Joseph M. Moerschbaecher, PhD


Current research includes two major areas of investigation. The first involves studies of various cannabinoid agonists and antagonists on the acquisition and performance of discriminations in monkeys. Research is also targeted towards characterizing the effects of cannabinoid agonists in combination with other abused drugs on learning and memory processes. The comparative pharmacology of cannabinoids in monkeys and rats is also under investigation in an attempt to elucidate differences in behavioral activity between the species. The second area of research involves characterizing both the acute and chronic effects of various benzodiazepines and atypical anxiolytic agents on learning and memory in monkeys. This research is targeted towards understanding the consequences of anxiolytic drug therapy on complex behavior processes.

Recent Publications

Winsauer, P.J., Lambert, P., and Moerschbaecher, J.M.: Cannabinoid ligands and their effects on learning and performance in rhesus monkeys. Behavioral Pharmacology, 10:497-511, 1999.

Nakamura-Palacios, E.M., Moerschbaecher, J.M., and Barker, L.A.: The pharmacology of SR141716A: A review. CNS Drug Review, 5:43-58, 1999.

Winsauer, P.J., Silvester, K.R., Moerschbaecher, J.M., and France, C.P.: Cocaine self-administration in monkeys: Effects on the acquisition and performance of response sequences. Drug and Alcohol Dependence, 59:51-61, 2000.

Winsauer, P. J. and Moerschbaecher, J. M.: Differential effects of 5-HT agonists and antagonists on the repeated acquisition and performance of response sequences in monkeys. Behavioural Pharmacology, 11: 535-553, 2000.

Winsauer, P. J., McCann, U. D., Yuan, J., Delatte, M. S., Stevenson, M. W., Ricaurte, G. A. and Moerschbaecher, J. M.: Effects of fenfluramine, m-CPP and triazolam on repeated acquisition in squirrel monkeys before and after neurotoxic MDMA admininstration. Psychopharmacology (in press).

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