2013 9:13:28 AM

Meng Luo, PhD

Instructor - Research

Office:
Medical Education Building
1901 Perdido Street, Room 3205T6
New Orleans, LA  70112
Phone:  (504) 568-6377

Microbial Genomics Resource Group Lab:
Clinical Science Research Building
533 Bolivar Street, Room 749
New Orleans, LA  70112
Phone:  (504) 568-3336

Email:mluo2@lsuhsc.edu

MGRG: http://metagenomics.lsuhsc.edu/mgrg/

Degrees

PhD in Crop Genetics and Breeding, 2001
Chinese Academy of Agricultural Science
Beijing, China

MS in Microbiology, 1996
Inner Mongolia University
China

BS in Botany, 1987
Inner Mongolia University
China

Bio

Dr. Luo received his Ph.D. in 2001 from Chinese Academy of Agricultural Science, Beijing, China. In 2002, he carried out postdoctoral studies at the University of Georgia, studying the effect of drought/high-temperature on Aspergillus infection and aflatoxin contamination in corn and peanuts using functional genomics techniques. In 2004, he was promoted to Research Assistant Scientist in the Crop and Soil Sciences Department. In 2008, he joined the Food and Feed Safety Institute as Postdoctoral Associate at the Southern Region Research Center of USDA-ARS, New Orleans to continue his interested studies using transcriptomics and proteomics techniques. 

Dr. Luo joined the LSUHSC in 2012 as Research Associate in the Genomics Core, and transferred to the Department of Microbiology, Immunology and Parasitology as Instructor in 2013.

Research Interests

Interaction between hosts and pathogens under environmental stress, focusing on the expression of defense related genes and proteins in hosts in response to biotic and abiotic stress.

Based on the analysis of microarrary and next-generation sequencing data, exploring the resistant mechanisms in hosts, and developing biomarker sets used for assessment and selection of resistant genotypes in the complex phenotypes controlled by multiple genes.

Current research: microbiome and mycobiome in human, animals and environments using the next-generation sequencing platform of Illumina MiSeq and NextSeq; variants' identification of viruses.

NGS technical service: 16S rRNA, ITS, small genome, CHIP, small RNA, RNA-seq.   

Selected Publications
  1. Goldsmith F, Guice J, Page R, Welsh DA, Taylor CM, Blanchard EE, Luo M, Raggio AM, Stout RW, Carvajal-Aldaz D, Gaither A, Pelkman C, Ye J, Martin RJ, Geaghan J, Durham HA, Coulon D, Keenan MJ. Obese ZDF rats fermented resistant starch with effects on gut microbiota but no reduction in abdominal fat. Mol Nutr Food Res. 2017. 61(1). PMID: 27234399.
  2. He B, Hoang TK, Wang T, Ferris M, Taylor CM, Tian X, Luo M, Tran DQ, Zhou J, Tatevian N, Luo F, Molina JG, Blackburn MR, Gomez TH, Roos S, Rhoads JM, and Liu Y.  Resetting microbiota by Lactobacillus reuteri inhibits T reg deficiency-induced autoimmunity via adenosine A2A receptors. J. Exp. Med. 214 (1): 107-123, 2017. PMID: 27994068.
  3. DR Samuelson, TP Charles, NM de la Rua, CM Taylor, EE Blanchard, M Luo, JE Shellito, DA Welsh.  Analysis of the intestinal microbial community and inferred functional capacities during the host response to Pneumocystis pneumonia.  Exp Lung Res.  2016. 7:1-15.  PMID: 27925857. 
  4. Samuelson DR, de la Rua NM, Charles TP, Ruan S, Taylor CM, Blanchard EE, Luo M, Ramsay AJ, Shellito JE, Welsh DA. Oral Immunization of Mice with Live Pneumocystis murina Protects against Pneumocystis Pneumonia. J Immunol. 2016. 196(6):2655-65. PMID: 26864029.
  5. Bruce-Keller A.J., Salbaum J.M., Luo M., Blanchard IV E., Taylor C.M., Welsh D.A. & Berthoud H.R. 2014. Obese-type Gut Microbiota Induce Neurobehavioral Changes in the Absence of Obesity.  Biol Psychiatry, 3223(14), 520-524. PMID: 25173628.
  6. Wicks S., Taylor C.M., Luo M., Blanchard E. 4th, Ribnicky D., Cefalu W.T., Mynatt R.L. & Welsh D.A. (2014). Artemisia supplementation differentially affects the mucosal and luminal ileal microbiota of diet-induced obese mice.  Nutrition, 30(7), S26-30. PMID: 24985102.
  7. Luo, M., Brown, R. L., Chen, Z.Y., Menkir, A., Jiujiang Yu, J.J., Bhatnagar, D. 2011. Transcriptional profiles uncover Aspergillus flavus induced resistance in mature maize kernels. Toxins 3(7): 766-785.
  8. Chang, P.K., Scharfenstein, L.L., Luo, M., Mahoney, N., Molyneux, R.J., Yu, J.J., Campbell, B.C. 2011. Loss of msnA, a putative stress regulatory gene, in Aspergillus parasiticus and Aspergillus flavus increased production of conidia, aflatoxins and kojic acid. Toxins 3 (1): 82-104.
  9. Luo, M., Liu, J., Lee, R. D., Scully, B. T., Guo, B.Z. 2010. Monitoring the expression of maize genes in developing kernels under drought stress using oligo-microarray. Journal of Integrative Plant Biology 52 (12): 1059–1074.
  10. Brown, R. L., Chen, Z.Y., Warburton, M., Luo, M., Menkir, A., Fakhoury, A., Bhatnagar, D. 2010. Discovery and Characterization of Proteins Associated with Aflatoxin-Resistance: Evaluating Their Potential as Breeding Markers. Toxins 2(4): 919–933.