2016 12:40:17 PM

Jeff Gidday, PhD

Professor of Ophthalmology, Neuroscience, and Physiology

Clinical Sciences Research Building, Room 454
533 Bolivar St.
New Orleans, LA 70112

(O): 504.568.2360 





BS, Biological Sciences
University of Michigan, Ann Arbor

PhD, Physiology
University of Virginia, Charlottesville

Clinical Interests


retinal disease

retinal neurodegeneration



vascular dementia

traumatic brain injury

Research Interests

endogenous neuroprotection for glaucoma and other CNS axonopathies

adaptive epigenetics

transgenerational epigenetics

CNS neurovascular protection


ischemic and other retinopathies


vascular cognitive impairment

neonatal brain injury



Selected Publications

Gidday, J.M.  Cerebral preconditioning and ischemic tolerance.  Nat. Neurosci. Rev. 7: 437-448, 2006.

Zhu, Y., Y. Zhang, B.A. Ojwang, M.A. Brantley Jr., J.M. Gidday.  Long-term tolerance to retinal ischemia by repetitive hypoxic preconditioning:  Role of HIF-1α and heme oxygenase-1. Invest. Ophthalmol. Vis. Sci. 48: 1735-1743, 2007.

Zhu, Y., L. Zhang, J.M. Gidday.  Deferroxamine preconditioning promotes long-lasting retinal ischemic tolerance.  J. Ocular Pharmacol. Therap. 24: 527-535, 2008.

Gidday, J.M.  Pharmacologic preconditioning:  Translating the promise.  Transl. Stroke Res. 1: 19-30, 2010.

Stowe, A.M., T. Altay, A.B. Freie, J.M Gidday.  Repetitive hypoxia extends endogenous neurovascular protection for stroke.  Ann. Neurol. 69:975-985, 2011.

Wacker, B.K., A.B. Freie, J.L. Perfater, J.M. Gidday.  Junctional protein regulation by sphingosine kinase 2 contributes to blood-brain barrier protection in hypoxic preconditioning-induced ischemic tolerance.   J. Cereb. Blood Flow Metab. 32: 1014-1023, 2012.

Stowe, A.M., B.K. Wacker, P.D. Cravens, J.L. Perfater, M.K. Li, R. Hu, A.B. Freie, O. Stuve, J.M. Gidday.  CCL2 upregulation triggers hypoxic preconditioning-induced protection from stroke.  J. Neuroinflammation 9: 33, 2012.

Zhu, Y., L. Zhang, J.F. Schmidt, J.M. Gidday.  Glaucoma-induced injury of retinal ganglion cell soma and axons prevented by hypoxic preconditioning:  A model of ‘glaucoma tolerance’.  Mol. Medicine 18: 697-706, 2012.

Wacker, B.K., J.L. Perfater, J.M. Gidday.  Hypoxic preconditioning induces stroke tolerance in mice via a cascading HIF, sphingosine kinase, and CCL2 signaling pathway.  J. Neurochem. 123: 954-962, 2012.

Zhu, Y., Y. Sasaki, L. Zhang, J. Milbrandt, J.M. Gidday.  Protection of mouse retinal ganglion cell axons and soma from glaucomatous and ischemic injury by cytoplasmic overexpression of Nmnat1.  Invest. Ophthalmol. Vis. Sci. 54: 25-36, 2013.

McLaughlin, BA and J.M. Gidday.  Poised for success:  Implementation of sound conditioning strategies to promote endogenous protective responses to stroke in patients.  Transl. Stroke Res. 4: 104-113, 2013.

Zhu, Y., L. Zhang, J.M. Gidday.  Role of HIF-1α in preconditioning-induced protection of retinal ganglion cells in glaucoma.  Mol. Vis. 19: 2360-2373, 2013.

Gidday, J.M., L. Zhang, Y. Zhu.  Enhanced retinal ganglion cell survival in glaucoma by hypoxic postconditioning after disease onset.  NeuroTherapeutics 12:502-514, 2015.

Gidday, J.M.  Extending injury- and disease-resistant CNS phenotypes by repetitive epigenetic conditioning.   Front. Neurol. 6:42, 2015.

Gidday, J.M.  Cerebrovascular ischemic protection by pre- and post-conditioning.  Brain Circulation 1: 97-103, 2015.


Center of Excellence