Chuan-dong Geng Ph.D.
Research Assistant Professor
Geng CD, Vedeckis WV.A New, Lineage Specific, Autoup-Regulation Mechanism for Human Glucocorticoid Receptor Gene Expression in 697 Pre-B-Acute Lymphoblastic Leukemia Cells.Mol Endocrinol. 2010 Nov 17. [Epub ahead of print]
Geng CD, Vedeckis WV. Use of Recombinant Cell-Permeable Small Peptides To Modulate Glucocorticoid Sensitivity of Acute Lymphoblastic Leukemia Cells.Biochemistry. Oct 19;49(41):8892-901; (2010) Open PDF of this articl
Geng CD, Schwartz JR, Vedeckis WV. A Conserved Molecular Mechanism Is Responsible For The Auto-Upregulation Of Glucocorticoid Receptor Gene Promoters. Mol Endocrinol. Oct 22; (2008)
Geng, C.-D. and Vedeckis W.V. C-Myb and members of the c-Ets family of transcription factors act as molecular switches to mediate opposite steroid regulation of the human glucocorticoid receptor 1A promoter. J. Biol. Chem. 280: 43264-43271 (2005)
Geng, C.-D., Pedersen, K.B., Nunez, B.S. and Vedeckis, W.V. Human glucocorticoid receptor alpha transcript splice variants with exon 2 deletions: evidence for tissue- and cell type-specific functions. Biochemistry, 44: 7395-405 (2005)
Nunez, B.S., Geng, C.-D., Pedersen, K.B., Millro-Macklin, C.D. and Vedeckis, W.V. Interaction between the interferon signaling pathway and the human glucocorticoid receptor gene 1A promoter. Endocrinology, 146: 1449-1457 (2005)
Garg, R., Geng, C.-D., Miller, J.L., Callens, S., Tang, X., Appel, B. and Xu, B. Molecular cloning and characterization of the catalytic domain of zebrafish homologue of the ataxia-telangiectasia mutated gene. Mol. Cancer Res., 2: 348-353 (2004)
Pedersen, K.B., Geng, C.-D. and Vedeckis, W.V. Three mechanisms are involved in glucocorticoid receptor autoregulation in a human T-lymphoblast cell line. Biochemistry, 43:10851-10858 (2004)
Breslin MB, Geng, C.-D. Vedeckis WV. Multiple promoters exist in the human GR gene, one of which is activated by glucocorticoids. Mol Endocrinol.Aug;15(8):1381-95 (2001)
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