Ping Wang, PhD

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	Ping Wang, PhD Associate Professor of Pediatrics and Microbiology Division of Research The Research Institute for Children 200 Henry Clay Avenue New Orleans, LA 70118 Phone: (504) 568-2578 Fax: (504) 896-5379 pwang@chnola-research.org Research Institute for Children at Children's Hospital Faculty Website at Research Institute for Children
Degrees	BS - 1982 Nanjing Agricultural University, PRC MS - 1985 Nanjing Agricultural University, PRC PhD - 1991 Cornell Univervsity, Ithaca, NY
Bio	Recent progresses in genetic manipulation and sequencing projects have made the human fungal pathogen Cryptococcus neoformans an ideal model for studying mechanisms of fungal pathogenesis. Our research efforts are to explore the roles of G-protein mediated signal transduction in fungal pathogenesis utilizing both genetic and biochemical approaches.
Research Interests	Pathogenic fungi Signal transduction
Selected Publications	Shen, G, Wang, YL, Whittington, A, Li, L, and Wang, P, The RGS protein Crg2 regulates pheromone and cAMP signaling in Cryptococcus neoformans. Eukaryotic Cell 7:1540-48, 2008. Lie, L, Shen, G, Zhang, ZG, Wang, YL, Thompson, JK, and Wang, P, Canonical heterotrimeric G-proteins regulating mating and virulence of Cryptococcus neoformans. Mol. Biol. Cell 18: 4201-09, 2007. Palmer, D, King, J, Li, L, Prat, A, and Wang, P, Gib2, a novel Gbeta-like/RACK1 homolog function as a Gbeta subunit in cAMP signaling and is essential in Cryptococcus neoformans. J. Biol. Chem. 281: 32596-605, 2006. Wang P, Nichols CS, Lengeler KB, Cardenas ME, Cox GM, Perfect JR, Heitman J, Mating type specific and nonspecific PAK kinase homologs play shared and divergent roles in cytokinesis, differentiation and virulence of Cryptococcus neoformans, Eukaryotic Cell 1: 257-272, 2002. Wang P, Cardenas ME, Cox GM, Perfect JR, Heitman J, Two cyclophilin A homologs with shared and distinct functions important for growth and virulence of Cryptococcus neoformans, EMBO Report 2: 511-518, 2001. Wang P, Perfect JR, Heitman J, The heterotrimeric G protein beta subunit GPB1 is required for mating and haploid fruiting in Cryptococcus neoformans, Mol Cell Biol 20: 352-362, 2000. Wang P, Sandrock BW, VanEtten HD, Disruption of the cyanide hydratase gene in Gloeocercospora sorghi increases its sensitivity to phytoanticipin cyanide but does not affect its pathogenicity on cyanogenic plant sorghum, Fungal Gen Biol 28: 126-134, 1999. Wang P, Larson TG, Chen CH, Pawlyk DM, Clark JA, Nuss DL, Cloning and characterization of a general amino acid control transcriptional activator from the chestnut blight fungus Cryphonectria parasitica, Fungal Gen Biol 23: 81-94, 1998. Wang P, Nuss DL, Induction of a Cryphonectria parasitica cellobiohydrolase I gene is suppressed by hypovirus infection and regulated by a GTP-binding-protein-linked signaling pathway involved in fungal pathogenesis, Proc Natl Acad Sci USA 92: 11529-11533, 1995.

Associate Professor of Pediatrics and Microbiology Division of Research

Associate Professor of Pediatrics and Microbiology
Division of Research