Administration Basic Sciences Clinical Sciences Centers of Excellence
 
 

Angela Martin Amedee, PhD

Associate Professor
Microbiology, Immunology, Parasitology

1901 Perdido St., Box P6-1
New Orleans, LA 70112
Phone: (504) 568-5608
Fax: (504) 568-2918

aamede@lsuhsc.edu

Degrees

BS Microbiology - 1986
Nicholls State University, Thibodaux, LA

MS Microbiology - 1989
Louisiana State University School of Medicine

PhD Microbiology - 1992
Louisiana State University School of Medicine
Bio

Dr. Amedee received her Bachelor of Science degree from Nicholls State University in Thibodaux, LA in 1986, and her MS and PhD in Microbiology from Louisiana State University School of Medicine in New Orleans, LA in 1989 and 1992. Dr. Amedee conducted her postdoctoral training in the laboratory of Dr. Michael Murphey-Corb at Tulane National Primate Research center and was subsequently promoted to a Research Associate in 1995. In 1997 she accepted a position as a Research Assistant Professor in the department of Pediatric Infectious Disease at Tulane University School of Medicine. In February 2001, Dr. Amedee joined the faculty at LSUHSC as an Assistant Professor in the Department of Microbiology, Immunology and Parasitology where she is also a member of the Center of Excellence in Oral and Craniofacial Biology.

Dr. Amedees research is on the pathogenesis and transmission of HIV and the closely related simian immunodeficiency virus (SIV). The major focus is to evaluate the parameters involved in transmission of virus from mother-to-infant.

Other areas of interest include the identification and quantitation of viral genotypes expressed at mucosal surfaces and characterization of HIV/SIV envelope sequences that emerge during disease progression.
Research Interests Pathogenesis and mother-to-infant transmission of human and simian immunodeficiency viruses (HIV and SIV)
Teaching Activities General and Molecular Virology
Microbiology
Medical Microbiology Laboratory
Analysis of Research Literature
Medical Microbiology
Techniques in Microbiology
Selected Publications

Amedee, A.M., Lacour, N., and Ratterree, M., Mother-to-infant transmission of SIV via breastfeeding in rhesus macaques., J. Med. Primatology 32:187-193, 2003.

Bell, I., Schaefer, T.M., Amedee, A.M., and Reinhart, T.A., Down-modulation of the co-stimulatory molecule, CD28, is a conserved activity of multiple SIV nefs and is dependent on histidine 196 of nef., Virology 283:148-158, 2000.

Robinson, J.E., Cole, K.S., Elliott, D.H., Lam, H., Amedee, A.M., Means, R., Desrosiers, R.C., Clements, J., Montelaro, R.C., Murphey-Corb, M., Production and characterization of SIV envelope-specific rhesus monoclonal antibodies from a macaque asymptomatically infected with a live SIV vaccine., AIDS Res Hum Retroviruses 14:1253-1262, 1998.

Edinger, A.L., Amedee, A.M., Miller, K., Doranz, B.J., Endres, M., Sharron, M., Samson, M., Clements, J.E., Murphey-Corb, M., Peiper, S.C., Parmentier, M., Broder, C.C., and Domes, R.W., Differential Utilization of CCR5 by Macrophage and T-cell Tropic SIV Strains., Proc. Natl. Acad. Sci. USA 94:4005-4010, 1997.

Amedee, A.M., Lacour, N., Gierman, J.L., Martin, L.N., Clements, J.E., Bohm, Jr., R.B., Harrison, R., and Murphey-Corb, M., Genotypic Selection of Simian Immunodeficiency Virus (SIV) in Macaque Infants Infected Transplacentally., J Virol 69:7982-7990, 1995.
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