Kim Pedersen, PhD

 2010%209:21:09%20AM

Position

Postdoctoral researcher

Lab

MEB 5219

Phone

504 568 2794

Education

Cand. Scient. From University of Copenhagen

Degree

PhD from LSUHSC, New Orleans

Research Interests 

Diabetes, Metabolic Syndrome, Angiotensin signaling

Associations

American Diabetes Association

Publications  

 

Pedersen, K. B., Chhabra K. H., Nguyen, V. K., Xia H., Lazartigues E. 2013.” The transcription factor HNF1α induces expression of angiotensin-converting enzyme 2 (ACE2) in pancreatic islets from evolutionarily conserved promoter motifs.” Biochim. Biophys. Acta. 1829:1225-35.

Pedersen, K. B. and Lazartigues, E. 2013. “Determination of Sex Differences in Activities of Angiotensin-Converting Enzyme 2 (ACE2) Requires an Activity Assay That Doesn't Underestimate ACE2.” Am. J. Hypertens. 26:1172.

Chhabra, K. H., Xia, H., Pedersen, K. B., Speth, R. C., Lazartigues, E. 2013. “Pancreatic Angiotensin-Converting Enzyme 2 (ACE2) improves glycemia in angiotensin II-infused mice”. Am. J. Physiol. Endocrinol. Metab. 304: E874-E884.

Pedersen, K. B., Sriramula S., Chhabra K. H., Xia H., Lazartigues E. 2011. “Species-specific inhibitor sensitivity of angiotensin-converting enzyme 2 (ACE2) and its implication for ACE2 activity assays” Am. J. Physiol. Regul. Integr. Comp. Physiol. 301: R1293-R1299.

Chhabra K., Pedersen K. B., Lazartigues. “Renin-angiotensin system and diabetes”. In: “Beta Cells: Functions, Pathology and Research” p. 151 - 163, 2011, Ed. Gallagher SE. NOVA Publishers

Pedersen, K. B., Buckley, R. S., Scioneaux, R. 2010. “Glucose induces expression of rat pyruvate carboxylase through a carbohydrate response element in the distal gene promoter” Biochem. J. 426: 159-170.

 Collier, J. J.; Zhang P.; Pedersen, K. B.; Haycock, J. W.; Scott, D. K. 2007. “c-Myc and ChREBP regulate glucose-mediated expression of the L-type pyruvate kinase gene in INS-1-derived 832/13 Cells”. Am. J. Physiol. Endocrinol. Metab. 293: E48-E56.

Pedersen, K. B.; Zhang, P.; Doumen, C.; Charbonnet, M., Lu, D.; Newgard, C.; Haycock, J. W.; Lange, A.J.; Scott, D. K. 2007. “The Promoter for the Gene Encoding the Catalytic Subunit of Rat Glucose-6-phosphatase Contains Two Distinct Glucose-responsive Regions” Am. J. Physiol. Endocrinol. Metab. 292: E788-E801.

Geng, C.-d.; Pedersen, K. B.; Nunez, B. S.; and Vedeckis, W. V. 2005. “Human Glucocorticoid Receptor alpha Transcript Splice Variants with Exon 2 Deletions: Evidence for Tissue- and Cell Type-Specific Functions”. Biochemistry 44: 7395-7405.

Nunez, B. S.; Geng, C.-d.; Pedersen, K. B.; Millro-Macklin, C. D.; and Vedeckis, W. V. 2005. “Interaction between the Interferon Signaling Pathway and the Human Glucocorticoid Receptor Gene 1A Promoter”. Endocrinology 146: 1449-1457.

Pedersen, K. B.; Geng, C.-d.; and Vedeckis, W. V. 2004. “Three Mechanisms Are Involved in Glucocorticoid Receptor Autoregulation in a Human T-Lymphoblast Cell Line”. Biochemistry 43: 10851-10858.

Pedersen, K. B. and Vedeckis, W. V. 2003. “Quantification and Glucocorticoid Regulation of Glucocorticoid Receptor Transcripts in Two Human Leukemic Cell Lines”. Biochemistry 42: 10978-10990.