Jayne S. Weiss, M.D.

Associate Dean of Clinical Affairs
Chief Medical Officer, LSU Healthcare Network
Chair, Department of Ophthalmology
Professor of Ophthalmology, Pathology, and Pharmacology
Herbert E. Kaufman M.D. Endowed Chair in Ophthalmology
Director, LSU Eye Center of Excellence


Academic Office:

LSU Eye Center at LSU Health Sciences Center, New Orleans
533 Bolivar Street/CSRB 459
New Orleans, LA 70112
Phone: 504-568-3156
Fax: 504-568-2385

Clinical Offices:

LSU Eye Clinic at LSU HealthCare Network, New Orleans
3700 St. Charles Avenue, 6th Floor
New Orleans, LA 70115
Phone: 504-412-1200
Fax: 504-899-2866
(To schedule an appointment for this clinic only, you may use the link below.)

Request an Appointment

LSU Eye Clinic at University Medical Center, New Orleans
2000 Canal Street, Clinic Building, 3rd floor
New Orleans, LA 70112
Ophthalmology Clinic: 504-702-3950
Referral fax line: 504-702-2051
Clinic fax line: 504-702-4425

LSU Eye Clinic at Our Lady of the Angels Hospital, Bogalusa
433 Plaza Street, 2nd floor
Bogalusa, LA 70427
Phone: 985-730-7209
Fax: 985-730-7195

LSU Eye Clinic at Our Lady of the Lake Regional Medical Center, Baton Rouge
9032 Perkins Road
Baton Rouge, LA 70810
Phone: 225-768-5842
Fax: 225-354-2075

LSU Eye Clinic at University Hospitals and Clinics, Lafayette
401 St. Julien Avenue
Lafayette, LA 70506
Phone: 337-262-2500
Fax: 337-262-2506


BA (Biology) summa cum laude
State University of New York at Buffalo

MD Alpha Omega Alpha Honor Society
Mt. Sinai School of Medicine, New York, NY


Internship in Internal Medicine
Beth Israel Medical Center, New York, NY

Residency in Ophthalmology
Bascom Palmer Eye Institute University of Miami, Miami, FL

Fellowship in Ocular Pathology
Massachusetts Eye & Ear Infirmary, Harvard, Boston, MA

Fellowship in Cornea and External Diseases
Emory University. Atlanta, GA

Clinical Interests

LASIK in patients with other ocular or systemic diseases
Complications of refractive surgery
Cataract surgery
Corneal surgery
Corneal dystrophies

Research Interests

Genetic mapping and pathophysiology of corneal dystrophies, particularly Schnyder corneal dystrophy

Selected Publications

Lisch W, Weiss JS. Early and late clinical landmarks of corneal dystrophies. Exp Eye Res. 2020 Jul 26:108139. doi: 10.1016/j.exer.2020.108139. Online ahead of print.PMID: 32726603

Soh YQ, Kocaba V, Weiss JS, Jurkunas UV, Kinoshita S, Aldave AJ, Mehta JS. Corneal Dystrophies Nat Rev Dis Primers. 2020 Jun 11;6(1):46. doi: 10.1038/s41572-020-0178-9.PMID: 32528047

Giannaccare G, Bolognesi F, Biglioli F, Marchetti C, Mariani S, Weiss JS, Allevi F, Cazzola FE, Ponzin D, Lozza A, Bovone C, Scorcia V, Busin M, Campos EC.  In Vivo and Ex Vivo Comprehensive Evaluation of Corneal Reinnervation in Eyes Neurotized With Contralateral Supratrochlear and Supraorbital Nerves. Cornea. 2020 Feb;39(2):210-214. doi: 10.1097/ICO.0000000000002083.

Lisch W, Weiss JS. Clinical and genetic update of corneal dystrophies. Exp Eye Res. 2019 Sep;186:107715. doi: 10.1016/j.exer.2019.107715. Epub 2019 Jul 10. Review. Erratum in: Exp Eye Res. 2020 Jan 24;:107929.

Weiss JS, Moller HU, Lisch W. The Corneal Dystrophies-Does the Literature Clarify or Confuse? American Journal of Ophthalmology. 2018 Sept 11. doi: 10.1016/j.ajo.2018.07.047.

Dong F, Jin X, Boettler MA, Sciulli H, Ab-Asab M, Del Greco C, Wang S, Hu YC, Campos MM, Jackson SN, Muller L, Woods S, Combs CA, Zhang J, Nickerson ML, Kruth HS, Weiss JS, Kao WW. A Mouse Model of Schnyder Corneal Dystrophy with the N100S Point Mutation. Nature Scientific Reports; 2018 8 July:8:2019.  doi: 10.1038/s41598-018028545-0.

Giannaccare G, Weiss JS, Sapigni L, Bovone C, Mattiolig L, Campos EC, Busin M. Immunologic Stromal Rejection After Deep Anterior Lamellar Keratoplasty With Grafts of A Larger Size (9mm) for Various Stromal Diseases Cornea. 2018 Mar 14. doi: 10.1097/ICO.0000000000001584.

Kitazawa K, Wakimasu K, Kayukawa K, Sugimoto M, Nakai  Weiss JS, Ueno M, Sotozono C, Kinoshita S. Long-term Outcome Post Penetrating Keratoplasty in a Pedigree with the G177E Mutation in the UBIAD1 Gene for Schnyder Corneal Dystrophy. Cornea. 2018 May;37(5):554-559. doi: 10.1097/ICO.0000000000001511.

Lisch W, Wasielica-Poslednik J, Kivela T, Schlotzer-Screhardt U, Rohrach JM, Sekundo W, Pleye U, Lisch C, Desuki A, Rossmann H, Weiss JS. The Hematological Definition of Monoclonal Gammopathy of Undetermined Significance in Relation to Paraproteinemic Keratopathy (An American Ophthalmological Society Thesis). The Transaction of the American Ophthalmology Society Aug;114:T7 2016

Weiss JS. UVA protection from Auto Glass, Cataracts and the Ophthalmologist.JAMA Ophthalmol 134:776-777; 2016

Seitz B, Lisch W, Weiss J. Die revidierte neuseste IC3D-Klassifikation der Hornhautdystrophien. Klin Monatsbl. Augenheilkd 232:283-294; 2015

Levitt AE, Galor A, Weiss JS, Felix ER, Martin ER, Patin DJ, Sarantopoulous KD, Levitt RC. Chronic dry eye symptoms after LASIK:parallels and lessons to be learned from other persistent post-operative pain disorders. Molecular Pain.;11(1):21. doi: 10.1186/s12990-015-0020-7.epub April 21, 2015

Weiss JS, Møller HU, Aldave AJ, Seitz B, Bredrup C, Kivelä T, Munier FL, Rapuano CJ, Nischal KK, Kim EK, Sutphin J, Busin M, Labbé A, Kenyon KR, Kinoshita S, Lisch W. The IC3D Classification of Corneal Dystrophies-Edition 2. Cornea epub  Jan 13, 2015

Fredericks, W; McGarvey, T; Wang, H; Zheng, Y; Fredericks, N; Yin, H; Wang, L; Hsiao, W; Lee, R; Weiss, J; Nickerson, M; Kruth, H; Rauscher III, F; Malkowicz, B. The TERE1 (UBIAD1) bladder tumor suppressor protein interacts with mitochondrial TBL2: regulation of trans-membrane potential, oxidative stress and SXR signaling to the nucleus. Journal of Cellular Biochemistry  epub Apr 8, 2013

Nickerson ML,  Bosley AD, Weiss JS, Kostiha BN, Hirota Y,  Brandt W, Esposito D, Kinoshita S,  Wessjohann L, Morham S, Andresson T,  Kruth HS, Okano T, Dean M. The UBIAD1 Prenyltransferase Links Menaquione-4 Synthesis to Cholesterol Metabolic Enzymes.  Human Mutation, epub Nov 27 2012

Lisch W, Bron AJ, Munier FL, Schorderet DF, Tiab L, Lange C, Saikia P, Reinhard T, Weiss JS, Gundlach E, Pleyer U, Lisch C, Auw-Haedrich C. Francescetti Hereditary Recurrent Corneal Erosion. American Journal of Ophthalmology epub Nov 20, 2012.

Lisch W, Bron AJ, Munier FL, Schorderet DF, Tiab L, Lange C, Saikia P, Reinhard T, Weiss JS, Gundlach E, Pleyer U, Lisch C, Auw-Haedrich C. Francescetti Hereditary Recurrent Corneal Erosion. American Journal of Ophthalmology  153: 1073-1081, 2012 Jun

Weiss JS, Lisch W, Kinoshita S, Aldave AA, Belin MW, Kivela T, Busin M, Munier FL, Seitz B, Sutphin J, Bredrup C, Mannis MJ, Rapuano C: Hornhautdystrophien. Klinische Monatsblatter fur Augenheilkunde 228 (supplement) 1-40, 2011.

Fredericks W, McGarvey T, Wang H, Puthiyaveettil R, Tomaszewski J, Sepulveda J, Labelle E, Weiss J, Nickerson M, Kruth H, Brandt W, Wessjohann L, Malkowicz B: The bladder tumor suppressor protein TERE1 (UBIAD1) modulates cell cholesterol: implications for tumor progression. DNA Cell  Biology July 8, 2011.

Weiss JS, Khemichian AJ: Differential diagnosis of Schnyder corneal 56 dystrophy.  Developmental Ophthalmology 48:-epub April 26, 2011.

Moller H, Weiss JS: The IC3D Corneal Dystrophy Classification System. Developments in Ophthalmology epub April 26, 2011. 

Weiss JS, Wiaux C, Vivak Y, Raber I, Eagle R, Mequio M, Aldave A: Reported p.Asp240Asn mutation in UBIAD1 suggests central discoid corneal dystrophy is a variant of Schnyder corneal dystrophy. Cornea 29:777-780, 2010.

Weiss JS and the Fifth ARVO-Pfizer Ophthalmics Research Institute Working Group:  Corneal dystrophies: Molecular genetics to therapeutic intervention. Fifth Annual ARVO/Pfizer Ophthalmics Research Institute.  Investigative Ophthalmology and Visual Sciences 51:5391-5402, 2010.

Nickerson ML, Kostiha BM, Brandt W, Fredericks W, Xu KP, Yu FS, Gold B, Chodosh J, Goldberg M, Lu DW, Yamada M, Tervo TM, Grutzmacher D, Croasdale C, Hoeltzenbein M, Sutphin J, Malkowicz B, Wessjohann L, Kruth  HS,  Dean M, Weiss JS: Schnyder UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy. PLoS ONE 5:e10760, 2010.

Moller H, Kestelyn P, Weiss JS: Pediatric corneal dystrophies. A plea for pictures (Letter to the Editor). Cornea 29:1469, 2010.

Weiss JS: Corneal dystrophy classification.  (Letter to the Editor). Ophthalmology 116:1013-1014, 2009.

Weiss JS: Molecular genetics and the corneal dystrophies--What is next (Editorial). American Journal of Ophthalmology 148:477-478, 2009.

Weiss JS: Schnyder corneal dystrophy. Current Opinion in Ophthalmology  20:292-298, 2009.

Weiss JS. More on Schnyder dystrophy (Letter to the Editor).  Ophthalmology 116:2260, 2009.

Weiss JS, Kruth HS, Kuivaniemi H, Tromp G, Karkera J, Mahurkar S, Lisch W, Dupps Jr W, White P, Winters R, Kim C, Rapuano C, Sutphin J, Reidy J, Hu FR, Lu DW, Ebenezer N, Nickerson M: Rapid Communication--Genetic analysis of 14 families with Schnyder crystalline corneal dystrophy reveals clues to UBIAD1 protein function. American Journal of Medical Genetics 146:271-283, 2008.

Weiss JS, Mokhtarzadeh M: Myopic regression after LASIK: A medical alternative to surgical enhancement (Editorial). American Journal of Ophthalmology 145:189-190, 2008.

Weiss JS, Møller H,  Lisch W, Kinoshita S,  Aldave AA,  Belin MW,  Kivela T,  Busin M,  Munier FL, Seitz B,  Sutphin J, Bredrup C, Mannis MJ,  Rapuano C, Van Rij G, Kim EK, Klintworth GK: The IC3D classification of corneal dystrophies. Cornea 27(supplement 2):1-42, 2008.

Additional Info

Board Certifcation:

American Board of Ophthalmology

Selected Special Activities:

Former Chair, FDA Panel on Ophthalmic Devices
Editorial Board, Cornea Journal
Editorial Board, American Journal of Ophthalmology
Former Member, National Advisory Eye Council, NEI
Former Chair, American Academy of Ophthalmology Basic and Clinical Sciences Course
Former Science Program Director, Eye Bank of America


2020 Cornea Society Castroviejo Award Recipient
Advisory Committee Service Award from the US Food & Drug Administration
Secretariat Award and Honor Award, American Academy of Ophthalmology
Knight of Sight award, Louisiana Lions Eye Foundation
Best Doctors in America, Who's Who
Alpha Omega Alpha Medical Honor Society
Fulbright Association Lifetime Member
Best Doctors in New Orleans and Louisiana


American Academy of Ophthalmology
Castroviejo Corneal Society
Fulbright Association Lifetime Member
Alpha Omega Alpha
Bascom Palmer Eye Institute Alumni Association
Association of Heed Fellows
American Ophthalmology Society
Association of University Professors in Ophthalmology
New Orleans Academy of Ophthalmology
New England Ophthalmology Society
Louisiana Academy of Eye Physicians and Surgeons