Certification
General Neurology
Leadership
American Academy of Neurology
American Association of Neuromuscular and Electrodianostic Medicine
National Ataxia Foundation
Epilepsy Foundation of Louisiana Physician Advisory Board Member
American Red Cross Disaster Action Team Member
Publications
1. Vera-Ramirez, M., Charlet, M., Parry, G.J. - Recurrent Aspect Meningitis Complicating Intravenous lmmunoglobulin
Therapy for chronic Inflammatory Demyelinating Polyradiculoneuropathy. Neurology August
1992; 42: 1636-1637.
2. Switching from Immediate-Release to Extended-Release Carbamazepine Capsules: Safety
and Tolerability in Adolescents with Epilepsy. Michael Charlet MD, Leonard J. Chabert Medical Center, Houma, LA, USA Presented at the American Epilepsy
Society; December 3-7, 2004; New Orleans, LA.
3. Switching to Carbamazeipine Extended Release Capsules from Immediate Release Formulations:
Evaluation of Safety and Tolerability in Patients with Epilepsy. Michael Charlet MD, Leonard J. Chabert Medical Center, Houma, LA, USA Presented at the American Academy
of Neurology; April 9-16, 2004; Miami, FL.
4. Transitioning from Immediate-Release to Extended-Release Carbamazepine: Safety
and Tolerability in Patients with Epilepsy. Michael Charlet MD, Leonard J. Chabert Medical Center, Houma, LA, USA Presented at the Joint Annual
Meeting of the American Epilepsy Society and the American Clinical Neurophysiology
Society; December 2-6, 2005; Washington DC.
Research
Co-investigator of "A Double-Blind, Parallel, Placebo Controlled, Multiple Dose, 6-month
Study Assessing the Safety and Efficacy of Daily Subcutaneous Injections of Recombinant
Human Ciliary Neurotrophic Factor (rhCNTF) in Patients with Amyotrophic Lateral Sclerosis
(ALS)
SPEQT (Safety, Preference, Effectiveness, Quality of Life, and Tolerability)
A multicenter, open-labeled, phase 4 study to assess the tolerability, safety, and
effectiveness of changing treatment from carbamazepine immediate-release to carbatrol
extended-release capsules in epilepsy subjects within a community-based population.
Michael Charlet-PI
Co-investigator of WARCEF (Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction).
A randomized, double blind, multi-center clinical trial to determine whether warfarin
or aspirin is superior for preventing mortality and stroke combined in patients with
ejection fraction less than 30%, when balanced against any risk of intracerebral hemorrhage.
Principal Investigator in Eisai Clinical Study Protocol: E2007-G000-304. Study Title:
A Double-Blind, Placebo-Controlled, Dose-Escalation, Parallel-Group Study to Evaluate
the Efficacy and Safety of E2007 (perampanel) Given as Adjunctive Therapy in Subjects
with Refractory Partial Seizures
POLES- An open-label extension phase of the double-blind, placebo-controlled, doseescalation,
parallel-group study to evaluate the efficacy and safety of E2007
(Perampanel) given as adjunctive therapy in subjects with refractory partial seizures;
Sponsor: Eisai Medical Research; Pl-Dr. Michael Charlet; SI-Christine Thistlethwaite
VERSA (VIMPAT EFFICACY RESPONSE AND SAFETY AS FIRST ADD-ON) AN OPEN-LABEL, MULTICENER,
MULTINATIONAL STUDY OF LACOSAMIDE AS FIRST ADD-ON ANTIEPILEPTIC DRUG (AED) TREATMENT
IN SUBJECTS WITH PARTIALONSET SEIZURES
Pl-Dr. Michael Charlet; I - Christine Thistlethwaite; Sponsor - Schwarz Biosciences,
lnc./UCB; CRO-Parexel Clinical Research
LADS (LYRICA ANTI-EPILEPTIC DRUG STUDY) A DOUBLE-BLIND, RANDOMIZED, MUL TICENTER EFFICACY
AND SAFETY STUDY OF PREGABLIN (L YRICA) AS MONOTHERAPY IN PATIENTS WITH PARTIAL SEIZURES
Pl- Dr. Michael Charlet, SI - Christine Thistlethwaite; Sponsor-Pfizer
LOPES (L YRICA OPEN-LABEL EXTENSION STUDY) AN OPEN-LABEL
MUL TICENTER EXTENSION STUDY TO DETERMINE LONG TERM SAFETY AND EFFICACY OF PREGABABLIN
(LYRICA) AS MONOTHERAPY IN PATIENTS WITH PARTIAL SEIZURES
Pl-Dr. Michael Charlet; SI-Christine Thistlethwaite; Sponsor-Pfizer
CARBS Open-Label Study to Assess the Safety and Tolerability of Intravenous Carbamazepine
as Short-Term Replacement of Oral Carbamazepine in Adult Patients with Epilepsy; Pl-
Dr. Michael Charlet, SI - Christine Thistlethwaite Sponsor: Lundbeck Inc. Pfizer
study A0081194(PRADA): "A Randomized, Double-Blind, Placebo-Controlled, Parallel Group,
Multi-Center Trial of Pregabalin Controlled Release Formulation as Adjunctive Therapy
in Adults with Partial Onset Seizures" Pl- Dr. Michael Charlet