University in Thibodaux, LA in 1986, and her MS and PhD in Microbiology from Louisiana State University School of Medicine in New Orleans, LA in 1989 and 1992. Dr. Amedee conducted her postdoctoral training in the laboratory of Dr. Michael Murphey-Corb at Tulane National Primate Research Center and was subsequently promoted to a Research Associate in 1995. In 1997 she accepted a position as a Research Assistant Professor in the Department of Pediatric Infectious Disease at Tulane University School of Medicine. In February 2001, Dr. Amedee joined the faculty at LSUHSC in the Department of Microbiology, Immunology and Parasitology.

Research Interests

The Amedee laboratory investigates the pathogenesis of Human Immunodeficiency Virus (HIV), with a focus on the viral and host factors responsible for transmission.  The laboratory conducts animal model studies utilizing the nonhuman primate model of HIV disease, as well as clinical translational studies in HIV-infected populations and cell culture models of HIV infection.  One area of research in the laboratory involves collaborative projects with scientist from the LSUHSC Alcohol and Drug Abuse Center of Excellence to investigate the effects of alcohol consumption and drug abuse on HIV transmission and pathogenesis.  Many of these studies are done with macaques infected with Simian Immunodeficiency Virus (SIV) and are designed to identify the mechanisms responsible for sexual transmission and viral shedding in the genital mucosa.  Parallel studies in clinical populations are also ongoing.  Other studies in the laboratory investigate the mechanisms involved in mother-to-infant transmission of HIV and the establishment and maintenance of viral reservoirs in women.  This work focuses on the selection and evolution of viral genotypes in the infant, as well as viral reservoirs, viral expression, and pathogenesis in females, using both clinical and animal model studies.  The Amedee laboratory also has ongoing collaborative projects with other LSUHSC faculty that investigate the interaction of sexually-transmitted diseases with HIV.  These studies are designed to decipher the dynamics of HIV replication and genital shedding, as well as susceptibility to HIV infection in the presence of co-infections using both clinical and in vitro cell culture studies.

Teaching Activities General and Molecular Virology
Microbiology
Medical Microbiology Laboratory
Analysis of Research Literature
Medical Microbiology
Techniques in Microbiology
Selected Publications

For a list of publications, click here.

Additional Info

Jenna Rychert, PhD (graduate of LSUHSC-NO Microbiology PhD program under Angela Amedee, PhD) is now a certified Diplomate of the American Board of Medical Microbiology (ABMM).  Certification by the ABMM is recognized by federal and state governmental agencies as a significant component toward meeting licensure requirements for high complexity laboratory directors. 
American College of Microbiology Press Release