Dr. Chatterjee Wins Prestigious Award From
the American Association of Hematology at Their Annual Meeting
For the second consecutive year, Dr. Sabyasachi Chatterjee, post-doctoral researcher in the laboratory of Dr. Rinku Mjaumder, Associate Professor of Biochemistry and Molecular Biology, has been received the Abstract Achievement Award from the American Society of Hematology at their annual meeting. His abstract titled “Laminin G domains of Protein S bind and inhibit FIXa” was co-authored with Amber Sylvain, Satish Pilli, Whitney Fant, Doerte Fricke, Terry Watt and Rinku Majumder and appeared in the November 13th edition of Blood. Previous work shows Protein S binds to the FIXa protein to down regulate coagulation in the clotting response. Deficiencies in Protein S are associated with deep vein thrombosis, myocardial infarction, ischemic stroke, and vascular calcification. Dr. Chatterjee and his colleagues used a selection of biochemical and biophysical methods to map the binding between Protein S and FIXa for the first time, an important step in directing future drug design to regulate this interaction and rates of blood clotting.