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Administration Basic Sciences Clinical Sciences Centers of Excellence
 

 

  

Ludmila Belayev, M.D.

Professor/Research Neurosurgery, Neurology and Neuroscience

2020 Gravier Street
Suite 9B4, Room 946A
New Orleans, LA 70112

Phone: (504) 599-0849

Fax: (504) 599-0488

lbelay@lsuhsc.edu

Degrees

Medical University School, Novosibirsk, Russia, Neurosurgery, 1978-1982.

Medical University School, Novosibirsk, Russia, Surgery, 1977-1978.

Medical University School, Novosibirsk, Russia, M.D., 1970-1976.

Post-Doctoral Fellowships: Cerebral Vascular Disease Research Center, Department of Neurology, University of Miami School of Medicine, 1994-1996.

Bio

2013 to present: Professor of Neurology, School of Medicine, LSUHSC

2012 to present: Professor of Neurosurgery and Neuroscience, School of Medicine, LSUHSC

2006 to 2012: Research Associate Professor of Neurosurgery and Neuroscience, School of Medicine, LSUHSC

2005 to 2006: Director of Commercial Research and Pharmacology, Inotek Pharmaceuticals Corporation

2003-2005: Research Associate Professor, Department of Neurology, University of Miami School of Medicine

1998-2003: Research Assistant Professor, Department of Neurology, University of Miami School of Medicine

1994-1998: Postdoctoral Research Associate, Department of Neurology, University of Miami School of Medicine

1992-1994: Neuroscientist, Department of Pharmacology, Pharmos Corp., Rehovot, Israel

1979-1990: Neurosurgeon, Department of Neurosurgery, Novosibirsk Regional Hospital, Russia

1989: Neurovascular Fellowship-Institute of Neurosurgery N.N. Burdenko, Moscow, Russia

1991: Course of Internal Medicine, Ishilov Hospital, Tel-Aviv, Israel


CURRENT RESEARCH PROJECTS
Neuroprotection study with LAU-0901 in focal cerebral ischemia.

DHA and DHA-Albumin studies in the experimental stroke models.

Development and evaluations of Fluid Percussion Injury model in rats.
 

Research Interests

I.  Development and evaluation of animal models of stroke:

Models of global cerebral ischemia in rats and mice:

a)    Two-vessel occlusion model of forebrain ischemia
b)    Four-vessel occlusion model of forebrain ischemia

Models of focal cerebral ischemia in rats and mice:
a)    Middle cerebral artery occlusion by intraluminal suture
b)    Mechanical (electrocoagulation, microclip)

Hemorrhagic models in rats and mice:
a)    Intracerebral hemorrhagic models (blood, collagenase)
b)    SAH and vasospasm: (injection of blood into cisterna magna and puncture of cerebral artery)

II. Development and evaluation of animal models of traumatic brain injury:
a)    Lateral fluid percussion injury model
b)    Controlled weight drop brain injury

III. Recovering function after brain injury (neural plasticity and reorganization), expertise in different neurobehavioral tests.

IV. Evaluation of blood-brain integrity.

V. Histopathology and image analysis of the brain after stroke and head trauma.

VI. Neuroprotection in brain ischemia and traumatic brain injury. 

VII. Non-clinical animal pharmacology, pharmacokinetics and toxicology studies.

Committees & Administrative Responsibilities

Committees & Administrative Responsibilities
Peer Review Study committees:

Reviewer, NIH, BINP study section, Washington, DC, 2011 - to current

Reviewer, NIH, Brain Disorders and Clinical Neurosciences, ZRG1 BDCN-Y-02 Special Emphasis Panel, - 2010.

Reviewer, Department of Veterans Affairs, Regenerative Medicine and Spinal Cord Injury panel, Washington, DC, - 2010.

Member, American Heart Association, Brain– Basic-Peer Review Study Group, 2010- to current

Member, American Heart Association, Region 4 Brain 2-Peer Review Study Group, 2009

 

Editorial Board:

Experimental & Translational Stroke Medicine (2012 – to current)

ISRN Neurology (2010- to current)

The Science Advisory Board (2010- to current)

BMC Neurology (2003–to current)

Stroke (2005-2007)

Selected Publications

Selected Publications

Book Chapters:

  • L. Belayev. Overcoming barriers to translation from experimental stroke models. In: Lapchak and Zhang (Eds),
    Stroke targets to clinical trials, Springer, Chapter 24, 471-492, 2012.
     
  • L. Belayev, Y. Lu, NG Bazan. Brain ischemia and reperfusion: cellular and molecular mechanisms in stroke injury.
    In: Brady, Albers, Price, Siegel (Eds),  Basic Neurochemistry, Elsevier, Chapter 35, 621-642, 2012.
     
  • L. Belayev, M. Endres and V. Prinz. Focal cerebral ischemia in the mouse and rat using the intraluminal suture-filament model.
    In: U. Dirnagl, (Ed),  Rodent Models of Stroke, The Springer, Chapter 4, 29-40, 2010.
     
  • L. Belayev. Mouse Intracerebral Hemorrhage Model.  In: Jun Chen, Zao Xu, Xiao-Ming Xu, and John Zhang, (Eds),
    Animal Models of Acute Neurological Injuries, The Humana Press Inc, 349-357, 2009.

Journal Publications: