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Daniel Kapusta, PhD
School of Medicine
Pharmacology
Primary Research / Clinical / Teaching Interests:
research focus: central neural and humoral control of cardiovascular and renal function; role of GPCR G-alpha subunit pathways in neurohumoral control of heart, vascular and kidney function
teaching: Physiology-Pharmacology-Pathology of the nervous system, cardiovascular and kidney function, hypertension and fluid/electrolyte pathology
Therapeutic development of novel water diuretics (aquaretics)
Secondary Research / Clinical / Teaching Interests:
Development of novel treatments for prevention of acute renal failure and acute tubular necrosis
Pharmacological treatment of multiorgan failure in trauma
Unique Techniques Used or Developed:
Combination of methods for investigating cardiovascular and kidney function in vivo with approaches to study cell/molecular signaling pathways at the tissue/cell level
Unique Equipment Used:
Methods for direct recording of multifiber sympathetic nerve activity, stereotaxic brain microinjection, radio-telemetry methods for chronic measurement of cardiovascular function
Keywords Associated with Work:
angiotensin II
autonomic nervous system
brain microinjection
cardiovascular
central nervous system
endorphins, opioid peptides
kidney
renal sympathetic nerve
vasopressin, renin/angiotensin, aldosterone
Last Updated: 01/24/2017
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