MORPHOLOGIC DIAGNOSIS OF CRESCENTIC GLOMERULOPATHIES. ILLUSTRATIONS
Dr. Ernesto O. Hoffmann. Professor of Pathology. Louisiana State University Medical Center and VA Medical Center. New Orleans, Louisiana, USA. Noviembre 2003.	CIN 2003
Local Navegational Box:  Crescents Home

1. The sample has Crescents and Recognizable Underlying Glomerulopathy:
1.1. CR with Underlying immune complex GN:
Epithelial Crescent. Membranous GN.	Epithelial Crescent. Post-Infectious GN.
1.2.Crescents with underlying metabolic diseases:
No pictures in our files. (See ref. 11).
1.3. Crescents with Glomerular dysmorphism:
	(No phtographs in our files. See ref 5)
Epithelial Crescents. Focal Segmental Glomerulosclerosis.	Crescents. Alport's Syndrome.
1.4. Crescents with other Complications (Glomerulitis):
Fibroepithelial crescents. Thrombotic Microangiopathy.	Epithelial Crescents. Acute allograft rejection.
2. The sample has CRs but no recognizable underlying GP. HRLM and TEM negative for immune deposits. FM shows linear pattern with C3 and IgG along the GBM (occasionally also anti TBM):
Epithelial Crescents with necrosis and fibrin. Anti GBM Glomerulitis (Goodpasture Syndrome).
3. The renal biopsy shows glomerular CRs but no recognizable GP. FM, HRLM and TEM are negative for immune deposits. No linear pattern by FM:
3.1. Biopsy positive for vasculitis:
Epithelial Crescent with necrosis and fibrin. Micro Polyarteritis Nodosa.	Crescent on Wegeners Granulomatosis.
3.2. Biopsy negative for vasculitis:
History of sepsis, leukemia, renal infarct, medication.	No photographs in our files (See ref. 5).
4. No underlying GPs by HRLM, TEM. ANCA and FM are negative, no vascultis, no endocarditis, no abcesses, no others, no clinical history.
Idiopathic Crescentic Glomerulitis.	Idiopathic Crescentic Glomerulitis.