MD - 1978
Dr. Nelson is Dean of LSUHSC School of Medicine, John H. Seabury Professor of Medicine, Professor of Physiology and the Director and Principal Investigator of the Alcohol Research Center. The Alcohol Research Center, a large interdepartmental project funded by the National Institute on Alcohol Abuse and Alcoholism with an annual budget of 2 million dollars per year. His major clinical interests include pneumonia, adult cystic fibrosis and sepsis. His research interests are primarily directed at 1) understanding normal pulmonary host defense mechanisms, 2) defining how disease states undermine and disrupt these defense mechanisms, and 3) determining the potential of biological response modifiers to provide innovative approaches to both the prevention and treatment of pulmonary infections. Dr. Nelson is on the editorial board of several prominent journals, and is a member of the Best Doctors in America.
Research: host defense; sepsis; cytokines
Happel KI, Odden AR, Zhang P, Shellito JE, Bagby GJ and Nelson S, Acute alcohol intoxication suppresses the interleukin-23 response to Klebsiella pneumoniae infection, Alcohol Clin Exp Res 30:1200-1207, 2006.
Bagby GJ, Zhang P, Purcell J, Didier PJ and Nelson S, Chronic binge ethanol consumption accelerates progression of SIV disease, Alcohol Clin Exp Res 30:1781-1790, 2006.
Mason CM and Nelson S, Pulmonary host defenses and factors predisposing to lung infection, Clin Chest Med 26: 11-17, 2005.
Zhang P, Quinton LJ, Gamble L, Bagby GJ, Summer WR, and Nelson S, The granulopoietic cytokine response and enhancement of granulopoiesis in mice during endotoxemia, Shock 23:344-352, 2005.
Mason CM, Dobard E, Zhang P, Nelson S, Alcohol exacerbates murine pulmonary tuberculosis, Infect Immun 72:2556-2563, 2004.
Molina PE, Hoek JB, Nelson S, Guido DM, Lang CH, Wands JR, and Crawford JM, Mechanisms of alcohol-induced tissue injury, Alcohol Clin Exp Res 27:563-575, 2003.