Charles D. Nichols, PhD

Nichols C.D. (2009). Serotonin 5-HT2A receptor function as an underlying factor contributing to both cardiovascular and psychiatric disease. Cardiovascular Psychiatry and Neurology. In press.

Nichols C.D. and B.L. Roth (2009). Engineered G-protein coupled receptors as a tool to investigate biological processes. Frontiers in Molecular Neuroscience. In press.

Johnson, O. J. Becnel, and C.D. Nichols (2009). Serotonin 5-HT1A and 5-HT2 receptors modulate different aspects of aggressive behaviors in Drosophila. Neuroscience. 4:1292-1300.

Duvernay M.T., Dong C., Zhang X., Zhou F., Nichols C.D., G. Wu (2009). Anterograde trafficking of G protein-coupled receptors: function of the C-terminal F(X)6LL motif in export from the endoplasmic reticulum. Molecular Pharmacology. 75:751-61.

Yu, B.,  J. Becnel, M. Zerfaoui, R. Rohatgi, H. Boulares, C. D. Nichols. (2008). Serotonin 5-HT2A receptor activation suppresses TNF--induced inflammation with extraordinary potency. Journal of Pharmacology and Experimental Therapeutics. 327(2):316-23. *Featured article with commentary*

Nichols, D.E. and C.D. Nichols (2008). Serotonin Receptors. Chemical Reviews. 108(5):1614-1641.

Zerfaoui, M., Y. Suzuki, A.S. Naura, C.P.Hans, C.D. Nichols, A.H. Boulares (2008). Nuclear translocation of p65 NF-kB is sufficient for VCAM-1, but not ICAM-1, expression in TNF-stimulated smooth muscle cells: Differential requirement for PARP-1 expression and interaction. Cellular Signalling, 20:186-194.

Nichols, C.D. (2007). 5HT2 receptors in Drosophila are expressed in the brain and modulate aspects of circadian behaviors. Dev. Neurobiol. 67:752-763.

Nichols, C.D. (2006). Drosophila melanogaster neurobiology, neuropharmacology, and how the fly can inform CNS drug discovery. 2006. Pharmacol Ther. 112(3):677-700.

Marvanova, M, and C.D. Nichols. (2007). Identification of neuroprotective compounds of C. elegans dopaminergic neurons against 6-OHDA. J Mol Neurobiol. 31:131-141.

Behan, K.J., Fair, J., Sing, S., Bogwitz, M., Perry, T., Grubor, V., Cunningham, F., Nichols, C.D., Cheung, T., Batterham, P., and J.A. Pollock. (2005). Alternative splicing removes an Ets interaction domain from Lozenge during Drosophila eye development. Dev Genes Evol, Aug;215(8):423-35.

Nichols, C.D., and E. Sanders-Bush (2004). Molecular genetic responses to lysergic acid diethylamide include transcriptional activation of MAP Kinase Phosphatase-1, C/EBP-, and ILAD-1, a novel gene with homology to arrestins. J Neurochem, Aug;90(3):576-84.

Nichols, C.D., E.E. Garcia, and E. Sanders-Bush (2003). Dynamic changes in prefrontal cortex gene expression following lysergic acid diethylamide administration. Mol Brain Res, 111: 182-188.

Nichols, C.D., J. Ronesi, W. Pratt, and E. Sanders-Bush (2002). Hallucinogens and Drosophila: Linking serotonin receptor activation to behavior. Neuroscience, 115: 979-984.

Nichols, C.D. and E. Sanders-Bush 2002). A single dose of lysergic acid diethylamide influences gene expression patterns within the mammalian brain. Neuropsychopharmacology, 26(5): 634-42.

Behan, K. J., C.D. Nichols, T. Cheung,  J. Fair, B. Hogan, P. Batterham,  and J. A. Pollock (2002). Yan regulates Lozenge through an eye specific enhancer in Drosophila. Dev Genes Evol, 212:267–276.

É. L. S Loreto, A. Zaha, C. Nichols, J. A. Pollock, and V. L. S. Valente (1998). Characterization of a hypermutable strain of Drosophila simulans. CMLS, Cell. Mol. Life Sci. 54: pp 1283-1290.

Pollock, J.A., A. Assaf, A. Peretz, C.D. Nichols, M.H. Mojet, R.C. Hardie, and B. Minke (1995).  TRP, a Protein Essential for Inositide-Mediated Ca2+ Influx Is Localized Adjacent to the Calcium Stores in Drosophila Photoreceptors. J. Neuroscience, 15(5):3747-3760.