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Faculty Interests Database

Jeffrey Gidday, PhD

School of Medicine
Ophthalmology / Physiology

Grant Review Committees Served on:   NIH     Other Committees  


Keywords Associated with Work Epigenetics
Intermittent hypoxia
Neuroprotection assessed functionally and morphologically
Retinal Diseases neuroprotection
Stroke neuroprotection
Primary Research / Clinical / Teaching Interests Retinal Diseases epigenetic approaches to retinal protection - mechanisms and therapeutics mouse models of glaucoma and other retinopathies
Secondary Research / Clinical / Teaching Interests Stroke epigenetic approaches to neurovascular protection - mechanisms and therapeutics mouse models of stroke
Unique Equipment Used In vivo studies in mouse models of retinal degenerative diseases We use a variety of experimental approaches in our studies, including in vivo functional and structural assessments of retinal physiology by ERG and OCT, respectively. Immunohistochemistry, other molecular biological methods employed in wild-type and mutant mice.
Unique Techniques Used or Developed stress conditioning (hypoxia) as a neuroprotective therapeutic for retinal disease using systemic hypoxia as an epigenetic stimulus for neuroprotection in glaucoma and other neurodegenerative diseases of the retina Using functional and structural metrics of retinal injury/protection by electroretinography and optical coherence tomography mechanisms of transgenerational epigenetics; DNA methylation and bioinformatic analyses
Last Updated: 08/16/2017