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J. Robert Reed, PhD

Associate Professor of Research

LSU Health Sciences Center

  1901 Perdido Street P7-1
New Orleans, LA 70112 Phone: (504) 568-4740
Fax: (504) 568-2361

rreed@lsuhsc.edu

Website

Degrees

PhD - 1995
University of Nevada, Reno, NV

Selected Publications

Reed, J.R.; Eyer, M.; and Backes, W.L. (2010) Functional interactions between cytochromes P450 1A2 and 2B4 require both enzymes to reside in the same phospholipid vesicle: evidence for physical complex formation. Jour. Biol. Chem. 285: 8942-8952. (PMCID: PMC2838316)

Reed, J.R.; Huber III, W.J.; and Backes, W.L. (2010) Human heme oxygenase-1 efficiently catabolizes heme in the absence of biliverdin reductase. Drug Metab. Dispos. 38: 2060-2066. (PMCID:PMC2967390)

Reed, J.R.; Cawley, G.F.; and Backes, W.L. (2011) Inhibition of cytochrome P450 1A2-mediated metabolism and production of reactive oxygen species by heme oxygenase-1 in rat liver microsomes. Drug Metab. Lett.5: 6-16. (PMCID:PMC3252637)

Reed, J.R.; and Backes, W.L. (2012) Formation of P450 • P450 complexes and their effect on P450 function. Pharmacol. Ther. 133: 299-310. (PMCID:PMC3272114)

Reed, J.R.; Connick, J.P.; Cheng, D.; Cawley, G.F.; and Backes, W.L. (2012) Effect of homomeric P450-P450 complexes on P450 function. Biochem. J. 446: 489-497. (PMCID:PMC3518449)

Reed, J.R.; Cawley, G.F.; and Backes, W.L. (2013) Interactions between cytochromes P450 2B4 (CYP2B4) and 1A2 (CYP1A2) lead to alterations in toluene disposition and P450 uncoupling. Biochemistry  52:4003-4013. (PMID:23475771)