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Faculty Interests Database

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Disciplines and Occupations
   Natural Science Disciplines
         Science
               Research
                     Biomedical Research
                           Translational Research

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Frederick Brazda, MD
Pathology / Cardiovascular Center of Excellence
Primary Research / Clinical / Teaching Interests:
Translational Research
Secondary Research / Clinical / Teaching Interests:

Clinical Chemistry Tests
Unique Techniques Used or Developed:
Unique Equipment Used:
Keywords Associated with Work:
Delivery of Health Care, Integrated
Information Science
Last Updated: 01/24/2017



Traci Goodchild, PhD
Cardiovascular Center of Excellence
Primary Research / Clinical / Teaching Interests:
Angiogenesis Inducing Agents
Atherosclerosis
Hydrogen Sulfide
Myocardial Ischemia
Myocardial Reperfusion Injury
Nitric Oxide
Preclinical GLP Studies
Stem Cell Research
Translational Research
Secondary Research / Clinical / Teaching Interests:
B Cells
Biological Scaffolds
Critical Limb Ischemia (CLI)
Drug-Eluting Stents
Immunohistochemistry
Peripheral Artery Disease (PAD)
Plastic Embedding
Unique Techniques Used or Developed:
Acute Myocardial Ischemia in Swine
Blood Pressure Telemetry in Swine (DSI)
Heart Failure with Preserved Ejection Fraction (HFpEF) in Rats (in development)
Heart Failure with Preserved Ejection Fraction (HFpEF) in Swine (in development)
Heart Failure with Reduced Ejection Fraction (HFrEF) in Rats
Heart Failure with Reduced Ejection Fraction (HFrEF) in Swine
Intramyocardial Stem Cell Injections via Intracardiac Echo (ICE) Guidance
Percutaneous (Non-Surgical) Large Animal Model of Peripheral Artery Disease (PAD)
Unique Equipment Used:
Biosense Webster NOGA Cardiac Navigation System
Digital Telemetry System (DSI) for Large Animals
GE 4D Logiq E9 Ultrasound System
GE MacLab/CardioLab Hemodynamic Acquisition and Recording System
GE Optima Innova Cath Lab for Animal Research
Medrad Mark 7 Power Injection System
St. Jude Medical ILUMIEN OCT and FFR System
Volcano Virtual-Histology Intravascular Ultrasound (VH-IVUS)
Keywords Associated with Work:
Adult Stem Cells
Angiography
Angioplasty, Balloon, Coronary
B Cells
Catheter Ablation
Coronary Angiography
Heart Failure
Hematopoietic Stem Cells
Hydrogen Sulfide
Myocardial Ischemia
Nitric Oxide
Nitric Oxide Synthase
Receptors, Endothelin
Sus scrofa
Swine
Swine, Miniature
Last Updated: 06/22/2017



Sunyoung Kim, PhD
Biochemistry
Primary Research / Clinical / Teaching Interests:
Allostery
ATP hydrolysis
Evolution of protein function
Kinesin
Mitosis
Motor protein
Proteomics
Secondary Research / Clinical / Teaching Interests:
Unique Techniques Used or Developed:
reaction-induced infrared spectroscopy
Structural biomarkers
Unique Equipment Used:
Bruker FTIR Spectrophotometer Suite with NdYAG Lazer
High-throughput biochemical assays
Infrared spectrometer
Neural Networks (Computer)
Keywords Associated with Work:
Biophysics
Enzymes
Individualized Medicine
Prognosis
Translational Research
Last Updated: 01/24/2017



David Lefer, PhD
Cardiovascular Center of Excellence
Grant Review Committees Served on:   NIH     Other Committees  
Primary Research / Clinical / Teaching Interests:
Cardiovascular Pathology
Cardiovascular Physiology
Hydrogen Sulfide Signaling
Nitric Oxide Signaling
Renal Denervation
Translational Research
Secondary Research / Clinical / Teaching Interests:
Antioxidant Therapy
Fibrosis
Metabolomics
Mitochondria, Heart
Neprilysin
Unique Techniques Used or Developed:
Hydrogen Sulfide Measurement by Gas Chromatography Chemiluminescence
Model - Mouse Myocardial Infarct Induced Heart Failure
Model - Mouse Myocardial Ischemia Reperfusion Injury
Model - Mouse Transaortic Constriction (TAC) Left Ventricular Hypertrophy
Model - Rat Myocardial Infarct Induced Heart Failure
Model - Rat Myocardial Ischemia Reperfusion Injury
Model - Swine Myocardial Infarct Induced Heart Failure
Model - Swine Myocardial Ischemia Reperfusion Injury
Nitrite/Nitric Oxide Metabolite Measurement by Ion Chromatography
Unique Equipment Used:
Ex Vivo Vascular Reactivity Radnoti Organ Bath Chambers (16)
Gas Chromatography Chemiluminescence for Plasma and Tissue Hydrogen Sulfide
Ion Chromatography (ENO20 Analyzer, Eicom) for Plasma and Tissue Nitrite
Li-Cor Odyssey CLx Imaging System
Microsurgical Procedural Stations (10) for Mice
Millar Pressure Catheter/Hemodynamic Systems for Mice
Millar Pressure Catheter/Hemodynamic Systems for Rats
Surgical Procedural Stations (5) for Rats
Visual Sonics Vivo 2100 for Mice
Visual Sonics Vivo 2100 for Rats
Visual Sonics Vivo 2100 Workstations (3)
Keywords Associated with Work:
Cardiovascular Agents
Cardiovascular Physiological Processes
Cardiovascular System
Diabetes Mellitus, Experimental
Heart Failure
Hydrogen Sulfide
Metabolic Syndrome X
Models, Cardiovascular
Myocardial Ischemia
Myocardial Reperfusion Injury
Nitric Oxide
Nitric Oxide Donors
Nitric Oxide Synthase
Nitrite Reductases
Prostaglandin Antagonists
Renal Denervation
Simvastatin
Sodium Nitrite
Statin Therapy
Transaortic Constriction (TAC) Mouse Model
Last Updated: 06/22/2017