PhD - 1986
MD - 1988
A native of Chicago, Dr. Hagensee earned his MD and PhD from Baylor College of Medicine in Houston. He completed an internal medicine residency and a fellowship in infectious diseases at University of Washington Affiliated Hospitals in Seattle, Washington. From 1994 to 1996, he was a post-doctoral fellow at the Fred Hutchinson Research Center and an instructor in the division of Infectious diseases at the University of Washington Affiliated Hospital. He joined the faculty of LSU School of Medicine in 1996 as an assistant professor in the section of infectious diseases.
The Hagensee laboratory studies the role of human papillomavirus (HPV) in human malignancies. Studies are focused on the increase in HPV-related cervical cancer in HIV+ women and the increase in oral cancer in HIV+ men and women.
A new area of focus is the role of HPV in anal cancer from basic biology to clinical trials and similar increases in anal cancer rates in HIV+ individuals. This increase may be due, in part, to an interaction with another DNA virus, Epstein Barr Virus (EBV) which also causes human cancers. Current projects include detection of HPV and EBV in clinical specimens, determination of the systemic and local immune response against each virus, in-vitro modeling techniques and development of xenograft mouse models. Results from these studies will aid in improved diagnostics and preventive measures for these cancers. Additional projects include development of self-testing methods to detect HPV DNA to improve cervical cancer screening and studies into improvement of HPV vaccine implementation.
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Research Endowment Fund Review Committee
Hagensee, Michael E. in Current diagnosis and Treatment: Sexually Transmitted Diseases, Chapter 29. Management of Abnormal Pap Smears pg 204-213; Klausner, JD and Hook, ED eds, McGraw Hill Companies, Inc. 2007
Cameron, Jennifer E., and Hagensee, Michael E., in Aids-Associated Viral Oncogenesis: Chapter 7: Human Papillomavirus Infection and Disease in the HIV+ Individual, pg 185-214; Meyers, C. editor, Springer Science+ Business Media, LLC, 233 Spring Street, New York, NY, 10013, USA. 2007
Dunne, E.F., Nielson, C.M., Hagensee, M.E., Papenfuss, M.R., Harris, R.B., Herrel, N., Gourlie, J., Abrahamsen, M., Markowitz, L.E., Giuliano, A.R. HPV 6/11, 16, 18 seroprevalence in men in two US cities. Sex Transm Dis. Nov;36(11):671-4. 2009.
Clark, RA. and M.E. Hagensee Human papilloma virus infections and disease in HIV. HIV. Clin. 21:3-5. 2009.
Cameron, J.E., and Hagensee, M.E., Oral HPV Complications in HIV-infected Patients. Current HIV/AIDS Reports. 5:126-131, 2008.
Cameron, J. E. and Hagensee M.E., Human papillomavirus infection and disease in the HIV+ individual. Cancer Treat. Res. 133:185-213. 2007.