
| Administration | Basic Sciences | Clinical Sciences | Centers of Excellence |
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| Degrees |
PhD - 1986 MD - 1988 |
| Bio |
Medical School: Baylor College of Medicine; Residency: University of Washington; Fellowship: University of Washington The Hagansee laboratory studies the human immune response against human papillomavirus. Our laboratory is developing immune assays to detect HPV-specific antibodies from serum or mucosal sites (cervix and saliva) as well as delineating the local immune factors from mucosal specimens. In addition, our laboratory is developing novel PCR-based techniques to detect HPV DNA from cervical, urine, oral specimens, Pap smears, and pathologic tissue. These techniques will be applied to various populations at high risk for HPV infection and disease namely adolescents, gay men with and without HIV infection and women with and without HIV infection. Results from these studies will aid in current and future vaccine development efforts as well as in the current diagnosis of HPV infection. |
| Research Interests |
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| Selected Publications |
Lilly EA, Cameron JE, Shetty KV, Leigh JE, S. Hager, McNulty KM, Cheeks C, Hagensee M and Fidel Jr. PL, Lack of evidence for local immune reactivity in oral hairy leukoplakia and oral wart lesions., Oral Micro. Immunol. 20:154-162, 2005. Bolt J, Vo QN, Kim WJ, McWhorter AJ, Thomson J, Hagensee ME, Friedlander P, Brown KD, Gilbert J, The ATM/p53 pathway is commonly targeted for inactivation in squamous cell carcinoma of the head and neck (SCCHN) by multiple molecular mechanisms, Oral Oncol. 41(10):1013-20, 2005 Nov. Chaturvedi AK, Myers L, Hammons AF, Clark RA, Dunlap K, Kissinger P, Hagensee ME: Prevalence and clustering patterns of human papillomavirus genotypes in multiple infections. Cancer Epidemiol Biomarkers Prev 2005;14:2439-2445. Lillis RA, Dugan V, Mills T, Berner A, Sanders CV, Hagensee M, Lopez FA. A fish hook and liver disease: revisiting an old enemy. J La State Med Soc 154:20-25, Jan/Feb 2002. Slavinsky, J., 3rd, P. Kissinger, L.Burger, A. Boley, RP DiCarlo, ME Hagensee, Seroepidemiology of low and high oncogenic risk types of human papillomavirus in a predominantly male cohort of STD clinic patients, Int J STD AIDS 12(8): 516-23, 2001. Hagensee, M. E., Infection with Human Papillomavirus: Update on Epidemiology, Diagnosis, and Treatment, Curr Infect Dis Rep 2(1): 18-24, 2000. Hagensee, M. E., L. A. Koutsky, et al, Detection of cervical antibodies to human papillomavirus type 16 (HPV-16) capsid antigens in relation to detection of HPV-16 DNA and cervical lesions, J Infect Dis 181(4): 1234-9, 2000. Hagensee, M. E., J. Slavinsky, 3rd, et al, Seroprevalence of human papillomavirus type 16 in pregnant women, Obstet Gynecol 94(5 Pt 1): 653-8, 1999. Madeleine, M. M., J. R. Daling, et al, Cofactors with human papillomavirus in a population-based study of vulvar cancer, J Natl Cancer Inst 89(20): 1516-23, 1997. |
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