Dr. Eric Lazartigues and his colleague Dr. Catalin Filipeanu (Howard University) were awarded a new 4-year R01 from NHLBI to study ACE2 downregulation in hypertension (1/2020).
Dr. Eric Lazartigues' lab publications (2019):
- Dr. Sodhi: A Dynamic Variation of Pulmonary ACE2 Is Required To Modulate Neutrophilic Inflammation in Response to Pseudomonas aeruginosa Lung Infection in Mice. (11/2019)
- Dr. Snigdha Mukerjee : ACE2 and ADAM17 Interaction Regulates the Activity of Presympathetic Neurons. (11/2019)
- Dr. Jiaxi Xu : Activation of ADAM17 (A Disintegrin and Metalloprotease 17) on Glutamatergic Neurons Selectively Promotes Sympathoexcitation. (6/2019)
- Dr. Snigdha Mukerjee : Next-Generation Tools to Study Autonomic Regulation In Vivo. (2/2019)
Dr. Charles Nichols had his research published in the following article:
Dr. Charles Nichols participated in an ASPET symposium in April 2019 and his research is featured in the ASPET newsletter here:
Ms. Snigdha Mukerjee was awarded the Caroline Tum Suden. Frances A. Hellebrandt Professional Opportunity Award by the Women in Science committee. She also received the Poster Trainee Award from the CNS section of the American Physiological Society. The Awards and prizes were confered to her at the Experimental Biology meeting in Orlando, FL.
Dr. Jiaxi Xu was awarded the Caroline Tum Suden. Frances A. Hellebrandt Professional Opportunity Award by the Women in Science committee. The Award and prize were confered to her at the Experimental Biology meeting in Orlando, FL.
Dr. Thomas Flanagan, in Dr. Nichols’ lab, received a First Place, Postdoctoral Poster Award, from the ASPET Division for Translational and Clinical Pharmacology, at the Experimental Biology Meeting in April 2019. The title of Dr. Flanagan’s presentation was “Therapeutic Effects of 5-HT2A Receptor Activation in a Murine Ovalbumin-Induced Chronic Asthma Model.”
Dr. Mungrue received an award for his R21 grant, “Proof of principle for a scalable multiplex proteome quantitation technology” from the National Institute of General Medicine.
Dr. Eric Lazartigues received notice that his grant application to the American Diabetes Association “Epigenetic modulation of the autonomic nervous system and its consequences for cardio-metabolic diseases” will be funded for 3 years starting in January 2019.
Dr. Eric Lazartigues' lab members publications (2018):
- Ms. Snigdha Mukerjee: Next generation tools to study in vivo autonomic regulation. (12/2018)
- Dr. Tyler Basting: Glutamatergic neurons of the paraventricular nucleus are critical contributors to the development of neurogenic hypertension. (8/2018)
Dr. Josh Oakes: Nicotine and the Renin-Angiotensin System.
- Ms. Carvalho-Galvao: Central administration of TRV027 improves baroreflex sensitivity and vascular reactivity in spontaneously hypertensive rats. (7/2018)
- Dr. Jiaxi Xu : Excessive Glutamate Stimulation Impairs ACE2 Activity Through ADAM17-Mediated Shedding in Cultured Cortical Neurons. (5/2018)
- Ms. Snigdha Mukerjee: Sympathetic nerve activity and neuro-inflammation: Who is in the driver's seat? (2/2018)
Dr. Martin Ronis has an article on his research published on Research Outreach:
Dr. Donna Neumann received an RO1 grant “CTCF mediated HSV-1 gene expression in latency and reactivation” awarded in Novemver 2018 by the National Institute of Allergy and Infectious Diseases. Dr. Neumann received 5 years of funding for this award.
Dr. Mark Nigles in Dr. Winsauer’s lab was awarded a NRSA F32 post-doctoral grant from National Institute of Drug Abuse, entitled, "Interaction of Cannabinoids and Opiods on Antinociception, Learning and Performance Behavior” that will begin in the Fall of 2018.
Dr. Tyler Basting in Dr. Lazartigues’ lab was awarded a NRSA F32 post-doctoral grant from National Heart , Lung and Blood Institute, entitled, "ADAM17 mediated arterial pressure regulation in conscious mice: an optogenetic study” that will begin on July 1st of 2018.
Dr. Wayne Backes is the new President-elect for ASPET (American Society for Pharmacology & Experimental Therapeutics) and will begin his term on July 1, 2018.
Dr. Jiaxi Xu in Dr. Lazartigues’ lab was distinguished with the American Physiological Society Michael J. Brody Young Investigator Award from the NCAR section (Experimental Biology meeting, San Diego, CA, April 21-25th, 2018).
Ms. Snigdha Mukerjee in Dr. Lazartigues’ lab was distinguished with the American Physiological Society Data Sciences Outstanding Graduate Student Award from the NCAR section (Experimental Biology meeting, San Diego, CA, April 21-25th, 2018).
Dr. Donna Neumann was notified in March 2018 that her most recent paper “Depletion of the Insulator Protein CTCF Results in Herpes Simplex Virus 1 Reactivation In Vivo “ has been selected as a Spotlight Feature in the Journal of Virology.
Shannon Washington (Dr. Neumann's Lab) was accepted into the Intramural NIAID Research Opportunities (NIRO) program at NIH. INRO is a 4-day program for academically talented students from underrepresented groups in science who wish to learn more about NIAID and are interested in exploring career opportunities in allergy, immunology, and infectious diseases. The INRO program is highly competitive with only 18 and 20 students being accepted into the program.
Dr. James Watt in Dr. Ronis’ lab was awarded a F32 fellowship from NIAAA, entitled, "Identifying the role of reactive oxygen species in alcohol-induced murine growth plate pathology” that will begin in the Fall of 2017.
Dr. Juan Gao was awarded a LA CaTS Center Road Map Scholar Grant in June 2017. Dr. Gao will be enrolled in a Master's of Clinical Science degree program.
Dr. Eric Lazartigues' lab members publications (2017):
- Dr. Jiaxi Xu and Dr. Srinivas Sriramula: Clinical Relevance and Role of Neuronal AT1 Receptors in ADAM17-Mediated ACE2 Shedding in Neurogenic Hypertension. (5/2017)
- Ms. Snigdha Mukerjee : Perinatal exposure to Western diet programs autonomic dysfunction in the male offspring. (5/2017)
- Dr. Kim Pedersen and Dr. Harshita Chodavarapu: Forkhead box transcription factors of the FOXA class are required for basal transcription of ACE2. (4/2017)
- Dr. Tyler Basting :DOCA-Salt hypertension: An update. (3/2017)
- Dr. Srinivas Sriramula and Dr Kim Pedersen: Determining the Enzymatic Activity of Angiotensin-Converting Enzyme 2 (ACE2) in Brain Tissue and Cerebrospinal Fluid Using a Quenched Fluorescent Substrate. (2/2017)
Dr. Charles Nichols' lab had a publication featured in a writeup on Chemical and Engineering News website in March:
Dr. Wayne Backes' RO1 grant entitled "Interactions among P450 system proteins and their distribution into endoplasmic reticulum micordomains" was renewed for NIH funding for four more years in March 2017.
Dr. Eric Lazartigues is part of a multiple PI team, including Dr. Xinping Yue and Dr. Jason Gardner, who received a new R01 from NHLBI, entitled “Chronic nicotine inhalation increases susceptibility to cardiovascular and pulmonary diseases through inhibition of local compensatory mechanisms”
David Polhemus (Dr. Lefer's Lab) was selected in February 2017 by the editorial board of Circulation Research to be spotlighted as a early career trainee and will be interviewed about his research experience.
Dr. Jiaxi Xu received the Gordon Research Seminar Best Oral Presentation Award (Angiotensin Gordon Research Conference, Ventura, CA, February 18-23rd, 2018).
Ms. Harshita Chodavarapu has been selected to receive the American Physiological Society Endocrinology & Metabolism Research Recognition Award, (Experimental Biology meeting, Chicago, IL, April 22-26th, 2017).
Dr. Jiaxi Xu has been selected to receive the American Physiological Society NCAR membership-sponsored Experimental Biology Trainee Award (Experimental Biology meeting, Chicago, IL, April 22-26th, 2017).
Ms. Snigdha Mukerjee has been selected to receive the American Physiological Society Attoquant-sponsored Experimental Biology Trainee Award from the NCAR section (Experimental Biology meeting, Chicago, IL, April 22-26th, 2017).
Dr. Tracy Goodchild received funding for a Cardiovascular COBRE pilot project entitled "Therapeutic Potential of Renal Denervation and Stem Cells in Acute MI starting January 1, 2017.
Dr. Kurt Varner received the Ken Moore Distinguished Alumnus Award for 2016 at the 50 year Anniversary Celebration of the founding of the Department of Pharmacology and Toxicology at Michigan State University (MSU) this past September. The celebration included a symposium at which Dr. Varner gave a talk entitled, “Cardiovascular toxicity of environmentally persistent free radicals: a unique pollutant particle system.” Dr. Varner is the LSU Health Sciences Center SRP Leader of Project 4: Environmentally Persistent Free Radicals Increase Cardiac Vulnerability to Ischemia.
Dr. Martin Ronis' R01 grant entitled “The role of oxidative stress in alcohol-induced osteopenia” was recommended for conversion to a Method to Extend Research in Time (MERIT) Award by the National Advisory Council on Alcohol Abuse and Alcoholism and will convert to a 10 year award.
Dr. Charles Nichols was awarded a two-year R21 grant entitled “Drosophila to elucidate serotonin’s role in stimulant drug abuse”, from the National Institute of Drug Abuse.
Dr. Charles Nichols was awarded a major research contract from the Eleusis Benefit Corporation, for his project “Investigation of the anti-inflammatory effects of serotonin 5-HT2A receptor activation.”
Rebecca Crawford successfully defended her dissertation entitled “CHAC1 Positively Regulates Differentiation and Protein Synthesis in the Musculoskeletal System” in November 2016.
Kelly Jean Sherman successfully defended her dissertation entitled “The Comparative Effects of Methamphetamine and Lysergic Acid Diethylamide on Drosophila Behavior” in November 2016.
Shannan Washington was selected to present her work at the 2016 Chromatin Control of Viral Infection Workshop held at the National Institutes of Health Bethesda Campus in September, 2016.
Dr. Imran Mungrue received a Summer 2015 Innovative Research Grant entitled “ A novel method for Rapid Simultaneous Proteome Quantitation in Biological Samples,” from the American Heart Association. This 2 year award that will allow him to develop a new area of research in his lab.
Dr. Dennis Paul, Dr. Daniel Kapusta, Dr. Charles Nichols and Dr. Jeff Erickson were given Innovation Awards. These awards supported by the LSUHSC Office of Academic Affairs and the HSC Foundation were presented to these investigators in recognition of their receipt of patents, licensing agreements and/or LIFT grants over the last 3 years.
Dr. Donna Neumann and Dr. Imran Mungrue were each awarded a Leveraging Innovation for Technology Transfer (LIFT) grant from the LSU Board of Supervisors. Donna’s grant is entitled “Development of novel small molecule treatments for multi drug-resistant fungal infections”. Imran’s grant is “Proof of concept for a new product allowing proteome scale quantitation” These exciting highly competitive grants that were chosen by the Board of Supervisors on the basis of their innovation and commercial potential. It will be exciting to see these new projects develop.
Dr. Eric Lazartigues was promoted to Full Professor.
Dr. Charles Nichols was just selected to receive an American Asthma Foundation Scholar Grant Award for his work on the anti-inflammatory actions of 5-HT2A receptor agonists in asthma. This 2 year award was one of only 7 selected for funding by the Asthma Foundation from a pool of 138 applicants
Dr. Jiaxi “Jessie” Xu , received an American Heart Association Postdoctoral Fellowship Award. Dr. Xu joined Dr. Lazartigues’ laboratory this past winter and has made great progress with her project.
Dr. Andy Catling who just received word that our proposals to the LSU Board of Regents for the Superior Graduate Student Awards has been approved for this academic year and next academic year.
In addition to successfully defending his dissertation last week, Felix Nau has been rather busy getting ready for the upcoming Experimental Biology Meeting. We received notice that he has been awarded:- an ASPET Graduate Student Travel Award and -the Society for Experimental Biology and Medicine 2015 Young Investigator Award, and -his poster “Allergic Asthma and Serotonin 5-HT2 Receptor Activation: New Therapeutic Directions” was selected for the ASPET Best Abstract Competition.
Dr. Daniel Kapusta , won the Aesculapian Excellence in Teaching Award for the Spring semester of 2015.
Shannon Washington received a travel award to offset the cost of registration to the International Herpesvirus Workshop in Boise, Idaho.
Dr. Peter Winsauer received a new NIH RO1 grant.
Dr. Eric Lazartigues received the official notice that his RO-1 grant was renewed for an additional 4 years.
Shannon Washington received a travel award to attend and present her work at the 4th Chromatin Control of Viral Infections Workshop presented by the National Institute of Allergy and Infectious Diseases. This is a highly prestigious workshop that will be held on the NIH campus in September.
Congratulations Dr. Charles Nichols and Ms Indya Bruce on Indya’s third place finish in the Summer Research Internship Poster Symposium yesterday. Indya was a summer undergraduate research intern in Dr. Nichols’ lab congratulating Dr. Charles Nichols and Ms Indya Bruce on Indya’s third place finish in the Summer Research Internship Poster Symposium yesterday. Indya was a summer undergraduate research intern in Dr. Nichols’ lab.
Dr. Rob Reed was promotioed to Associate Professor.
Dr. Eugenia Prescott of Dr. Mungrue's lab was selected to attend the 2014 Postdoctoral Preparation Institute Workshop sponsored by the Federation of American Societies for Experimental Biology (FASEB)/Maximizing Access to Research Careers (MARC) Program.
Congrats to Dr. Juan Gao and Ms Kusma Pyakurel for receiving grant awards from the American Heart Association. Juan received a postdoctoral fellowship for her project “RVLM G-alpha12 Proteins and Neurogenic Hypertension in SHR“. Juan is conducting her study in Dr. Kapusta’s laboratory.
Kusma received a predoctoral fellowship for her project “Role of DNA-PK in Inflammation Independent of DNA-damage Repair in Atherogenesis,’ which she is conducting under the direction of Dr. Boulares.