
| Administration | Basic Sciences | Clinical Sciences | Centers of Excellence |
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| Degrees |
PhD - 1970 |
| Bio |
Current research interest in the Thompson lab focuses on the role of local immune and inflammatory responses to infections, especially oral Candida albicans infections in HIV-infected individuals, in collaboration with Dr. Fidel. In addition, methods are being developed and validated to allow measurement of local microbial load, specifically with HIV and Candida albicans, in tissue biopsy and other materials obtained from these infected patients. This information will be contrasted to other data being collected on systemic responses in those same patients. Finally, in other research, the role of a human intracisternal A-type retrovirus in autoimmune disease is being examined, especially in relationship to the effects of viral infection on cellular apoptosis, in collaboration with Dr. Gallaher. |
| Research Interests |
Immune responses Viruses Autoimmunity |
| Selected Publications |
Leigh, J E., Barousse, M, Swoboda, R, Myers, T, Hager, S, Wolf, N, Cutright, J, Thompson, JJ, Sobel, JD, and Fidel, PL, Jr., Candida-specific systemic cell-mediated immune reactivities, J. Infect. Dis. 183:277-285, 2001. Deas, JE, Thompson, JJ, Fermin, CD, Liu, LL, Martin, D, Garry, RF, Gallaher, WR, Viral induction, transmission and apoptosis among cells infected by a Human Intracisternal A-type retrovirus, Virus Res. 61:19-27, 1999. JE Deas, LG Liu, JJ Thompson, DM Sander, SS Soble, RF Garry, and WR Gallaher, Reactivity of sera from systemic lupus erythematosus and Sjogren's Syndrome with peptides derived from HIV p24 capsid antigen, Clin. Diagnos. Lab. Immunol. 5:181, 1998. Lee, LT and Thompson, JJ, Identification of cryptic peanut agglutinin-reactive sites in human lipoprotein(a), Biochem. Biophys. Acta 1302:79, 1996. |
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