PATHIST HRLM-TEM TEACHING CASES		PATHIST MOAR-MET CASOS DE ENSEÑANZA
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HRLM-TEM home page.	Teach Cases Index	MOAR-MET pagina frontal.	Indice Casos Ensenanza
CASE # 4		CASO # 4
WHAT IS YOUR DIAGNOSIS? Identify the numbered structures and try to make adiagnosis.  See the answers  by clicking on LESIONS & DIAGNOSIS.		CUAL ES SU DIAGNOSTICO? Identifique las estrcuturas numeradas y trate de hacer un diagnostico. Vea las respuestas  pulsando sobre LESIONES & DIAGNOSTICO.
CLINICAL INFORMATION: A 60 year old female complained of a nodule in the vagina for several months. LM studies suggested lymphoma but the mass was resistant to treatment. No other tumors were found. The sample in the paraffin block was deparaffinized and submitted for TEM studies.		INFORMACION CLINICA: Una mujer de 60 años se presenta con una masa en la vagina. ML suggiere un lymphoma pero la masa no cede al tratamiento. La muestra del bloque de paraffina se deparafinizo y uso para MET.
Fig 1: H&E		Fig 2: H&E
Fig 3: HRLM		Fig 4: HRLM
Fig 5:TEM		Fig 6: TEM
Other tests: Ipx: Positive S 100 protein.		Otras pruebas: IPx positivo: S 100 protein,
LESIONS & DIAGNOSIS 1. Vagina lining epithelium. 2, 3. Tumor cells. 4. Tumor cells with pigment granules. 5. Red cells. 6. Abnormal premelanosomes and melanosomes. DIAGNOSIS: VAGINA, MALIGNANT MELANOMA.		LESIONES Y DIAGNOSTICO 1. Epitelio vaginal. 2, 3. Células tumorales. 4. Células tumorales con pigmento. 5. Eritrocitos. 6. Premelanosomas y melanosomas anormales.
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