Administration Basic Sciences Clinical Sciences Centers of Excellence
Department Title
Spotlight Section New Orleans
 

  

Ludmila Belayev, MD

Research Associate Professor of Neurosurgery and Neuroscience

2020 Gravier Str
Suite 9B4, Room 946A
New Orleans, LA 70112

Phone: (504) 599-0849

Fax: (504) 599-0488

lbelay@lsuhsc.edu

Degrees

MD - 1976
Medical University School, Novosibirsk, Russia

Bio

2006 to present: Research Associate Professor of Neurosurgery and Neuroscience, LSUHSC, Neuroscience Center

2005 to 2006: Director of Commercial Research and Pharmacology, Inotek Pharmaceuticals Corporation

2003 - 2005: Research Associate Professor, Department of Neurology, University of Miami School of Medicine

1998 - 2003: Research Assistant Professor, Department of Neurology, University of Miami School of Medicine

1994 – 1998: Postdoctoral Research Associate, Department of Neurology, University of Miami School of Medicine

1992-1994: Neuroscientist, Department of Pharmacology, Pharmos Corp., Rehovot, Israel

1979-1990: Neurosurgeon, Department of Neurosurgery, Novosibirsk Regional Hospital, Russia,

1989: Neurovascular Fellowship-Institute of Neurosurgery N.N. Burdenko, Moscow, Russia

1991: Course of Internal Medicine, Ishilov Hospital, Tel-Aviv, Israel


CURRENT RESEARCH PROJECTS
Neuroprotection study with LAU-0901 in focal cerebral ischemia.

DHA and DHA-Albumin studies in the experimental stroke models.

Development and evaluations of Fluid Percussion Injury model in rats.
 

Research Interests Development and evaluation of animal models of stroke
Development and evaluation of animal models of traumatic brain injury
Recovering function after brain injury (neural plasticity and reorganization), expertise in different neurobehavioral tests
Evaluation of blood-brain integrity
Histopathology and image analysis of the brain after stroke and head trauma
Neuroprotection in brain ischemia and traumatic brain injury
Non-clinical animal pharmacology, pharmacokinetics and toxicology studies
Selected Publications

L. Belayev. Mouse Intracerebral Hemorrhage Model.  In: Jun Chen, Zao Xu, Xiao-Ming Xu, and John Zhang, (Eds),  Animal Models of Acute Neurological Injuries, The Humana Press Inc, 349-357, 2009.

Belayev L, Khoutorova L, Atkins K, Cherqui A, Alvarez-Builla J, Bazan NG.  LAU-0901, a novel platelet-activating factor receptor antagonist, confers enduring neuroprotection in experimental focal cerebral ischemia in the rat. Brain Res, 1253, 184-190, 2009.

Belayev L, Khoutorova L, Atkins K, Gordon WC, Bazan NG.  LAU-0901, a novel platelet-activating factor antagonist, is highly neuroprotective in cerebral ischemia. Exp. Neurol, 214, 253-258, 2008.

Belayev L, Obenaus A, Zhao W, Saul I, Busto R, Wu C, Vigdorchik A, Lin B, Ginsberg MD: Experimental intracerebral hematoma in the rat: characterization by sequential magnetic resonance imaging, behavior, and histopathology. Effect of albumin therapy, Brain Res 1157, 146-155, 2007.

Belayev L, VL Marcheselli, L. Khoutorova, EB. Rodriguez de Turco, R. Busto, MD Ginsberg, NG Bazan: Docosahexaenoic acid complexed to albumin elicits high-grade ischemic neuroprotection, Stroke 36, 118-123, 2005.

Belayev L, Khoutorova L, Zhao W, Vigdorchik A, Belayev A, Busto R, Magal E, Ginsberg MD: Neuroprotective effect of darbepoetin alfa, a novel recombinant erythropoietic protein, in focal cerebral ischemia in rats, Stroke 36, 1071-6, 2005.

Belayev L, Saul I, Busto R, Danielyan K, Vigdorchik A, Khoutorova L, Ginsberg MD: Albumin treatment reduces neurological deficit and protects blood-brain barrier integrity after acute intracortical hematoma in the rat, Stroke 36, 326-31, 2005.

Zhang Y, Belayev L, Zhao W, Irving EA, Busto R, Ginsberg MD: A selective endothelin ET(A) receptor antagonist, SB 234551, improves cerebral perfusion following permanent focal cerebral ischemia in rats, Brain Res 1045, 150-156, 2005.

Ley JJ, Vigdorchik A, Belayev L, Zhao W, Busto R, Khoutorova L, Becker DA, Ginsberg MD: Stilbazulenyl nitrone, a second-generation azulenyl nitrone antioxidant, confers enduring neuroprotection in experimental focal cerebral ischemia in the rat: neurobehavior, histopathology, and pharmacokinetics, J Pharmacol Exp Ther 313, 1090-100, 2005.

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