Publications

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Becnel D, Abdelghani R, Nanbo A, Avilala J, Kahn J, Li L, Lin Z. Pathogenic Role of Epstein-Barr Virus in Lung Cancers. Viruses. 2021 May 11;13(5). doi: 10.3390/v13050877. Review. PubMed PMID: 34064727; PubMed Central PMCID: PMC8151745. 

 

Avilala J, Becnel D, Abdelghani R, Nanbo A, Kahn J, Li L, Lin Z. Role of Virally Encoded Circular RNAs in the Pathogenicity of Human Oncogenic Viruses. Front Microbiol. 2021;12:657036. doi: 10.3389/fmicb.2021.657036. eCollection 2021. Review. PubMed PMID: 33959113; PubMed Central PMCID: PMC8093803.

 

Lin HY, Fu Q, Kao YH, Tseng TS, Reiss K, Cameron JE, Ronis MJ, Su J, Nair N, Chang HM, Hagensee ME. Antioxidants Associated with Oncogenic HPV Infection in women. J Infect Dis. 2021 Mar 18;. doi: 10.1093/infdis/jiab148. [Epub ahead of print] PubMed PMID: 33735375. 

 

Del Valle L, Dai L, Lin HY, Lin Z, Chen J, Post SR, Qin Z. Role of EIF4G1 network in non-small cell lung cancers (NSCLC) cell survival and disease progression. J Cell Mol Med. 2021 Mar;25(6):2795-2805. doi: 10.1111/jcmm.16307. Epub 2021 Feb 4. PubMed PMID: 33539648; PubMed Central PMCID: PMC7957206. 

 

Chen J, Goyal N, Dai L, Lin Z, Del Valle L, Zabaleta J, Liu J, Post SR, Foroozesh M, Qin Z. Developing new ceramide analogs and identifying novel sphingolipid-controlled genes against a virus-associated lymphoma. Blood. 2020 Nov 5;136(19):2175-2187. doi: 10.1182/blood.2020005569. PubMed PMID: 32518949; PubMed Central PMCID: PMC7645984. 

 

Zhao M, Nanbo A, Becnel D, Qin Z, Morris GF, Li L, Lin Z. Ubiquitin Modification of the Epstein-Barr Virus Immediate Early Transactivator Zta. J Virol. 2020 Oct 27;94(22). doi: 10.1128/JVI.01298-20. Print 2020 Oct 27. PubMed PMID: 32847852; PubMed Central PMCID: PMC7592219. 

 

Faia C, Plaisance-Bonstaff K, Peruzzi F. In vitro models of HIV-1 infection of the Central Nervous System. Drug Discov Today Dis Models. 2020 Fall;32(Pt A):5-11. doi: 10.1016/j.ddmod.2019.10.007. Epub 2019 Dec 20. PubMed PMID: 33692833; PubMed Central PMCID: PMC7938360. 

 

Huynh-Le MP, Fan CC, Karunamuni R, Walsh EI, Turner EL, Lane JA, Martin RM, Neal DE, Donovan JL, Hamdy FC, Parsons JK, Eeles RA, Easton DF, Kote-Jarai Z, Amin Al Olama A, Benlloch Garcia S, Muir K, Grönberg H, Wiklund F, Aly M, Schleutker J, Sipeky C, Tammela TL, Nordestgaard BG, Key TJ, Travis RC, Pharoah PDP, Pashayan N, Khaw KT, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright LA, Brenner H, Schöttker B, Holleczek B, Park JY, Sellers TA, Lin HY, Slavov CK, Kaneva RP, Mitev VI, Batra J, Clements JA, Spurdle AB, Teixeira MR, Paulo P, Maia S, Pandha H, Michael A, Mills IG, Andreassen OA, Dale AM, Seibert TM. A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data. Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1731-1738. doi: 10.1158/1055-9965.EPI-19-1527. Epub 2020 Jun 24. PubMed PMID: 32581112; PubMed Central PMCID: PMC7483627. 

 

Chen J, Lin Z, Barrett L, Dai L, Qin Z. Identification of new therapeutic targets and natural compounds against diffuse intrinsic pontine glioma (DIPG). Bioorg Chem. 2020 Jun;99:103847. doi: 10.1016/j.bioorg.2020.103847. Epub 2020 Apr 13. PubMed PMID: 32311581; PubMed Central PMCID: PMC7260728. 

 

Singh P, Neumann DM. Persistent HCMV infection of a glioblastoma cell line contributes to the development of resistance to temozolomide. Virus Res. 2020 Jan 15;276:197829. doi: 10.1016/j.virusres.2019.197829. Epub 2019 Nov 29. PubMed PMID: 31790777; PubMed Central PMCID: PMC7357196. 

 

Plaisance-Bonstaff K, Faia C, Wyczechowska D, Jeansonne D, Vittori C, Peruzzi F. Isolation, Transfection, and Culture of Primary Human Monocytes. J Vis Exp. 2019 Dec 16;(154). doi: 10.3791/59967. PubMed PMID: 31885371; PubMed Central PMCID: PMC7610224. 

 

Rider PJF, Uche IK, Sweeny L, Kousoulas KG. Anti-viral immunity in the tumor microenvironment: implications for the rational design of herpes simplex virus type 1 oncolytic virotherapy. Curr Clin Microbiol Rep. 2019 Dec;6(4):193-199. doi: 10.1007/s40588-019-00134-3. Epub 2019 Nov 26. PubMed PMID: 33344108; PubMed Central PMCID: PMC7748056. 

 

Stalinska J, Houser L, Rak M, Colley SB, Reiss K, Jursic BS. Exploring anticancer activity of structurally modified benzylphenoxyacetamide (BPA); I: Synthesis strategies and computational analyses of substituted BPA variants with high anti-glioblastoma potential. Sci Rep. 2019 Nov 19;9(1):17021. doi: 10.1038/s41598-019-53207-0. PubMed PMID: 31745126; PubMed Central PMCID: PMC6864087. 

 

Zhang Y, Yuan F, Liu L, Chen Z, Ma X, Lin Z, Zou J. The Role of the miR-21/SPRY2 Axis in Modulating Proangiogenic Factors, Epithelial Phenotypes, and Wound Healing in Corneal Epithelial Cells. Invest Ophthalmol Vis Sci. 2019 Sep 3;60(12):3854-3862. doi: 10.1167/iovs.19-27013. PubMed PMID: 31529118; PubMed Central PMCID: PMC6881141. 

 

Del Valle L, Piña-Oviedo S. Human Polyomavirus JCPyV and Its Role in Progressive Multifocal Leukoencephalopathy and Oncogenesis. Front Oncol. 2019;9:711. doi: 10.3389/fonc.2019.00711. eCollection 2019. Review. PubMed PMID: 31440465; PubMed Central PMCID: PMC6694743. 

 

Stalinska J, Zimolag E, Pianovich NA, Zapata A, Lassak A, Rak M, Dean M, Ucar-Bilyeu D, Wyczechowska D, Culicchia F, Marrero L, Del Valle L, Sarkaria J, Peruzzi F, Jursic BS, Reiss K. Chemically Modified Variants of Fenofibrate with Antiglioblastoma Potential. Transl Oncol. 2019 Jul;12(7):895-907. doi: 10.1016/j.tranon.2019.04.006. Epub 2019 May 9. PubMed PMID: 31078963; PubMed Central PMCID: PMC6514324. 

 

Kheir F, Zhao M, Strong MJ, Yu Y, Nanbo A, Flemington EK, Morris GF, Reiss K, Li L, Lin Z. Detection of Epstein-Barr Virus Infection in Non-Small Cell Lung Cancer. Cancers (Basel). 2019 May 31;11(6). doi: 10.3390/cancers11060759. PubMed PMID: 31159203; PubMed Central PMCID: PMC6627930. 

 

Zhao M, Nanbo A, Sun L, Lin Z. Extracellular Vesicles in Epstein-Barr Virus' Life Cycle and Pathogenesis. Microorganisms. 2019 Feb 11;7(2). doi: 10.3390/microorganisms7020048. Review. PubMed PMID: 30754656; PubMed Central PMCID: PMC6406486. 

 

Fowlkes N, Clemons K, Rider PJ, Subramanian R, Wakamatsu N, Langohr I, Kousoulas KG. Factors Affecting Growth Kinetics and Spontaneous Metastasis in the B16F10 Syngeneic Murine Melanoma Model. Comp Med. 2019 Feb 1;69(1):48-54. doi: 10.30802/AALAS-CM-18-000036. Epub 2018 Dec 18. PubMed PMID: 30563585; PubMed Central PMCID: PMC6382051. 

 

Mills KL, Gomes AM, Standlee CR, Rojo MD, Carmeliet P, Lin Z, Machado HL. Gas6 is dispensable for pubertal mammary gland development. PLoS One. 2018;13(12):e0208550. doi: 10.1371/journal.pone.0208550. eCollection 2018. PubMed PMID: 30533018; PubMed Central PMCID: PMC6289431. 

 

Hossain F, Sorrentino C, Ucar DA, Peng Y, Matossian M, Wyczechowska D, Crabtree J, Zabaleta J, Morello S, Del Valle L, Burow M, Collins-Burow B, Pannuti A, Minter LM, Golde TE, Osborne BA, Miele L. Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways. Front Oncol. 2018;8:575. doi: 10.3389/fonc.2018.00575. eCollection 2018. PubMed PMID: 30564555; PubMed Central PMCID: PMC6289043. 

 

Vashistha H, Marrero L, Reiss K, Cohen AJ, Malhotra A, Javed T, Bradley A, Abbruscato F, Giusti S, Jimenez A, Mehra S, Kaushal D, Giorgio M, Pelicci PG, Kakoki M, Singhal PC, Bunnell B, Meggs LG. Aging phenotype(s) in kidneys of diabetic mice are p66ShcA dependent. Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1833-F1842. doi: 10.1152/ajprenal.00608.2017. Epub 2018 Sep 12. PubMed PMID: 30207172; PubMed Central PMCID: PMC6336986. 

 

Dai L, Zhao M, Jiang W, Lin Z, Del Valle L, Qin Z. KSHV co-infection, a new co-factor for HPV-related cervical carcinogenesis?. Am J Cancer Res.2018;8(11):2176-2184. eCollection 2018. Review. PubMed PMID: 30555737; PubMed Central PMCID: PMC6291645. 

 

Dai L, Chen J, Cao Y, Del Valle L, Qin Z. Ribonucleotide Reductase Inhibitor 3-AP Induces Oncogenic Virus Infected Cell Death and Represses Tumor Growth. J Cancer. 2018;9(23):4503-4509. doi: 10.7150/jca.27437. eCollection 2018. PubMed PMID: 30519356; PubMed Central PMCID: PMC6277659. 

 

Aydin Y, Stephens CM, Chava S, Heidari Z, Panigrahi R, Williams DD, Wiltz K, Bell A, Wilson W, Reiss K, Dash S. Chaperone-Mediated Autophagy Promotes Beclin1 Degradation in Persistently Infected Hepatitis C Virus Cell Culture. Am J Pathol. 2018 Oct;188(10):2339-2355. doi: 10.1016/j.ajpath.2018.06.022. Epub 2018 Aug 1. PubMed PMID: 30075149; PubMed Central PMCID: PMC6168955. 

 

Ungerleider N, Concha M, Lin Z, Roberts C, Wang X, Cao S, Baddoo M, Moss WN, Yu Y, Seddon M, Lehman T, Tibbetts S, Renne R, Dong Y, Flemington EK. The Epstein Barr virus circRNAome. PLoS Pathog. 2018 Aug;14(8):e1007206. doi: 10.1371/journal.ppat.1007206. eCollection 2018 Aug. PubMed PMID: 30080890; PubMed Central PMCID: PMC6095625. 

 

Dai L, Del Valle L, Miley W, Whitby D, Ochoa AC, Flemington EK, Qin Z. Transactivation of human endogenous retrovirus K (HERV-K) by KSHV promotes Kaposi's sarcoma development. Oncogene. 2018 Aug;37(33):4534-4545. doi: 10.1038/s41388-018-0282-4. Epub 2018 May 10. PubMed PMID: 29743595; PubMed Central PMCID: PMC6195842. 

 

Qiao J, Cao Y, Zabaleta J, Yang L, Dai L, Qin Z. Regulation of Virus-Associated Lymphoma Growth and Gene Expression by Bacterial Quorum-Sensing Molecules. J Virol. 2018 Jul 15;92(14). doi: 10.1128/JVI.00478-18. Print 2018 Jul 15. PubMed PMID: 29743366; PubMed Central PMCID: PMC6026753. 

 

Dai L, Smith CD, Foroozesh M, Miele L, Qin Z. The sphingosine kinase 2 inhibitor ABC294640 displays anti-non-small cell lung cancer activities in vitro and in vivo. Int J Cancer. 2018 May 15;142(10):2153-2162. doi: 10.1002/ijc.31234. Epub 2018 Jan 4. PubMed PMID: 29277894; PubMed Central PMCID: PMC5867242. 

 

Lassak A, Dean M, Wyczechowska D, Wilk A, Marrero L, Trillo-Tinoco J, Boulares AH, Sarkaria JN, Del Valle L, Peruzzi F, Ochoa A, Reiss K. Molecular and Structural Traits of Insulin Receptor Substrate 1/LC3 Nuclear Structures and Their Role in Autophagy Control and Tumor Cell Survival. Mol Cell Biol. 2018 May 15;38(10). doi: 10.1128/MCB.00608-17. Print 2018 May 15. PubMed PMID: 29483302; PubMed Central PMCID: PMC5954195. 

 

Dai L, Qiao J, Del Valle L, Qin Z. KSHV co-infection regulates HPV16+ cervical cancer cells pathogenesis in vitro and in vivo. Am J Cancer Res.2018;8(4):708-714. eCollection 2018. PubMed PMID: 29736315; PubMed Central PMCID: PMC5934560. 

 

Dai L, Bai A, Smith CD, Rodriguez PC, Yu F, Qin Z. ABC294640, A Novel Sphingosine Kinase 2 Inhibitor, Induces Oncogenic Virus-Infected Cell Autophagic Death and Represses Tumor Growth. Mol Cancer Ther. 2017 Dec;16(12):2724-2734. doi: 10.1158/1535-7163.MCT-17-0485. Epub 2017 Sep 22. PubMed PMID: 28939554; PubMed Central PMCID: PMC5716930. 

 

Li M, Li X, Zhuang Y, Flemington EK, Lin Z, Shan B. Induction of a novel isoform of the lncRNA HOTAIR in Claudin-low breast cancer cells attached to extracellular matrix. Mol Oncol. 2017 Dec;11(12):1698-1710. doi: 10.1002/1878-0261.12133. Epub 2017 Oct 30. PubMed PMID: 28846832; PubMed Central PMCID: PMC5709615. 

 

Dai L, Lin Z, Jiang W, Flemington EK, Qin Z. Lipids, lipid metabolism and Kaposi's sarcoma-associated herpesvirus pathogenesis. Virol Sin. 2017 Oct;32(5):369-375. doi: 10.1007/s12250-017-4027-2. Epub 2017 Oct 10. Review. PubMed PMID: 29019168; PubMed Central PMCID: PMC5869022. 

 

Pianovich NA, Dean M, Lassak A, Reiss K, Jursic BS. Anticancer potential of aminomethylidene-diazinanes I. Synthesis of arylaminomethylidene of diazinetriones and its cytotoxic effects tested in glioblastoma cells. Bioorg Med Chem. 2017 Oct 1;25(19):5068-5076. doi: 10.1016/j.bmc.2017.08.020. Epub 2017 Aug 12. PubMed PMID: 28864149; PubMed Central PMCID: PMC5870872. 

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