COBRE Junior Investigator
Department of Pharmacology and Experimental Therapeutics
Cardiovascular Center of Excellence
LSUHSC – New Orleans
Dr. Eric Lazartigues, Assistant Professor, received his Bachelor of Sciences in 1993 from the University Paul Sabatier of Sciences in Toulouse, France. His M.S. was awarded in 1994 from the University of Pharmacy Claude Bernard of Lyon, France. He received his Ph.D. from the University Paul Sabatier of Sciences in Toulouse in 1999. He completed his postdoctoral work at The University of Iowa School of Medicine in the Department of Anatomy & Cell Biology under the mentorship of Dr. Robin L. Davisson. Dr. Lazartigues joined the Department of Pharmacology at LSU Health Sciences Center in August 2005.
CoBRE Research Summary:
Dr. Lazartigues’ research focuses on understanding the role of the brain in regulating blood pressure and the development of hypertension. Angiotensin-II is a hormone that can increase blood pressure by acting in the brain and on blood vessels. Current strategies for the treatment of hypertension and other cardiovascular diseases use drugs that are designed to block the formation and actions of Angiotensin-II. Recently, a new enzyme, named ACE2, has been discovered which helps to degrade Angiotensin-II, therefore offering a new possibility for the treatment of cardiovascular diseases. Dr. Lazartigues’ group was the first to identify the presence of ACE2 in the brain. His CoBRE project focuses on understanding the importance of ACE2 in the brain and how this new enzyme alters the angiotensin system during the development of hypertension and other cardiovascular diseases.