Congratulations to Aliyah Pierre from Dr. Rinku Majumder's Lab who won 3rd place in the annual research competition by REU National Science Foundation.
New Link Between Hypoxia and Thrombosis
A team of researchers from the department of Biochemistry, LSU Health Science Center, New Orleans, School of Medicine and University of Massachusetts Medical School, led by Rinku Majumder, PhD, Associate Professor of Biochemistry at LSUHSC just published an article in the prestigious journal "Blood"( https://doi.org/10.1182/blood-2018-04-841585).
This group has shown by biochemical and genetic approaches that decrease in concentration of a body's natural anticoagulant, Protein S, is responsible for increased thrombotic risk at low oxygen condition (hypoxia). The journal editorial board has come out with a commentary on this topic (https://doi.org/10.1182/blood-2018-06-854976) and observed-"This is an important contribution to our understanding of the molecular basis of the augmentation of thrombosis by hypoxia." Hypoxia is common in many disease states, including cancer. However, hypoxia mediated potentiation of thrombotic episode due to down regulation of a body's natural anticoagulant, protein S is novel. This article is also selected as one of the featured articles on the cover page of the issue.
Other members of the research team include Dr. Vijaya S. Pilli, Mr. Arani Datta and Dr. Sadaf Afreen from LSUHSC and Ms. Donna Catalano and Dr. Gyongyi Szabo of Umass Medical Center.
Research led by Suresh Alahari, PhD, Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has shown for the first time that a tiny piece of RNA deregulates energy metabolism, an emerging hallmark of cancer. The finding identifies a new target for therapeutic intervention in breast cancer. The research is published in Molecular Cancer.
Sunyoung Kim, founder of Chosen Diagnostics Inc, was selected by the State Department and Small Business Administration in Washington DC to be one of the 300 US delegates to the Global Entrepreneurship Summit (GES) in Hyderabad India. A LSU Health spin-out company, Chosen Diagnostics provides diagnostic tests that can personalize and improve infant health. GES serves as a link between governments and the private sector and champions new opportunities for investment. Over 1000 delegates from 150 countries attended the meeting in Hyderabad, India from November 28-30, 2017. Participants are picked for their ability to catalyze innovation, investment, and mentoring. The focus of this eighth annual summit was supporting women entrepreneurs, addressing some of the most intractable global challenges, and fostering economic growth globally. Ivanka Trump headlined the United States delegation and Indian Prime Minister Narendra Modi headed the delegation from the host country.
Congratulations to Dr. Joseph Chaney for his appointment as an Assistant Professor of Chemistry at Xavier University!
Alahari Lab in the News
Research led by Suresh Alahari, PhD, Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has demonstrated the potential of a protein to treat or prevent metabolic diseases including obesity and diabetes. The lab's findings have been published online in the Journal of Biological Chemistry; and, more recently, have been featured on Fox 8 News and other local news stateions.
Follow the link below to see the video from Fox 8 News:
Journal of Biological Chemistry
Dr. Alahari and his lab have been featured in the latest version of The Journal of Biological Chemistry for their groundbreaking research on obesity and diabetes. A number of other news sources have also recently published this article (see below). Congratulations to the entire Alahari Lab on this accomplishment!
LIFT2 Grant Award
The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College has established the "Leveraging Innovation for Technology Transfer" (LIFT2) Grant program to support the furtherance of innovation and commercialization through proof-of-concept research.
On May 3, 2017 Dr. Desai and her lab received a $50,000 LIFT2 award to continue their current research. This grant was awarded to help fund her research project titled: "ISGylation: a potential diagnostic/prognostic biomarker for neurodegenerative diseases." Congratulations to Dr. Desai and her lab on this accomplishment!
Biz The Magazine - May 2017
Dr. Sunyoung Kim and her startup company, Chosen Diagnostics, were featured on the cover of the May 2017 issue of Biz New Orleans The Magazine. In the article, Dr. Kim reflects on what it takes to build a healthcare startup and why Louisiana is the right place for it to take shape.
In November, Chosen Diagnostics won the $25,000 grand prize at the 2016 BioChallenge Startup Competition, an annual event organized by the New Orleans BioInnovation Center to identify and support local life sciences startups. She is the first woman to win the award.
On the heels of that success, the company took top honors in the 2017 JEDCO Challenge, held this past March during New Orleans Entrepreneur Week. The win included a $60,000 prize package. Judging panels weren’t the only ones who recognized the company’s merit — in both competitions, Chosen Diagnostics won the “crowd favorite” prizes as well.
NPR Out to Lunch
Dr. Sunyoung Kim was a featured guest on NPR's "Out to Lunch" program on March 2, 2017. During the interview, Dr. Kim discussed a new test her lab is working on that will help diagnose Necrotizing Entercolitis (NEC) in newborn babies. NEC is a condition primarily seen in premature infants and is the second most common cause of morbidity for the vulnerable population. Current tests are only about 40% accurate and only work after clinical symptoms develop. An NEC diagnosis can easily overwhelm parents who may already be having a hard time with the unexpected early arrival of their child. Developing a test that allows for detection of NEC before symptoms develop is a huge leap forward for Neonatologists. Early diagnosis and intervention will improve outcomes for the affected infants.
You can listen to Dr. Kim's interview in full by clicking on the following link:
Most Cited Journal Article: Molecular Cancer
Congratulations to Dr. Alahari and his lab team on publishing the most cited article of 2016 from the open access journal, Molecular Cancer. This is a great honor for Dr. Alahari, as Molecular Cancer is one of the most prestigious scientific journals, with a 5.9 impact rating.
A link to the article can be found here:
Silvia Juliana Serrano-Gomez, Mazvita Maziveyi, and Suresh Alahari
Prestigious NSF I-Corps Award
Congratulation Dr. Sunyoung Kim on this great news: https://www.eurekalert.org/pub_releases/2016-12/lsuh-tfe120116.php
NSF awarded LSU Health New Orleans a $50,000 grant so the LSU Health New Orleans reasearchers led by Dr. Kim can participate in the national NS Innoviation Corps (ICorps) Program in January 2017.