Translational Genomics Core (TGC)
The LSUHSC, Stanley S. Scott Cancer Center's Translational Genomics Core (TGC) TGC is committed to our research community through service, training, teaching and organizing seminars to keep our community informed of recent development in specific topics concerning genomics.
To fulfill this goal, we follow these Specific Aims: 1- To provide expert training in the different genomic techniques used in the TGC to any interested researcher. Our policy is to help people understand the technologies in the TGC for a better use of them and to obtain the best results possible. To do this we invite researchers from time to time to come and work with us in the processing of their own samples. In this way they could better understand the procedures used in the TGC and would improve the way to handle their samples, improving the chances of better results. 2- To provide a high quality service to our genomic users. In order to accomplish this we are always learning about the techniques used in the TGC and keep a close contact with our providers to look for new improvements, way to reduce cost, implementation of new techniques and troubleshooting. 3- To keep our equipment up-to-date in terms of service and software update to better serve our users. To accomplish this, the Stanley S. Scott Cancer Center has been instrumental in the establishment of service contracts with Illumina and Life Technologies (now Thermo Scientific), vendors of our three major instruments. These contracts are renewed annually and include visits to our Core for preventive maintenance of the equipment. In addition, both companies have remote assistance and the “Share Desktop” option, so that specialized technicians can access our equipment remotely for diagnostics, software upgrades and assistance. 4- To help in the generation of preliminary data for our scientific community. The TGC has been instrumental in helping our New Orleans scientific community generate high quality data to be included as preliminary information in grant proposals as well providing letters of support to researchers submitting grant proposals.
Core Director:
Jovanny Zabaleta, PhD
Phone: 504-210 2979
Email: jzabal@lsuhsc.edu
The Facility is committed to providing quality service by fulfilling the needs of the research community in a consistently rapid, dependable, and economical fashion. Services include automated DNA sequencing, using state-of-the-art instrumentation and the latest protocols to ensure high quality results at reasonable prices. The Facility houses an Illumina NextSeq500, a MiSeq (both for next generation sequencing), and an Illumina iScan for the analysis of microarray-based analyses including methylation, GWAS, microarray-based exome analysis, and several focused arrays, among others. The Core also has a 7900HT and QuantStudio 12K real-time PCR systems from ThermoScientific for gene expression validation, a Covaris DNA fragmentation instrument for the preparation of DNA for exome sequencing, a ddSingle cell isolator from Biorad, a 3'-based sequencing technology for the analysis of mRNA levels in single cell suspensions.