School of Medicine

Neuroscience Center of Excellence


Study Reports Potential Target and Compounds to Slow the Development of Alzheimer's Disease

Study Reports Potential Target and Compounds to Slow the Development of Alzheimer's Disease article about the Neuroscience Center

La. as neurosciences center would boost economy

LSU Health Contributes to Research Suggesting Late-Onset Retinal Degeneration Mechanism & Potential RX

The Distinguished Lecture Series Presents: “Uncovering rules of photoreceptors long life”
Nicolas G. Bazan, M.D., Ph.D.; Thursday, April 1st, 2021: 4:00PM - 5:00PM

Unraveling Neurodegenerative Diseases with Jess

Could diet ward off some brain diseases?

Bazan One of Few Appointed Foreign Adjunct Professor at Prestigious Karolinska Institutet

LSU Health New Orleans Discovers Drug Development Target for Retinal Dystrophies

Dr. Nicolas Bazan - WWLTV Can music re-stimulate activity to the brain? Nov 10,2020


New Orleans, LA - Khanh Do, PhD, a postdoctoral fellow at LSU Health New Orleans Neuroscience Center of Excellence, is a member of the first group chosen by the National Institutes of Health (NIH) as NIH Outstanding Scholars in Neuroscience....Link

Eureka Alert


Study finds novel mechanism that may confer protection . .."I began developing my interests in neuroprotection and ophthalmology working under NicolasBazan, who mentored, motivated and guided me, as a medical school student from Denmark supported by a ...

Dr Nicolas Bazan - News, Articles, Whitepapers - Drug Target Jul 07, 2020 · News stories, articles and whitepapers referencing Dr Nicolas Bazan on Drug Target Review Recommended [LIVE WEBINAR] register now 10 September 15:00 BST on mobile phase optimisation for oligonucleotide analytical methods by LC-MS

Study finds novel mechanism that may confer protection ... 17, 2020 · "I began developing my interests in neuroprotection and ophthalmology working under Nicolas Bazan, who mentored, motivated and guided me, as a medical school student from Denmark supported by a ...

Novel mechanism may confer protection against day ago · “I began developing my interests in neuroprotection and ophthalmology working under Nicolas Bazan, who mentored, motivated and guided me, as a medical school student from Denmark supported by a Fulbright Scholarship (1994-1996), and from 2000-2003,” says Dr. Kolko.” I was lucky to work with and be inspired by Dr. Nicolas Bazan

Key to dialogue between brain cells to protect against stroke
Dr. Nicolas G. Bazan and Dr. Ludmila Belayev

Date: August 6, 2020
Source: Louisiana State University Health Sciences Center
Summary: LSU Health New Orleans research has unlocked a key fundamental mechanism in the communication between brain cells when confronted with stroke and found DHA not only protected neuronal cells and promoted their survival, but also helped maintain their integrity and stability.

Dr. Haydee Bazan and Dr. He on the cover of IOVS, June 2019

Dr. Haydee Bazan was inducted into the Association for Research in Vision and Ophthalmology (ARVO) Fellows Class
of 2019 as a Gold Fellow in the spring  ARVO Gold Fellow, 2019

The Advocate recognizes Dr. Bazan in New Orleans Area Business Honors for his recent DZNE Award Lecture and for the discovery of elovanoids

Dr. Bazan featured in New Orleans City Business: People This Week: New hires, promotions, and awards 

Dr. Bazan receives DZNE Award Lecture in Bonn, Germany

LSU Health New Orleans Graduate Student's (Khanh Do) Research Recognized Internationally

Khanh Do, a doctoral student at LSU Health New Orleans School of Graduate Studies

New Rx for allergic contact dermatitis. Link to article.

Retinal Pigment Epithelium and Photoreceptor Preconditioning Protection Requires Docosanoid Signaling. Press page. 

Lipid Corner: lipid research division of the American Society of Biochemistry and Molecular Biology

Newly discovered elovanoids called a 'transformative new concept of biology'

Inflammatory transcription confronts homeostatic disruptions 

LSU research shows value of Fish Oil, featured in The Advocate

LSU researchers are seeking to end Alzheimer's disease and start a new neurobiotech industry in Louisiana

Dr. Bazan in Research Features magazine "Connections: the importance of mentoring and collaboration to research success" and "A Marvelous Mind"

WWLTV and LSU Neuroscience Center of Excellence: Breakthrough for epilepsy, seizures

Medical News Today: LSU Health New Orleans discovers retina protein that may help conquer blindness

WWLTV and Una Vida: A Fable for Music and The Mind
LSUHSC discovery shows promise for eye and brain disease

Dr. Bazan's lab shows promise for eye and brain neurodegenerations treatments

Dr. Bazan featured on Research to Prevent Blindness Facebook page

Hippocampal Neuro-Networks and Dendritic Spine Perturbations in Epileptogenesis
Are Attenuated by Neuroprotectin D1

LSU Health New Orleans: Novel compound switches off epilepsy development

LSU Health New Orleans research finds novel compound switches off epilepsy development

Marshall and NB ARVO 1 2014 2014 9:40:41 AM

Barry James Marshall, MD, Nobel Laureate in Physiology or Medicine, 2005
and  Nicolas G. Bazan  at the ARVO 2014 meeting in Orlando, Florida.


Dr. Chu Chen's discovery and recent paper regarding COX-2: Δ9-THC-Caused Synaptic and Memory Impairments Are Mediated through COX-2 Signaling
The Cell press has released the following news on this paper because of the importance of the discovery:

Science has reported the story in its website:

Painkillers May Curb Memory Loss From Medical Marijuana

 Preventing marijuana-induced memory problems with OTC painkillers

Preventing Marijuana-induced Memory Problems with Over-the-counter Painkillers

In Mice Anti-Inflammatories Ameliorate Medical Marijuana's Memory Mishaps

Painkillers May Ease Marijuana Side Effects

Medical Marijuana 'Holds Promise for Alzheimer's Treatment'

Marijuana Memory Loss Prevented with OTC Painkillers?

Painkillers May Ease Marijuana Side Effects

Taking an NSAID stops marijuana memory loss and learning problems

Preventing Marijuana-induced Memory Problems with Over-the-counter Painkillers

Medical Marijuana 'Holds Promise for Alzheimer's Treatment'

Preventing Marijuana-Induced Memory Problems With Over-The-Counter Painkillers

Painkillers May Ease Marijuana Side Effects

Preventing marijuana-induced memory problems with over-the-counter painkillers

Painkillers May Ease Marijuana Side Effects

Preventing marijuana-induced memory problems with over-the-counter painkillers

Preventing Marijuana-Induced Memory Problems with Over-the-Counter Painkillers

New Orleans Biodistrict Newsletter; featuring Dr. Nicolas G. Bazan on page 3

Learning and memory: How neurons activate PP1, Hou, H., et al. 2013. J. Cell Biol. doi:10.1083/jcb.201303035
A study in The Journal of Cell Biology describes how neurons activate the protein PP1, providing key insights into the biology of learning and memory.

PP1 is known to be a key regulator of synaptic plasticity, the phenomenon in which neurons remodel their synaptic connections in order to store and relay information—the foundation of learning and memory. But how PP1 is controlled has been unclear. Now, a team led by researchers from the LSU Health Science Center describes several mechanisms for PP1 regulation that close some major gaps in our understanding of its role in neuronal signaling.

Among the novel findings, the researchers describe how the neurotransmitter NMDA leads to activation of PP1. They show that, when NMDA activates neuronal synapses, it switches off an enzyme, Cdk5, that would otherwise inhibit PP1. This allows PP1 to activate itself and promote synaptic remodeling. In addition, the researchers suggest that, despite its name, a regulatory protein called inhibitor-2 helps promote PP1 activity in neurons. Together, these findings significantly extend our understanding of how PP1 is regulated in the context of synaptic plasticity.


More Press
AAAS and EurekAlert sent out a Public release: memory_how_neurons_activate_pp1-122323

Focus on neuroscience could lead to treatments, economic development for New Orleans: Nicolas Bazan

Neuroscience focus will lead to medical, economic advances

2013 summer students Doctors assisted by artist in study of brain illness
Artist in Residence Taryn M. Nicoll at the Neuroscience Center of Excellence

Chancellor's Notes - NCE SUN 2013 SUN Students 

Could Charity Hospital become a world brain health center ...
Dr. Nicolas G. Bazan interviewed on the repurpose of Charity Hospital in New Orleans as an integrated brain research and treatment center

LSU MD named editor in chief of World Federation of Neurology journal; names 2 sub-editors
THE ASSOCIATED PRESS June 14, 2013 - 4:08 am EDT

NEW ORLEANS — Three scientists at the LSU Health Sciences Center New Orleans School of Medicine have been named editors of the Journal of the Neurological Sciences — the official journal of the World Federation of Neurology. The medical school says Dr. John D. England, the head of neurology, has been named editor in chief for a five-year term starting July 1. England says the appointment could be renewed for another five years. He named Dr. Nicolas Bazan, who is the director of the hospital's Neuroscience Center of Excellence, as associate editor for basic and translational sciences. He also appointed Nicole Villemarette-Pittman, the school's administrative director for neurology research development, as managing editor in New Orleans. The World Federation of Neurology represents 114 professional societies in 113 countries worldwide.


Brain awareness week

Kids Learning About the Brain!

Sonia Gasparini, Ph.D. (Cell Biology and Anatomy)

On March 9th, faculty, postdoctoral researchers, and students from the LSUHSC and Tulane Neuroscience Programs volunteered their time to unravel the mysteries of brain functions at the event “Your Sensational Brain” held at the Children Resource Center (913 Napoleon Ave). This is an annual outreach program held to celebrate Brain Awareness Week, a global campaign to increase awareness about the benefits of brain and nervous system research. About 40 children, parents, and teachers enjoyed the interactive activities and asked several questions during the two-hour event, which was free and open to the public and geared to children 5 - 12 years of age. The activities, coordinated by Dr. Sonia Gasparini of the Neuroscience Center and sponsored by the Greater New Orleans chapter of the Society for Neuroscience included:
• Show and tell of real brains and brain and neuron models

• Show and tell of brain slices and stained neurons under a microscope

• Demonstration of the knee jerk reflex, with children “behaving like neurons”
(photo by Leslie Capo)


2013 3:39:55 PM

What is new with the brain and docosanoids? - Prof. Nicolas Bazan

Dr. Nicolas Bazan honored at ISN and ASN conference
in Cancun, Mexico held April 17-19, 2013

Top Addiction Specialist Raises Awareness
Dr. Luigi Pulvirenti, professor of neuropharmacology
and President and Scientific Director at the
Neuroscience School of Advanced Studies in Cortona, Italy
Link to article

Children taught about brains
Link to article


2013 2:36:22 PM

Dr. Hamilton Farris, Mette Flatt, Dr. William Gordon (back),
Dr. Jennifer Lentz, and Dr. Nicolas Bazan (the medical research team)

Local medical research team makes breakthrough in curing deafness
Link to Dr. Jennifer Lentz's article

Dr. Minghao Jin, Ophthalmology and Neuroscience, identified a protein that protects retinal photoreceptor cells from degeneration
caused by light damage. This result may provide a new therapeutic target for both an inherited retinal degenerative disease and age-related macular
degeneration. (Li, S, et al., “Fatty Acid Transport Protein 4 (FATP4) Prevents Light-Induced Degeneration of Cone and Rod Photoreceptors by Inhibiting
RPE65 Isomerase” J Neurosci. 2013 Feb 13;33(7):3178-89)

Changing the way the world does research/The Scientist
link to Dr. Bazan's article

Balanced Body and Brain: A FOX 8 special report
Link to interview

Neuroscience Center of Excellence Gala Fundraiser with Placido Domingo
Link to article from Times Picayune/Neustro Pueblo

Fish oil helped save our son
Link to article on CNN

Dr. Chu Chen has identified a new therapeutic target for prevention and treatment of Alzheimer's disease.
This work was published online in Cell Reports, a Cell Press journal
The Cell Press Office selected this outstanding  paper for a press release.
This major  discovery has been covered by lots of news media.
Link to Chancellor's Notes with article about Dr. Chen's discovery

Neuroscience in Action Chancellor's Notes 041312
Dr. Sonia Gasparini led the event "Your Sensational Brain" for 40 children ages 3-15 read more

Dr. Walter J. Lukiw, LSU Neuroscience Center, recently interviewed by
Genetic Engineering and Biotechnology News magazine, discusses his lab's
recent work on micro RNA (miRNA) and its therapeutic potential in treating neurodegenerative disease Feb 15, 2012 (Vol. 32, No. 4)

Neuroscience Center of Excellence in Chancellor's Notes November 11, 2011
LSU Salutes its Veterans with our own Ryan Labadens, 4th row, second in and the Neuroscience Center of Excellence sponsored the 10th Annual FACS meeting with over 60 scientists attending from around the world for the latest on fish oil

Links to Interviews:

Researchers in Town to Share Discoveries on Brain Injuries SFN Convention 2012
Link to interview with Dr. Bazan and other Neuroscientists  WWL-TV

Study: Smoking during pregnancy could lead to child's weight, drug issues
Fish Oil/WWL-TV

The Arts of Neuroscientists: Nicolas Bazan - Dana Foundation
The Dana Alliance for Brain Initiatives, a nonprofit organization of more than 300 leading neuroscientists, works to advance public awareness about the progress

New Study Backs Up Benefits of Fish Oil Supplements Meg Farris/WWL-TV 091212

DHA: A Sentinel for Neuroprotection and Brain Repair
Global Organization for EPA and DHA (GOED) Exchange June 8, 2012

Early History of Omega-3 Research, Boston, Massachusetts

Protect your vision by altering your diet: Molly Kimball, The Times Picayune, 031612

Dr. Isabel Univision National Radio Show - 2/29/12- Listen by clicking here:

Turn On Your Inner Light Radio Show - 2/21/12- Listen by clicking here:

Steve Gleason's plight focuses attention on ALS - 092611

A new discovery could reverse the effects of a stroke - 061711

Stopping Stroke Damage with a Shot - 061511

Ground breaks on new teaching hospital - 041811

Featured videos - 111010
Medical watch: for some could tanning be an addiction?
New discovery from a local doctor that may help people suffering from a stroke

Omega 3 fatty acids may help prevent Alzheimer's - 091610

Audio Interview with Dr. Nicolas Bazan - 060509

Impact of brain disease on families - 012209

Older Neuroscience Center of Excellence Articles

Nicolas Bazan, Times-Picayune, 2010

Nicolas Bazan City Business Health Care Heros 2008

Nicolas Bazan, no date

This Week's Citation Classic, 1991

Rx for Innovation, Louisiana Technology Guide,

Cornerstone Bazan Superchair 2005

Repairing the Brain 2004

EPScOR article, 2004

Licensed to Deal, New Orleans City Business, 2004

NB Bio Biz Enters City Test Tube, New Orleans City Business 2004

Hispanic Heritage 2003

Walter Lukiw, Invited Lectures 2003

Thinking Small, Advocate, 2003

Nicolas Bazan, La Prensa Rich Discoveries, 2002

Molecular Neurobiology 15th Anniversary, 2002

Dr. Feelgood, Forbes, 2002

Dr. Nicolas G. Bazan, New Orleans Magazine People to Watch, 2002

Researcher Analyzes Last Frontier: The Brain, Times-Picayune, 2002

Innovator of the Year, New Orleans City Business, 2002

The Most Influential, La Prensa, 2002

Nicolas Bazan, university scientists get federal money to think small 2001

Local Investor puts 4 million into Fledgling Drug Company, New Orleans City Business, 2000

Changing the Way the World Does Research, Times Picayune, 1999

Probing the Depths, New Orleans City Business, 1998

The Brain: Last Frontier of Medicine, Advocate, 1997

Drug May Halt Damage to Brain, Times Picayune, 1997

The Bazan Approach, HealthCare New Orleans, 1995

Neuroscience Center Seen as a Boost to Medicine and to Economy, New Orleans City Business, 1993

LSU Opens New Labs for Neurosciences, Times Picayune

Develop Patents, Times Picayune, 1989