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Daniel
Kapusta,
PhD
School of Medicine
Pharmacology
DKAPUS@lsuhsc.edu
Keywords Associated with Work
angiotensin II
autonomic nervous system
brain microinjection
cardiovascular
central nervous system
endorphins, opioid peptides
kidney
renal sympathetic nerve
vasopressin, renin/angiotensin, aldosterone
Primary Research / Clinical / Teaching Interests
research focus: central neural and humoral control of cardiovascular and renal function; role of GPCR G-alpha subunit pathways in neurohumoral control of heart, vascular and kidney function
teaching: Physiology-Pharmacology-Pathology of the nervous system, cardiovascular and kidney function, hypertension and fluid/electrolyte pathology
Therapeutic development of novel water diuretics (aquaretics)
Secondary Research / Clinical / Teaching Interests
Development of novel treatments for prevention of acute renal failure and acute tubular necrosis
Pharmacological treatment of multiorgan failure in trauma
Unique Equipment Used
Methods for direct recording of multifiber sympathetic nerve activity, stereotaxic brain microinjection, radio-telemetry methods for chronic measurement of cardiovascular function
Unique Techniques Used or Developed
Combination of methods for investigating cardiovascular and kidney function in vivo with approaches to study cell/molecular signaling pathways at the tissue/cell level
Last Updated: 01/24/2017
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