As a basic science department in a medical school, researchers undertake both basic and translational approaches. Our investigators have substantial support from the National Institutes of Health, other federal agencies, the State of Louisiana and from industry. Details of our individual research projects, funding and publications can be found under the individual investigator links.

Immunology/Infectious Diseases/Cancer

The immunology research laboratories are predominantly focused on immunity and infection. There is a strong interest in the host response to sexually transmitted infections, including Chlamydia trachomatis, Human Immunodeficiency Virus (HIV), Human Papilloma Virus (HPV) and Simian Immunodeficiency Virus (SIV). The cellular immune response to Candida albicans, Toxoplasma gondii and Pneumocystis carinii are also under study.  Additional studies focus on T cell dysfunction in patients with cancer and tuberculosis, and the development of novel antibody-based therapies, diagnostics and vaccine strategies.

 Pamela Kozlowski, PhD                                              Alison Quayle, PhD

 Alistair Ramsay, PhD                                                  Guoshun Wang, DVM, PhD

 Arnold Zea, PhD                                                          Paul L. Fidel, Jr., PhD (Joint Faculty)

Krzysztof Reiss, PhD (Joint Faculty)
 

Bacterial Pathogenesis

One major area of interest is the pathogenesis and the chemotherapy of eye infections. Other interests include: the study of the seaborne pathogen Vibrio vulnificus, and microbial ecology and population ecology.

Ashok Aiyar, PhD                                                         Jeffery A. Hobden, PhD

Li Shen, MD, PhD                                                         Christopher Taylor, PhD

Zezhang (Tom) Wen, PhD (Joint Faculty)      


Eukaryotic Pathogens

The molecular mycology and parasitology laboratories use molecular genetics, immunochemistry, biochemical techniques, animal models and molecular immunology to study the opportunistic fungal pathogens Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus as well as the protozoan parasites Trypanosoma cruzi, Leishmania major, and Leishmania mexicana.

Doug Johnston, PhD                                                  Ben Kelly, PhD

Joy Sturtevant, PhD                                                   Hong Xin, MD, PhD

Ping Wang, PhD                                                         Mairi Noverr, PhD (Joint Faculty)


Molecular Virology and Viral Pathogenesis

The molecular virology laboratories investigate several aspects of viral pathogenesis including mother-to-infant transmission of HIV and SIV, latency of Epstein-Barr virus, and Herpesvirus infections.  Studies also focus on mechanisms of viral entry, the development of anti-virals, vaccines, and techniques for viral detection.

Angela Martin Amedee, PhD                                        Jennifer Cameron, PhD

Timothy Foster, PhD                                                    Michael Hagensee, MD, PhD (Joint Faculty)

Francesca Peruzzi, PhD (Joint Faculty)