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Medicine
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LSU
Patient Care
Tuesday, December 10, 2024 9:00 PM | 63°F
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Dennis
Paul,
PhD
School of Medicine
School of Dentistry
Pharmacology
DPAUL@lsuhsc.edu
CV / Bio:
https://orcid.org/0000-0003-4858-5450
Keywords Associated with Work
Pain
Primary Research / Clinical / Teaching Interests
Analgesia
Carcinoma
We have developed a novel treatment for cancers that overexpress voltage-gated sodium channels. We stimulate the VGSCs using a pulsed electric field, while simultaneously pharmacologically blocking sodium pumps. By overloading the cancer cells with sodium, we cause an osmotic lysis. Non-cancerous cells, with fewer VGSCs, do not lyse.
Neoplasms by Histologic Type
metastatic carcinoma lysis
Receptors, Opioid
Receptors, Opioid, delta
Receptors, Opioid, mu
Unique Equipment Used
Mettler MT5
micro balance MEB 5112 Contact Person: Dennis Paul see contact person for orientation and training
Last Updated: 03/27/2024
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