Ashok Pullikuth, PhD
Ashok Pullikuth, PhD
Research Instructor of Pharmacology
Research Instructor of Pharmacology
Academic Office
Department of Pharmacology LSUHSC School of Medicine-New Orleans 1901 Perdido Street MEB#5208 New Orleans, Louisiana70112 Phone: (504) 568-2795 Fax: (504) 568-2361 Email: apulli@lsuhsc.edu
Laboratory:
Department of Pharmacology LSUHSC School of Medicine-New Orleans Medical Education Bldg #5238 1901 Perdido Street New Orleans, Louisiana70112 Phone: (504) 568-2223
Degrees
PhD (1998) University of California, Riverside, California, USA
Bio
Assistant Professor Research-Neuroscientist/Cell Biologist (2001-2003): Department of Cell Biology and Neuroscience, University of California, Riverside, California92521, USA
Instructor-Research (2008 - ): Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, School of Medicine, New Orleans, Louisiana 70112, USA
Postdoctorates:
1998: Departments of Cell Biology and Neuroscience and Entomology, University of California, Riverside92521, California, USA
1998-2001: Department of Biochemistry and Molecular Biology, Saint Louis University, School of Medicine, Saint Louis, Missouri, USA
2003-2007: Department of Pharmacology and Experimental Therapeutics, LouisianaStateUniversityHealthSciencesCenter, New Orleans, Louisiana, USA
Academic Memberships:
Associate Member: Sigma Xi
Member: Gamma Sigma Delta, Honor Society
Member: New YorkAcademy of Sciences
Member: American Society of Cell Biology
Member: American Association for the Advancement of Sciences (AAAS)
Consultant:
Human Protein Reference Database (HPRD), Institute of Bioinformatics and JohnsHopkinsUniversity: Trafficking GTPases and ATPases (www.hprd.org and www.ncbi.nlm.nih.gov/pubmed/14681466)
Research Interests
1) Reciprocal Regulation of Trafficking and Signaling
2) Cell Biology of Signaling Scaffolds
3) Nodes of Signal Integration in RTKs and GTPases Signaling
Teaching Activities
Advanced Nursing Pharmacology
Dental Pharmacology
Nursing Pharmacology
Selected Publications
Pullikuth, A. K., and Weidman, P. J. (2002). In vitro transport on cis and trans sides of the Golgi involves two distinct types of coatomer and ADP-ribosylation factor-independent transport intermediates. Journal of Biological Chemistry 277, 50355-50364.
Pullikuth, A. K., and Gill, S. S. (2002). In vivo membrane trafficking role for an insect N-ethylmaleimide-sensitive factor which is developmentally regulated in endocrine cells. Journal of Experimental Biology 205, 911-926.
Zhuang, M., Oltean, D. I., Gomez, I., Pullikuth, A. K., Soberon, M., Bravo, A., and Gill, S. S. (2002). Heliothis virescens and Manduca sexta lipid rafts are involved in Cry1A toxin binding to the midgut epithelium and subsequent pore formation. Journal of Biological Chemistry 277, 13863-13872.
Pullikuth, A. K., Filippov, V., and Gill, S. S. (2003). Phylogeny and cloning of ion transporters in mosquitoes. Journal of Experimental Biology 206, 3857-3868.
Pullikuth, A., McKinnon, E., Schaeffer, H. J., and Catling, A. D. (2005). The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals. Molecular and Cellular Biology 25, 5119-5133.
Pullikuth, A. K., K. Aimanova, W. Kang’ethe, H. R. Sanders, and S.S. Gill. (2006). Molecular characterization of sodium/proton exchanger 3 (NHE3) from the yellow fever vector, Aedes aegypti. Journal of Experimental Biology209: 3529-3544.
Kang’ethe, W. K., K. Aimanova, S. S. Gill and A. K. Pullikuth . (2007). NHE8 mediates amiloride sensitive Na+/H+ exchange across Malpighian tubules and catalyzes Na+ And K+ transport in reconstituted proteoliposomes. American Journal of Physiology- Renal Physiology 292: 1501-1512
Pullikuth, A. K., and A. D. Catling (2007). Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: A prespective. Cellular Signalling 19: 1621-1632
Park, E. R., A. K. Pullikuth, E. M. Bailey, D. E. Mercante, and A. D Catling. 2009.Differential requirement for MEK Partner 1 in DU145 prostate cancer cell migration. Cell Communication and Signaling, 7:26 (doi:10.1186/1478-811X-7-26)
Hu S, Delorme N, Liu Z, Liu T, Velasco-Gonzalez C, Garai J, Pullikuth A, and Koochekpour S. 2010. Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion. Molecular Cancer. Feb 4;9(1):30.
Pullikuth, A. K., and A.D. Catling. 2010. Extracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP. Molecular and Cellular Biology, 30(13): 3233-3248.

myLSUHSC