School of Medicine

Comprehensive Alcohol Research Center




New insights into the mechanism of alcohol-mediated organ damage via its impact on immunity, metabolism, and repair pathways: A summary of the 2021 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

Khair S, Brenner LA, Koval M, Samuelson D, Cucinello-Regland JA, Anton P, Piano MR, Simon L, Crotty K, Sharieh F, Travers JB, Singh V, Cannon A, Kim A, McCullough RL, Yeligar SM, Wyatt TA, McMahan RH, Choudhry MA, Kovacs EJ.

Alcohol. 2022 Sep;103:1-7. doi: 10.1016/j.alcohol.2022.05.004. Epub 2022 Jun 1. PMID: 35659577.

Chronic Binge Alcohol and Ovarian Hormone Loss Dysregulate Circulating Immune Cell SIV Co-Receptor Expression and Mitochondrial Homeostasis in SIV-Infected Rhesus Macaques.

McTernan PM, Siggins RW, Catinis A, Amedee AM, Simon L, Molina PE.

Biomolecules. 2022 Jul 5;12(7):946. doi: 10.3390/biom12070946. PMID: 35883501.

Cross sectional analysis of the effect of alcohol on pulmonary function in a cohort of men and women living with HIV.

Zifodya JS, Ferguson TF, Siggins RW, Brashear MM, Kantrow SP, Nelson S, Shellito JE, Molina PE, Welsh DA.

Alcohol. 2022 Jun;101:45-51. doi: 10.1016/j.alcohol.2022.03.001. Epub 2022 Mar 16. PMID: 35306109.

Host innate and adaptive immunity shapes the gut microbiota biogeography.

Gu M, Samuelson DR, de la Rua NM, Charles TP, Taylor CM, Luo M, Siggins RW, Shellito JE, Welsh DA.

Microbiol Immunol. 2022 Jun;66(6):330-341. doi: 10.1111/1348-0421.12963. Epub 2022 May 26. PMID: 35067963.

Alcohol Impairs Immunometabolism and Promotes Naïve T Cell Differentiation to Pro-Inflammatory Th1 CD4+ T Cells.

McTernan PM, Levitt DE, Welsh DA, Simon L, Siggins RW, Molina PE.

Front Immunol. 2022 May 12;13:839390. doi: 10.3389/fimmu.2022.839390. eCollection 2022. PMID: 35634279.

Associations of Binge Drinking and Heavy Alcohol Use on Sugar and Fat Intake in a Cohort of Southern People Living with HIV.

Rosen EM, Primeaux SD, Simon L, Welsh DA, Molina PE, Ferguson TF.

Alcohol Alcohol. 2022 Mar 12;57(2):226-233. doi: 10.1093/alcalc/agab066. PMID: 34611697.

A review of alcohol-pathogen interactions: New insights into combined disease pathomechanisms.

Osna NA, New-Aaron M, Dagur RS, Thomes P, Simon L, Levitt D, McTernan P, Molina PE, Choi HY, Machida K, Sherman KE, Riva A, Phillips S, Chokshi S, Kharbanda KK, Weinman S, Ganesan M.

Alcohol Clin Exp Res. 2022 Mar;46(3):359-370. doi: 10.1111/acer.14777. Epub 2022 Feb 6. PMID: 35076108.

Alcohol-Associated Tissue Injury: Current Views on Pathophysiological Mechanisms.

Simon L, Souza-Smith FM, Molina PE.

Annu Rev Physiol. 2022 Feb 10;84:87-112. doi: 10.1146/annurev-physiol-060821-014008. PMID: 35143331.

Pathophysiological Consequences of At-Risk Alcohol Use; Implications for Comorbidity Risk in Persons Living With Human Immunodeficiency Virus.

Simon L, Edwards S, Molina PE.

Front Physiol. 2022 Jan 18;12:758230. doi: 10.3389/fphys.2021.758230. eCollection 2021. PMID: 35115952.

The Convergent Neuroscience of Affective Pain and Substance Use Disorder.

Pahng AR, Edwards S.

Alcohol Res. 2021 Dec 16;41(1):14. doi: 10.35946/arcr.v41.1.14. eCollection 2021. PMID: 34976573.

Chronic binge alcohol and ovariectomy-mediated impaired insulin responsiveness in SIV-infected female rhesus macaques.

Simon L, Torres D, Saravia A, Levitt DE, Vande Stouwe C, McGarrah H, Coleman L, Dufour JP, Amedee AM, Molina PE.

Am J Physiol Regul Integr Comp Physiol. 2021 Nov 1;321(5):R699-R711. doi: 10.1152/ajpregu.00159.2021. Epub 2021 Sep 15. PMID: 34524906.


Comprehensive Assessment of Alcohol Consumption in People Living with HIV (PLWH): The New Orleans Alcohol Use in HIV Study.

Ferguson TF, Theall KP, Brashear M, Maffei V, Beauchamp A, Siggins RW, Simon L, Mercante D, Nelson S, Welsh DA, Molina PE.

Alcohol Clin Exp Res. 2020 Jun;44(6):1261-1272. doi: 10.1111/acer.14336. Epub 2020 May 22. PMID: 32441814.

Adverse Childhood Experiences, Smoking and Alcohol Use, and Allostatic Load Among People Living with HIV.

Wallace M, Felker-Kantor E, Madkour A, Ferguson T, Welsh D, Molina P, Theall KP.

AIDS Behav. 2020 Jun;24(6):1653-1662. doi: 10.1007/s10461-019-02684-5. PMID: 31559525.

Lifetime alcohol use among persons living with HIV is associated with frailty.

Maffei VJ, Ferguson TF, Brashear MM, Mercante DE, Theall KP, Siggins RW, Taylor CM, Molina P, Welsh DA.

AIDS. 2020 Feb 1;34(2):245-254. doi: 10.1097/QAD.0000000000002426. PMID: 31714352.

HEMA 3 Staining: A Simple Alternative for the Assessment of Myoblast Differentiation.

Levitt DE, Adler KA, Simon L.

Curr Protoc Stem Cell Biol. 2019 Dec;51(1):e101. doi: 10.1002/cpsc.101. PMID: 31756292.

HIV Stigma, Mental Health, and Alcohol Use Disorders among People Living with HIV/AIDS in New Orleans.

Felker-Kantor EA, Wallace ME, Madkour AS, Duncan DT, Andrinopoulos K, Theall K.

J Urban Health. 2019 Dec;96(6):878-888. doi: 10.1007/s11524-019-00390-0. PMID: 31520231.

Neighborhood Alcohol Environment: Differential Effects on Hazardous Drinking and Mental Health by Sex in Persons Living with HIV (PLWH).

Theall KP, Wallace M, Felker-Kantor E, Madkour AS, Brashear M, Ferguson T, Welsh D, Molina P.

AIDS Behav. 2019 Dec;23(12):3237-3246. doi: 10.1007/s10461-019-02632-3. PMID: 31401740.

Reduced Serum Osteocalcin in High-Risk Alcohol Using People Living With HIV Does Not Correlate With Systemic Oxidative Stress or Inflammation: Data From the New Orleans Alcohol Use in HIV Study.

Watt J, Schuon J, Davis J, Ferguson TF, Welsh DA, Molina PE, Ronis MJJ.

Alcohol Clin Exp Res. 2019 Nov;43(11):2374-2383. doi: 10.1111/acer.14186. Epub 2019 Oct 1. PMID: 31483873.

Alcohol consumption increases susceptibility to pneumococcal pneumonia in a humanized murine HIV model mediated by intestinal dysbiosis.

Samuelson DR, Siggins RW, Ruan S, Amedee AM, Sun J, Zhu QK, Marasco WA, Taylor CM, Luo M, Welsh DA, Shellito JE.

Alcohol. 2019 Nov;80:33-43. doi: 10.1016/j.alcohol.2018.08.012. Epub 2018 Sep 11. PMID: 30213614.

"Housing Insecurity Seems to Almost Go Hand in Hand with Being Trans": Housing Stress among Transgender and Gender Non-conforming Individuals in New Orleans.

Glick JL, Lopez A, Pollock M, Theall KP.

J Urban Health. 2019 Oct;96(5):751-759. doi: 10.1007/s11524-019-00384-y. PMID: 31529193.

Intestinal Microbial Products From Alcohol-Fed Mice Contribute to Intestinal Permeability and Peripheral Immune Activation.

Samuelson DR, Gu M, Shellito JE, Molina PE, Taylor CM, Luo M, Welsh DA.

Alcohol Clin Exp Res. 2019 Oct;43(10):2122-2133. doi: 10.1111/acer.14176. Epub 2019 Sep 5. PMID: 31407808.

Epigenomic mechanisms of alcohol-induced impaired differentiation of skeletal muscle stem cells; role of Class IIA histone deacetylases.

Adler K, Molina PE, Simon L.

Physiol Genomics. 2019 Sep 1;51(9):471-479. doi: 10.1152/physiolgenomics.00043.2019. Epub 2019 Aug 9. PMID: 31398085.

Childhood obesity and the associated roles of neighborhood and biologic stress.

Theall KP, Chaparro MP, Denstel K, Bilfield A, Drury SS.

Prev Med Rep. 2019 Mar 18;14:100849. doi: 10.1016/j.pmedr.2019.100849. eCollection 2019 Jun. PMID: 30956941.

Prevalence of non-tuberculous mycobacteria in HIV-infected patients admitted to hospital with pneumonia.

Lapinel NC, Jolley SE, Ali J, Welsh DA.

Int J Tuberc Lung Dis. 2019 Apr 1;23(4):491-497. doi: 10.5588/ijtld.18.0336. PMID: 31064629.

The New Orleans Alcohol Use in HIV Study: Launching a Translational Investigation of the Interaction of Alcohol Use with Biological and Socioenvironmental Risk Factors for Multimorbidity in People Living with HIV.

Welsh DA, Ferguson T, Theall KP, Simon L, Amedee A, Siggins RW, Nelson S, Brashear M, Mercante D, Molina PE.

Alcohol Clin Exp Res. 2019 Apr;43(4):704-709. doi: 10.1111/acer.13980. Epub 2019 Mar 10. PMID: 30748025.

Chronic Binge Alcohol-Associated Differential Brain Region Modulation of Growth Factor Signaling Pathways and Neuroinflammation in Simian Immunodeficiency Virus-Infected Male Macaques.

Maxi JK, Mercante D, Foret B, Oberhelman S, Ferguson TF, Bagby GJ, Nelson S, Amedee AM, Edwards S, Simon L, Molina PE.

Alcohol Alcohol. 2019 Jan 9;54(5):477-486. doi: 10.1093/alcalc/agz056. PMID: 31322648.

Substance use is independently associated with pneumonia severity in persons living with the human immunodeficiency virus (HIV).

Jolley SE, Welsh DA.

Subst Abus. 2019;40(2):256-261. doi: 10.1080/08897077.2019.1576088. Epub 2019 Mar 18. PMID: 30883265.


For data's sake: dilemmas in the measurement of gender minorities.

Glick JL, Theall K, Andrinopoulos K, Kendall C.

Cult Health Sex. 2018 Dec;20(12):1362-1377. doi: 10.1080/13691058.2018.1437220. Epub 2018 Mar 13. PMID: 29533145.

"Tiptoeing Around the System": Alternative Healthcare Navigation Among Gender Minorities in New Orleans.

Glick JL, Andrinopoulos KM, Theall KP, Kendall C.

Transgend Health. 2018 Jul 1;3(1):118-126. doi: 10.1089/trgh.2018.0015. eCollection 2018. PMID: 30014040.

Considering high alcohol and violence neighborhood context using daily diaries and GPS: A pilot study among people living with HIV.

Theall KP, Felker-Kantor E, Wallace M, Zhang X, Morrison CN, Wiebe DJ.

Drug Alcohol Depend. 2018 Jun 1;187:236-241. doi: 10.1016/j.drugalcdep.2018.03.005. Epub 2018 Apr 10. PMID: 29684891.

The Role of Discrimination in Care Postponement Among Trans-Feminine Individuals in the U.S. National Transgender Discrimination Survey.

Glick JL, Theall KP, Andrinopoulos KM, Kendall C.

LGBT Health. 2018 Apr;5(3):171-179. doi: 10.1089/lgbt.2017.0093. Epub 2018 Mar 28. PMID: 29589995.

Myoblast mitochondrial respiration is decreased in chronic binge alcohol administered simian immunodeficiency virus-infected antiretroviral-treated rhesus macaques.

Duplanty AA, Siggins RW, Allerton T, Simon L, Molina PE.

Physiol Rep. 2018 Mar;6(5):e13625. doi: 10.14814/phy2.13625. PMID: 29504290.

Summary of the 2016 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

Boule LA, Ju C, Agudelo M, Parira T, Cannon A, Davis B, Eby J, Cresci G, Samuelson DR, Shukla P, Alrefai WA, Sureshchandra S, Pandey SC, Schnabl B, Curtis BJ, Wyatt TA, Choudhry MA, Kovacs EJ.

Alcohol. 2018 Feb;66:35-43. doi: 10.1016/j.alcohol.2017.07.005. Epub 2017 Sep 23. PMID: 29127885.

Simian Immunodeficiency Virus Infection Increases Blood Ethanol Concentration Duration After Both Acute and Chronic Administration.

Simon L, Siggins R, Winsauer P, Brashear M, Ferguson T, Mercante D, Song K, Vande Stouwe C, Nelson S, Bagby G, Amedee A, Molina PE.

AIDS Res Hum Retroviruses. 2018 Feb;34(2):178-184. doi: 10.1089/AID.2017.0195. Epub 2017 Nov 21. PMID: 29037050.

The respiratory tract microbial biogeography in alcohol use disorder.

Samuelson DR, Burnham EL, Maffei VJ, Vandivier RW, Blanchard EE, Shellito JE, Luo M, Taylor CM, Welsh DA.

Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L107-L117. doi: 10.1152/ajplung.00277.2017. Epub 2017 Aug 31. PMID: 28860145.

Biological Aging and the Human Gut Microbiota.

Maffei VJ, Kim S, Blanchard E 4th, Luo M, Jazwinski SM, Taylor CM, Welsh DA.

J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1474-1482. doi: 10.1093/gerona/glx042. PMID: 28444190.

Changes in the gut microbial communities following addition of walnuts to the diet.

Byerley LO, Samuelson D, Blanchard E 4th, Luo M, Lorenzen BN, Banks S, Ponder MA, Welsh DA, Taylor CM.

J Nutr Biochem. 2017 Oct;48:94-102. doi: 10.1016/j.jnutbio.2017.07.001. Epub 2017 Jul 9. PMID: 28797931.

Living in violence: Neighborhood domestic violence and small for gestational age births.

Felker-Kantor E, Wallace M, Theall K.

Health Place. 2017 Jul;46:130-136. doi: 10.1016/j.healthplace.2017.05.011. Epub 2017 May 17. PMID: 28527328.

Beyond Food Access: The Impact of Parent-, Home-, and Neighborhood-Level Factors on Children's Diets.

Futrell Dunaway L, Carton T, Ma P, Mundorf AR, Keel K, Theall KP.

Int J Environ Res Public Health. 2017 Jun 20;14(6):662. doi: 10.3390/ijerph14060662. PMID: 28632162.

Alcohol-associated intestinal dysbiosis impairs pulmonary host defense against Klebsiella pneumoniae.

Samuelson DR, Shellito JE, Maffei VJ, Tague ED, Campagna SR, Blanchard EE, Luo M, Taylor CM, Ronis MJJ, Molina PE, Welsh DA.

PLoS Pathog. 2017 Jun 12;13(6):e1006426. doi: 10.1371/journal.ppat.1006426. eCollection 2017 Jun. PMID: 28604843.

Non-canonical Glucocorticoid Receptor Transactivation of gilz by Alcohol Suppresses Cell Inflammatory Response.

Ng HP, Jennings S, Wang J, Molina PE, Nelson S, Wang G.

Front Immunol. 2017 Jun 7;8:661. doi: 10.3389/fimmu.2017.00661. eCollection 2017. PMID: 28638383.

The differential impact of oxytocin receptor gene in violence-exposed boys and girls.

Merrill LC, Jones CW, Drury SS, Theall KP.

Int J Dev Neurosci. 2017 Jun;59:60-67. doi: 10.1016/j.ijdevneu.2017.03.009. Epub 2017 Mar 22. PMID: 28341538.

Chronic Binge Alcohol-Induced Dysregulation of Mitochondrial-Related Genes in Skeletal Muscle of Simian Immunodeficiency Virus-Infected Rhesus Macaques at End-Stage Disease.

Duplanty AA, Simon L, Molina PE.

Alcohol Alcohol. 2017 May 1;52(3):298-304. doi: 10.1093/alcalc/agw107. PMID: 28069597.

The Prefrontal Cortex as a Critical Gate of Negative Affect and Motivation in Alcohol Use Disorder.

Pahng AR, McGinn MA, Paulsen RI, Edwards S.

Curr Opin Behav Sci. 2017 Feb;13:139-143. doi: 10.1016/j.cobeha.2016.11.004. PMID: 28111628.

B cell and antibody responses in mice induced by a putative cell surface peptidase of Pneumocystis murina protect against experimental infection.

Ruan S, Cai Y, Ramsay AJ, Welsh DA, Norris K, Shellito JE.

Vaccine. 2017 Jan 23;35(4):672-679. doi: 10.1016/j.vaccine.2016.11.073. Epub 2016 Dec 21. PMID: 28012778.

Association Between Neighborhood Violence and Biological Stress in Children.

Theall KP, Shirtcliff EA, Dismukes AR, Wallace M, Drury SS.

JAMA Pediatr. 2017 Jan 1;171(1):53-60. doi: 10.1001/jamapediatrics.2016.2321. PMID: 27842189.

Obese ZDF rats fermented resistant starch with effects on gut microbiota but no reduction in abdominal fat.

Goldsmith F, Guice J, Page R, Welsh DA, Taylor CM, Blanchard EE, Luo M, Raggio AM, Stout RW, Carvajal-Aldaz D, Gaither A, Pelkman C, Ye J, Martin RJ, Geaghan J, Durham HA, Coulon D, Keenan MJ.

Mol Nutr Food Res. 2017 Jan;61(1):10.1002/mnfr.201501025. doi: 10.1002/mnfr.201501025. Epub 2016 Aug 11. PMID: 27234399.

Chronic Binge Alcohol Administration Dysregulates Hippocampal Genes Involved in Immunity and Neurogenesis in Simian Immunodeficiency Virus-Infected Macaques.

Maxi JK, Dean M, Zabaleta J, Reiss K, Bagby GJ, Nelson S, Winsauer PJ, Peruzzi F, Molina PE.

Biomolecules. 2016 Nov 9;6(4):43. doi: 10.3390/biom6040043. PMID: 27834864.

Mechanisms Involved in Disruption of Adipose Tissue Mass Resulting from Chronic Unhealthy Alcohol Consumption.

Molina PE.

Alcohol Clin Exp Res. 2016 Nov;40(11):2296-2298. doi: 10.1111/acer.13219. Epub 2016 Sep 26. PMID: 27716963.

Chronic binge alcohol administration impairs glucose-insulin dynamics and decreases adiponectin in asymptomatic simian immunodeficiency virus-infected macaques.

Ford SM Jr, Simon L, Vande Stouwe C, Allerton T, Mercante DE, Byerley LO, Dufour JP, Bagby GJ, Nelson S, Molina PE.

Am J Physiol Regul Integr Comp Physiol. 2016 Nov 1;311(5):R888-R897. doi: 10.1152/ajpregu.00142.2016. Epub 2016 Sep 7. PMID: 27605560.

Analysis of the intestinal microbial community and inferred functional capacities during the host response to Pneumocystis pneumonia.

Samuelson DR, Charles TP, de la Rua NM, Taylor CM, Blanchard EE, Luo M, Shellito JE, Welsh DA.

Exp Lung Res. 2016 Oct-Dec;42(8-10):425-439. doi: 10.1080/01902148.2016.1258442. Epub 2016 Dec 7. PMID: 27925857.

Validation of RPS13 as a reference gene for absolute quantification of SIV RNA in tissue of rhesus macaques.

Robichaux S, Lacour N, Bagby GJ, Amedee AM.

J Virol Methods. 2016 Oct;236:245-251. doi: 10.1016/j.jviromet.2016.08.004. Epub 2016 Aug 7. PMID: 27510462.

Presence of an Alcohol Use Disorder is Associated with Greater Pneumonia Severity in Hospitalized HIV-Infected Patients.

Jolley SE, Alkhafaf Q, Hough C, Welsh DA.

Lung. 2016 Oct;194(5):755-62. doi: 10.1007/s00408-016-9920-1. Epub 2016 Jul 12. PMID: 27405853.

Chronic Δ(9)-Tetrahydrocannabinol Administration Reduces IgE(+)B Cells but Unlikely Enhances Pathogenic SIVmac251 Infection in Male Rhesus Macaques of Chinese Origin.

Wei Q, Liu L, Cong Z, Wu X, Wang H, Qin C, Molina P, Chen Z.

J Neuroimmune Pharmacol. 2016 Sep;11(3):584-591. doi: 10.1007/s11481-016-9674-9. Epub 2016 Apr 25. PMID: 27109234.

Reply to: High-Fat Diet-Induced Dysbiosis as a Cause of Neuroinflammation.

Bruce-Keller AJ, Salbaum JM, Luo M, Blanchard E 4th, Taylor CM, Welsh DA, Berthoud HR.

Biol Psychiatry. 2016 Jul 1;80(1):e5-6. doi: 10.1016/j.biopsych.2015.11.006. Epub 2015 Nov 17. PMID: 26774965.

Role of Direct and Indirect Violence Exposure on Externalizing Behavior in Children.

Fleckman JM, Drury SS, Taylor CA, Theall KP.

J Urban Health. 2016 Jun;93(3):479-92. doi: 10.1007/s11524-016-0052-y. PMID: 27184572.

Sex and the Lab: An Alcohol-Focused Commentary on the NIH Initiative to Balance Sex in Cell and Animal Studies.

Guizzetti M, Davies DL, Egli M, Finn DA, Molina P, Regunathan S, Robinson DL, Sohrabji F.

Alcohol Clin Exp Res. 2016 Jun;40(6):1182-91. doi: 10.1111/acer.13072. Epub 2016 May 7. PMID: 27154003.

CD4(+) T-Cell-Independent Secondary Immune Responses to Pneumocystis Pneumonia.

de la Rua NM, Samuelson DR, Charles TP, Welsh DA, Shellito JE.

Front Immunol. 2016 May 11;7:178. doi: 10.3389/fimmu.2016.00178. eCollection 2016. PMID: 27242785.

Oral Immunization of Mice with Live Pneumocystis murina Protects against Pneumocystis Pneumonia.

Samuelson DR, de la Rua NM, Charles TP, Ruan S, Taylor CM, Blanchard EE, Luo M, Ramsay AJ, Shellito JE, Welsh DA.

J Immunol. 2016 Mar 15;196(6):2655-65. doi: 10.4049/jimmunol.1502004. Epub 2016 Feb 10. PMID: 26864029.

Δ9-Tetrahydrocannabinol (Δ9-THC) Promotes Neuroimmune-Modulatory MicroRNA Profile in Striatum of Simian Immunodeficiency Virus (SIV)-Infected Macaques.

Simon L, Song K, Vande Stouwe C, Hollenbach A, Amedee A, Mohan M, Winsauer P, Molina P.

J Neuroimmune Pharmacol. 2016 Mar;11(1):192-213. doi: 10.1007/s11481-015-9645-6. Epub 2015 Nov 25. PMID: 26607731.

Racial Discrimination and HIV-related Risk Behaviors in Southeast Louisiana.

Kaplan KC, Hormes JM, Wallace M, Rountree M, Theall KP.

Am J Health Behav. 2016 Jan;40(1):132-43. doi: 10.5993/AJHB.40.1.15. PMID: 26685822.

Chronic binge alcohol administration dysregulates global regulatory gene networks associated with skeletal muscle wasting in simian immunodeficiency virus-infected macaques.

Simon L, Hollenbach AD, Zabaleta J, Molina PE.

BMC Genomics. 2015 Dec 23;16:1097. doi: 10.1186/s12864-015-2329-z. PMID: 26699868.

Chronic alcohol increases CD8+ T-cell immunosenescence in simian immunodeficiency virus-infected rhesus macaques.

Katz PS, Siggins RW, Porretta C, Armstrong ML, Zea AH, Mercante DE, Parsons C, Veazey RS, Bagby GJ, Nelson S, Molina PE, Welsh DA.

Alcohol. 2015 Dec;49(8):759-65. doi: 10.1016/j.alcohol.2015.09.003. Epub 2015 Oct 27. PMID: 26603633.

Characterization of the Genital Microenvironment of Female Rhesus Macaques Prior to and After SIV Infection.

Nichols WA, Birke L, Dufour J, Loganantharaj N, Bagby GJ, Nelson S, Molina PE, Amedee AM.

Am J Reprod Immunol. 2015 Dec;74(6):508-22. doi: 10.1111/aji.12422. Epub 2015 Aug 20. PMID: 26290147.

Regulation of lung immunity and host defense by the intestinal microbiota.

Samuelson DR, Welsh DA, Shellito JE.

Front Microbiol. 2015 Oct 7;6:1085. doi: 10.3389/fmicb.2015.01085. eCollection 2015. PMID: 26500629.

Chronic Binge Alcohol Administration Increases Intestinal T-Cell Proliferation and Turnover in Rhesus Macaques.

Veazey RS, Amedee A, Wang X, Bernice Kaack M, Porretta C, Dufour J, Welsh D, Happel K, Pahar B, Molina PE, Nelson S, Bagby GJ.

Alcohol Clin Exp Res. 2015 Aug;39(8):1373-9. doi: 10.1111/acer.12784. Epub 2015 Jul 4. PMID: 26146859.

Impact of a community popular opinion leader intervention among African American adults in a southeastern United States community.

Theall KP, Fleckman J, Jacobs M.

AIDS Educ Prev. 2015 Jun;27(3):275-87. doi: 10.1521/aeap.2015.27.3.275. PMID: 26010317.

Behavioral, Metabolic, and Immune Consequences of Chronic Alcohol or Cannabinoids on HIV/AIDs: Studies in the Non-Human Primate SIV Model.

Molina PE, Amedee AM, Winsauer P, Nelson S, Bagby G, Simon L.

J Neuroimmune Pharmacol. 2015 Jun;10(2):217-32. doi: 10.1007/s11481-015-9599-8. Epub 2015 Mar 21. PMID: 25795088.

Ethanol impairs mucosal immunity against Streptococcus pneumoniae infection by disrupting interleukin 17 gene expression.

Trevejo-Nunez G, Chen K, Dufour JP, Bagby GJ, Horne WT, Nelson S, Kolls JK.

Infect Immun. 2015 May;83(5):2082-8. doi: 10.1128/IAI.02869-14. Epub 2015 Mar 9. PMID: 2575420.

Obese-type gut microbiota induce neurobehavioral changes in the absence of obesity.

Bruce-Keller AJ, Salbaum JM, Luo M, Blanchard E 4th, Taylor CM, Welsh DA, Berthoud HR.

Biol Psychiatry. 2015 Apr 1;77(7):607-15. doi: 10.1016/j.biopsych.2014.07.012. Epub 2014 Jul 18. PMID: 25173628.

Chronic administration of Δ9-tetrahydrocannabinol induces intestinal anti-inflammatory microRNA expression during acute simian immunodeficiency virus infection of rhesus macaques.

Chandra LC, Kumar V, Torben W, Vande Stouwe C, Winsauer P, Amedee A, Molina PE, Mohan M.

J Virol. 2015 Jan 15;89(2):1168-81. doi: 10.1128/JVI.01754-14. Epub 2014 Nov 5. PMID: 25378491.

Advancing Behavioral HIV Prevention: Adapting an Evidence-Based Intervention for People Living with HIV and Alcohol Use Disorders.

Armstrong ML, LaPlante AM, Altice FL, Copenhaver M, Molina PE.

AIDS Res Treat. 2015;2015:879052. doi: 10.1155/2015/879052. Epub 2015 Dec 1. PMID: 26697216.

Alcohol and HIV Effects on the Immune System.

Bagby GJ, Amedee AM, Siggins RW, Molina PE, Nelson S, Veazey RS.

Alcohol Res. 2015;37(2):287-97. PMID: 26695751.

Serum and bal beta-D-glucan for the diagnosis of Pneumocystis pneumonia in HIV positive patients.

Salerno D, Mushatt D, Myers L, Zhuang Y, de la Rua N, Calderon EJ, Welsh DA.

Respir Med. 2014 Nov;108(11):1688-95. doi: 10.1016/j.rmed.2014.09.017. PMID: 25448310.

Chronic binge alcohol administration accentuates expression of pro-fibrotic and inflammatory genes in the skeletal muscle of simian immunodeficiency virus-infected macaques.

Dodd T, Simon L, LeCapitaine NJ, Zabaleta J, Mussell J, Berner P, Ford S, Dufour J, Bagby GJ, Nelson S, Molina PE.

Alcohol Clin Exp Res. 2014 Nov;38(11):2697-706. doi: 10.1111/acer.12545. PMID: 25421506.

Chronic binge alcohol increases susceptibility to rectal simian immunodeficiency virus infection in macaques.

Amedee AM, Veazey R, Molina P, Nelson S, Bagby GJ.

AIDS. 2014 Oct 23;28(16):2485-7. doi: 10.1097/QAD.0000000000000413. PMID: 25265232.

Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function.

Brown AO, Mann B, Gao G, Hankins JS, Humann J, Giardina J, Faverio P, Restrepo MI, Halade GV, Mortensen EM, Lindsey ML, Hanes M, Happel KI, Nelson S, Bagby GJ, Lorent JA, Cardinal P, Granados R, Esteban A, LeSaux CJ, Tuomanen EI, Orihuela CJ.

PLoS Pathog. 2014 Sep 18;10(9):e1004383. doi: 10.1371/journal.ppat.1004383. eCollection 2014 Sep. PMID: 25232870.

Chronic binge alcohol consumption does not diminish effectiveness of continuous antiretroviral suppression of viral load in simian immunodeficiency virus-infected macaques.

Molina PE, Amedee AM, Veazey R, Dufour J, Volaufova J, Bagby GJ, Nelson S.

Alcohol Clin Exp Res. 2014 Sep;38(9):2335-44. doi: 10.1111/acer.12507. PMID: 25257285.

The effects of chronic binge alcohol on the genital microenvironment of simian immunodeficiency virus-infected female rhesus macaques.

Loganantharaj N, Nichols WA, Bagby GJ, Volaufova J, Dufour J, Martin DH, Nelson S, Amedee AM.

AIDS Res Hum Retroviruses. 2014 Aug;30(8):783-91. doi: 10.1089/AID.2014.0065. Epub 2014 Jul 8. PMID: 24902876.

Dysregulation of myelopoiesis by chronic alcohol administration during early SIV infection of rhesus macaques.

Siggins RW, Molina P, Zhang P, Bagby GJ, Nelson S, Dufour J, LeCapitaine NJ, Walsh C, Welsh DA.

Alcohol Clin Exp Res. 2014 Jul;38(7):1993-2000. doi: 10.1111/acer.12433. Epub 2014 Jun 18. PMID: 24942272.

Coordinated histone H3 methylation and acetylation regulate physiologic and pathologic fas ligand gene expression in human CD4+ T cells.

Ghare SS, Joshi-Barve S, Moghe A, Patil M, Barker DF, Gobejishvili L, Brock GN, Cave M, McClain CJ, Barve SS.

J Immunol. 2014 Jul 1;193(1):412-21. doi: 10.4049/jimmunol.1400055. Epub 2014 Jun 4. PMID: 24899502.

Chronic binge alcohol consumption alters myogenic gene expression and reduces in vitro myogenic differentiation potential of myoblasts from rhesus macaques.

Simon L, LeCapitaine N, Berner P, Vande Stouwe C, Mussell JC, Allerton T, Primeaux SD, Dufour J, Nelson S, Bagby GJ, Cefalu W, Molina PE.

Am J Physiol Regul Integr Comp Physiol. 2014 Jun 1;306(11):R837-44. doi: 10.1152/ajpregu.00502.2013. Epub 2014 Mar 26. PMID: 24671243.

Alcohol abuse: critical pathophysiological processes and contribution to disease burden.

Molina PE, Gardner JD, Souza-Smith FM, Whitaker AM.

Physiology (Bethesda). 2014 May;29(3):203-15. doi: 10.1152/physiol.00055.2013. PMID: 24789985.

The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice.

Deshmukh HS, Liu Y, Menkiti OR, Mei J, Dai N, O'Leary CE, Oliver PM, Kolls JK, Weiser JN, Worthen GS.

Nat Med. 2014 May;20(5):524-30. doi: 10.1038/nm.3542. Epub 2014 Apr 20. PMID: 24747744.

Acute alcohol intoxication impairs methicillin-resistant Staphylococcus aureus clearance in the lung by impeding epithelial production of Reg3γ.

Choi SM, McAleer JP, Trevejo-Nunez G, Pociask DA, Armentrout RA, Chen K, Kolls JK.

Infect Immun. 2014 Apr;82(4):1402-7. doi: 10.1128/IAI.00974-13. Epub 2014 Jan 13. PMID: 24421048.

Cigarette Smoke Alters the Hematopoietic Stem Cell Niche.

Siggins RW, Hossain F, Rehman T, Melvan JN, Zhang P, Welsh DA.

Med Sci (Basel). 2014 Mar;2(1):37-50. doi: 10.3390/medsci2010037. Epub 2014 Feb 18. PMID: 28868162.

Alcohol modulation of cardiac matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs favors collagen accumulation.

El Hajj EC, El Hajj MC, Voloshenyuk TG, Mouton AJ, Khoutorova E, Molina PE, Gilpin NW, Gardner JD.

Alcohol Clin Exp Res. 2014 Feb;38(2):448-56. doi: 10.1111/acer.12239. Epub 2013 Aug 19. PMID: 24033327.

Chronic alcohol abuse and HIV disease progression: studies with the non-human primate model.

Amedee AM, Nichols WA, Robichaux S, Bagby GJ, Nelson S.

Curr HIV Res. 2014;12(4):243-53. doi: 10.2174/1570162x12666140721115717. PMID: 25053367.

Biomedical consequences of alcohol use disorders in the HIV-infected host.

Molina PE, Bagby GJ, Nelson S.

Curr HIV Res. 2014;12(4):265-75. doi: 10.2174/1570162x12666140721121849. PMID: 25053365.

Alcohol binging exacerbates adipose tissue inflammation following burn injury.

Molina PE.

Alcohol Clin Exp Res. 2014 Jan;38(1):33-5. doi: 10.1111/acer.12296. Epub 2013 Oct 31. PMID: 24175882.

Dysregulation in lung immunity - the protective and pathologic Th17 response in infection.

Way EE, Chen K, Kolls JK.

Eur J Immunol. 2013 Dec;43(12):3116-24. doi: 10.1002/eji.201343713. Epub 2013 Oct 16. PMID: 24130019.

Effects of alcohol consumption on antigen-specific cellular and humoral immune responses to SIV in rhesus macaques.

Pahar B, Amedee AM, Thomas J, Dufour JP, Zhang P, Nelson S, Veazey RS, Bagby GJ.

J Acquir Immune Defic Syndr. 2013 Dec 1;64(4):332-41. doi: 10.1097/QAI.0b013e31829f6dca. PMID: 23799411.

Accessibility and effectiveness of sources of information about HIV/AIDS in a rural population.

Hormes JM, Theall KP.

South Med J. 2013 Nov;106(11):599-604. doi: 10.1097/SMJ.0000000000000011. PMID: 24192588.

Chronic alcohol induces M2 polarization enhancing pulmonary disease caused by exposure to particulate air pollution.

Thevenot P, Saravia J, Giaimo J, Happel KI, Dugas TR, Cormier SA.

Alcohol Clin Exp Res. 2013 Nov;37(11):1910-9. doi: 10.1111/acer.12184. Epub 2013 Jun 13. PMID: 23763452.

Response of Differentiated Human Airway Epithelia to Alcohol Exposure and Klebsiella Pneumoniae Challenge.

Raju SV, Painter RG, Bagby GJ, Nelson S, Wang G.

Med Sci (Basel). 2013 Jul 26;1(1):2-19. doi: 10.3390/medsci1010002. PMID: 25485141.

Effect of bacterial pneumonia on lung simian immunodeficiency virus (SIV) replication in alcohol consuming SIV-infected rhesus macaques.

Nelson S, Happel KI, Zhang P, Myers L, Dufour JP, Bagby GJ.

Alcohol Clin Exp Res. 2013 Jun;37(6):969-77. doi: 10.1111/acer.12070. Epub 2013 Feb 15. PMID: 23414480.

Cerebrospinal fluid miRNA profile in HIV-encephalitis.

Pacifici M, Delbue S, Ferrante P, Jeansonne D, Kadri F, Nelson S, Velasco-Gonzalez C, Zabaleta J, Peruzzi F.

J Cell Physiol. 2013 May;228(5):1070-5. doi: 10.1002/jcp.24254. PMID: 23042033.

Impact of altered methylation in cytokine signaling and proteasome function in alcohol and viral-mediated diseases.

Kharbanda KK, Bardag-Gorce F, Barve S, Molina PE, Osna NA.

Alcohol Clin Exp Res. 2013 Jan;37(1):1-7. doi: 10.1111/j.1530-0277.2012.01840.x. Epub 2012 May 11. PMID: 22577887.

Cumulative neighborhood risk of psychosocial stress and allostatic load in adolescents.

Theall KP, Drury SS, Shirtcliff EA.

Am J Epidemiol. 2012 Oct 1;176 Suppl 7(Suppl 7):S164-74. doi: 10.1093/aje/kws185. PMID: 23035140.

Multilevel spatiotemporal change-point models for evaluating the effect of an alcohol outlet control policy on changes in neighborhood assaultive violence rates.

Xu Y, Yu Q, Scribner R, Theall K, Scribner S, Simonsen N.

Spat Spatiotemporal Epidemiol. 2012 Jun;3(2):121-8. doi: 10.1016/j.sste.2012.04.005. Epub 2012 Apr 21. PMID: 22682438.

Alcohol impairs the myeloid proliferative response to bacteremia in mice by inhibiting the stem cell antigen-1/ERK pathway.

Melvan JN, Siggins RW, Stanford WL, Porretta C, Nelson S, Bagby GJ, Zhang P.

J Immunol. 2012 Feb 15;188(4):1961-9. doi: 10.4049/jimmunol.1102395. Epub 2012 Jan 11. PMID: 22238460.

Disrupted anabolic and catabolic processes may contribute to alcohol-accentuated SAIDS-associated wasting.

LeCapitaine NJ, Wang ZQ, Dufour JP, Potter BJ, Bagby GJ, Nelson S, Cefalu WT, Molina PE.

J Infect Dis. 2011 Oct 15;204(8):1246-55. doi: 10.1093/infdis/jir508. PMID: 21917898.

Effects of pregnanolone and flunitrazepam on the retention of response sequences in rats.

Amato RJ, Moerschbaecher JM, Winsauer PJ.

Pharmacol Biochem Behav. 2011 Sep;99(3):391-8. doi: 10.1016/j.pbb.2011.05.023. Epub 2011 May 27. PMID: 21640749.

Suppression of the stem cell antigen-1 response and granulocyte lineage expansion by alcohol during septicemia.

Melvan JN, Siggins RW, Bagby GJ, Stanford WL, Welsh DA, Nelson S, Zhang P.

Crit Care Med. 2011 Sep;39(9):2121-30. doi: 10.1097/CCM.0b013e31821e89dc. PMID: 21602669.

Impact of small group size on neighbourhood influences in multilevel models.

Theall KP, Scribner R, Broyles S, Yu Q, Chotalia J, Simonsen N, Schonlau M, Carlin BP.

J Epidemiol Community Health. 2011 Aug;65(8):688-95. doi: 10.1136/jech.2009.097956. Epub 2010 May 27. PMID: 20508007.

Impaired expansion and multipotentiality of adult stromal cells in a rat chronic alcohol abuse model.

Huff NK, Spencer ND, Gimble JM, Bagby GJ, Nelson S, Lopez MJ.

Alcohol. 2011 Jun;45(4):393-402. doi: 10.1016/j.alcohol.2010.12.005. Epub 2011 Mar 4. PMID: 21376503.

Effects of 7-keto dehydroepiandrosterone on voluntary ethanol intake in male rats.

Worrel ME, Gurkovskaya OV, Leonard ST, Lewis PB, Winsauer PJ.

Alcohol. 2011 Jun;45(4):349-54. doi: 10.1016/j.alcohol.2010.08.020. Epub 2010 Nov 4. PMID: 21051179.

The neighborhood alcohol environment and at-risk drinking among African-Americans.

Theall KP, Lancaster BP, Lynch S, Haines RT, Scribner S, Scribner R, Kishore V.

Alcohol Clin Exp Res. 2011 May;35(5):996-1003. doi: 10.1111/j.1530-0277.2010.01430.x. Epub 2011 Feb 15. PMID: 21323681.

Alcohol suppresses the granulopoietic response to pulmonary Streptococcus pneumoniae infection with enhancement of STAT3 signaling.

Siggins RW, Melvan JN, Welsh DA, Bagby GJ, Nelson S, Zhang P.

J Immunol. 2011 Apr 1;186(7):4306-13. doi: 10.4049/jimmunol.1002885. Epub 2011 Feb 28. PMID: 21357267.

Alcohol prevention on college campuses: the moderating effect of the alcohol environment on the effectiveness of social norms marketing campaigns.

Scribner RA, Theall KP, Mason K, Simonsen N, Schneider SK, Towvim LG, DeJong W.

J Stud Alcohol Drugs. 2011 Mar;72(2):232-9. doi: 10.15288/jsad.2011.72.232. PMID: 21388596.

Neurosteroid Binding Sites on the GABA(A) Receptor Complex as Novel Targets for Therapeutics to Reduce Alcohol Abuse and Dependence.

Hulin MW, Amato RJ, Porter JR, Filipeanu CM, Winsauer PJ.

Adv Pharmacol Sci. 2011;2011:926361. doi: 10.1155/2011/926361. Epub 2011 Oct 31. PMID: 22110489.

Alcohol and HIV Infection.

Nelson S, Bagby GJ.

Trans Am Clin Climatol Assoc. 2011;122:244-53. PMID: 21686230.

Effects of positive and negative modulators of the γ-aminobutyric acid A receptor complex on responding under a differential-reinforcement-of-low-rate schedule of reinforcement in rats.

Amato RJ, Lewis PB, He H, Winsauer PJ.

Behav Pharmacol. 2010 Dec;21(8):727-35. doi: 10.1097/FBP.0b013e32833fa7c7. PMID: 20838210.

Acute alcohol intoxication impairs the hematopoietic precursor cell response to pneumococcal pneumonia.

Raasch CE, Zhang P, Siggins RW 2nd, LaMotte LR, Nelson S, Bagby GJ.

Alcohol Clin Exp Res. 2010 Dec;34(12):2035-43. doi: 10.1111/j.1530-0277.2010.01291.x. PMID: 20659065.

Characterization of SIV in the oral cavity and in vitro inhibition of SIV by rhesus macaque saliva.

Thomas JS, Lacour N, Kozlowski PA, Nelson S, Bagby GJ, Amedee AM.

AIDS Res Hum Retroviruses. 2010 Aug;26(8):901-11. doi: 10.1089/aid.2009.0235. PMID: 20672998.

Neonatal sepsis and neutrophil insufficiencies.

Melvan JN, Bagby GJ, Welsh DA, Nelson S, Zhang P.

Int Rev Immunol. 2010 Jun;29(3):315-48. doi: 10.3109/08830181003792803. PMID: 20521927.

Ethanol upregulates glucocorticoid-induced leucine zipper expression and modulates cellular inflammatory responses in lung epithelial cells.

Gomez M, Raju SV, Viswanathan A, Painter RG, Bonvillain R, Byrne P, Nguyen DH, Bagby GJ, Kolls JK, Nelson S, Wang G.

J Immunol. 2010 May 15;184(10):5715-22. doi: 10.4049/jimmunol.0903521. Epub 2010 Apr 9. PMID: 20382889.

An ecological analysis of alcohol-outlet density and campus-reported violence at 32 U.S. colleges.

Scribner RA, Mason KE, Simonsen NR, Theall K, Chotalia J, Johnson S, Schneider SK, DeJong W.

J Stud Alcohol Drugs. 2010 Mar;71(2):184-91. doi: 10.15288/jsad.2010.71.184. PMID: 20230715.

Gonadal hormones modulate the potency of the disruptive effects of donepezil in male rats responding under a nonspatial operant learning and performance task.

Leonard ST, Hearn JK, Catling AD, Winsauer PJ.

Behav Pharmacol. 2010 Mar;21(2):121-34. doi: 10.1097/FBP.0b013e328337be3a. PMID: 20177375.

Alcohol's role in HIV transmission and disease progression.

Pandrea I, Happel KI, Amedee AM, Bagby GJ, Nelson S.

Alcohol Res Health. 2010;33(3):203-18. PMID: 23584062.

Focus on: Alcohol and the immune system.

Molina PE, Happel KI, Zhang P, Kolls JK, Nelson S.

Alcohol Res Health. 2010;33(1-2):97-108. PMID: 23579940.

Misspecification of the effect of race in fixed effects models of health inequalities.

Scribner RA, Theall KP, Simonsen NR, Mason KE, Yu Q.

Soc Sci Med. 2009 Dec;69(11):1584-91. doi: 10.1016/j.socscimed.2009.08.010. Epub 2009 Oct 1. PMID: 19800158.

Efficient methodologies for sensitive HIV-1 RNA quantitation from plasma and vaginal secretions.

Henning TR, Lacour N, Amedee AM.

J Clin Virol. 2009 Dec;46(4):309-13. doi: 10.1016/j.jcv.2009.08.015. Epub 2009 Sep 23. PMID: 19783472.

Neutrophil-mediated lung permeability and host defense proteins.

Kantrow SP, Shen Z, Jagneaux T, Zhang P, Nelson S.

Am J Physiol Lung Cell Mol Physiol. 2009 Oct;297(4):L738-45. doi: 10.1152/ajplung.00045.2009. Epub 2009 Jul 31. PMID: 19648288.

The neighborhood alcohol environment and alcohol-related morbidity.

Theall KP, Scribner R, Cohen D, Bluthenthal RN, Schonlau M, Lynch S, Farley TA.

Alcohol Alcohol. 2009 Sep-Oct;44(5):491-9. doi: 10.1093/alcalc/agp042. Epub 2009 Aug 10. PMID: 19671569.

Alcohol exposure impairs myeloid dendritic cell function in rhesus macaques.

Siggins RW, Bagby GJ, Molina P, Dufour J, Nelson S, Zhang P.

Alcohol Clin Exp Res. 2009 Sep;33(9):1524-31. doi: 10.1111/j.1530-0277.2009.00980.x. Epub 2009 May 26. PMID: 19485975.

Association of FAK activation with lentivirus-induced disruption of blood-brain barrier tight junction-associated ZO-1 protein organization.

Ivey NS, Renner NA, Moroney-Rasmussen T, Mohan M, Redmann RK, Didier PJ, Alvarez X, Lackner AA, MacLean AG.

J Neurovirol. 2009 Jul;15(4):312-23. doi: 10.1080/13550280902998413. PMID: 19521898.

Discriminative stimulus effects of ethanol, pregnanolone, and dehydroepiandrosterone (DHEA) in rats administered ethanol or saline as adolescents.

Gurkovskaya OV, Winsauer PJ.

Pharmacol Biochem Behav. 2009 Jul;93(1):82-90. doi: 10.1016/j.pbb.2009.04.012. Epub 2009 Apr 23. PMID: 19393687.

Effects of pregnanolone and dehydroepiandrosterone on ethanol intake in rats administered ethanol or saline during adolescence.

Gurkovskaya OV, Leonard ST, Lewis PB, Winsauer PJ.

Alcohol Clin Exp Res. 2009 Jul;33(7):1252-64. doi: 10.1111/j.1530-0277.2009.00951.x. Epub 2009 Apr 21. PMID: 19389187.

Alcohol and trauma: a summary of the Satellite Symposium at the 30th Annual Meeting of the Shock Society.

Bird MD, Choudhry MA, Molina PE, Kovacs EJ.

Alcohol. 2009 May;43(3):247-52. doi: 10.1016/j.alcohol.2008.12.006. PMID: 19393863.

Relative potency and effectiveness of flunitrazepam, ethanol, and beta-CCE for disrupting the acquisition and retention of response sequences in rats.

Leonard ST, Gerak LR, Delatte MS, Moerschbaecher JM, Winsauer PJ.

Behav Pharmacol. 2009 Feb;20(1):33-44. doi: 10.1097/FBP.0b013e3283242f2d. PMID: 19179849.

Acute alcohol intoxication inhibits the lineage- c-kit+ Sca-1+ cell response to Escherichia coli bacteremia.

Zhang P, Welsh DA, Siggins RW 2nd, Bagby GJ, Raasch CE, Happel KI, Nelson S.

J Immunol. 2009 Feb 1;182(3):1568-76. doi: 10.4049/jimmunol.182.3.1568. PMID: 19155505.

Ethanol exposure impairs LPS-induced pulmonary LIX expression: alveolar epithelial cell dysfunction as a consequence of acute intoxication.

Walker JE Jr, Odden AR, Jeyaseelan S, Zhang P, Bagby GJ, Nelson S, Happel KI.

Alcohol Clin Exp Res. 2009 Feb;33(2):357-65. doi: 10.1111/j.1530-0277.2008.00844.x. Epub 2008 Nov 25. PMID: 19053978.

The systemic and pulmonary LPS binding protein response to intratracheal lipopolysaccharide.

Gamble L, Bagby GJ, Quinton LJ, Happel KI, Mizgerd JP, Zhang P, Nelson S.

Shock. 2009 Feb;31(2):212-7. doi: 10.1097/SHK.0b013e31817c0d7d. PMID: 18520704.

Estradiol replacement in gonadectomized male rats alters scopolamine-induced disruptions of nonspatial learning.

Leonard ST, Moerschbaecher JM, Winsauer PJ.

Exp Clin Psychopharmacol. 2008 Dec;16(6):532-46. doi: 10.1037/a0013718. PMID: 19086774.

Resource loss, coping, alcohol use, and posttraumatic stress symptoms among survivors of Hurricane Katrina: a cross-sectional study.

Kishore V, Theall KP, Robinson W, Pichon J, Scribner R, Roberson E, Johnson S.

Am J Disaster Med. 2008 Nov-Dec;3(6):345-57. PMID: 19202888.

Importance of TLR2 in early innate immune response to acute pulmonary infection with Porphyromonas gingivalis in mice.

Hajishengallis G, Wang M, Bagby GJ, Nelson S.

J Immunol. 2008 Sep 15;181(6):4141-9. doi: 10.4049/jimmunol.181.6.4141. PMID: 18768871.

The lineage-c-Kit+Sca-1+ cell response to Escherichia coli bacteremia in Balb/c mice.

Zhang P, Nelson S, Bagby GJ, Siggins R 2nd, Shellito JE, Welsh DA.

Stem Cells. 2008 Jul;26(7):1778-86. doi: 10.1634/stemcells.2007-1027. Epub 2008 May 15. PMID: 18483422.

Alcohol consumption and HIV-1 vaginal RNA shedding among women.

Theall KP, Amedee A, Clark RA, Dumestre J, Kissinger P.

J Stud Alcohol Drugs. 2008 May;69(3):454-8. doi: 10.15288/jsad.2008.69.454. PMID: 18432389.

Overlapping, but not identical, discriminative stimulus effects of the neuroactive steroid pregnanolone and ethanol.

Gerak LR, Moerschbaecher JM, Winsauer PJ.

Pharmacol Biochem Behav. 2008 May;89(3):473-9. doi: 10.1016/j.pbb.2008.02.005. Epub 2008 Feb 11. PMID: 18328551.

Alcohol abuse, immunosuppression, and pulmonary infection.

Zhang P, Bagby GJ, Happel KI, Raasch CE, Nelson S.

Curr Drug Abuse Rev. 2008 Jan;1(1):56-67. doi: 10.2174/1874473710801010056. PMID: 19630706.

Stem cells, phenotypic inversion, and differentiation.

Siggins RW, Zhang P, Welsh D, Lecapitaine NJ, Nelson S.

Int J Clin Exp Med. 2008;1(1):2-21. Epub 2008 Jan 20. PMID: 19079683.

Chronic alcohol accentuates simian acquired immunodeficiency syndrome-associated wasting.

Molina PE, Lang CH, McNurlan M, Bagby GJ, Nelson S.

Alcohol Clin Exp Res. 2008 Jan;32(1):138-47. doi: 10.1111/j.1530-0277.2007.00549.x. Epub 2007 Nov 20. PMID: 18028526.

Complications of gastric catheters implanted in rhesus macaques (Macaca mulatta).

Dufour J, Ooms TG, Phillippi-Falkenstein KM, Penney T, Doyle L, Bagby GJ, Nelson S, Veazey RS, Bohm RP Jr.

J Am Assoc Lab Anim Sci. 2007 Nov;46(6):29-34. PMID: 17994670.

Acute alcohol intoxication suppresses the pulmonary ELR-negative CXC chemokine response to lipopolysaccharide.

Happel KI, Rudner X, Quinton LJ, Movassaghi JL, Clark C, Odden AR, Zhang P, Bagby GJ, Nelson S, Shellito JE.

Alcohol. 2007 Aug;41(5):325-33. doi: 10.1016/j.alcohol.2007.06.002. PMID: 17889309.

CD4+ CD25+ transforming growth factor-beta-producing T cells are present in the lung in murine tuberculosis and may regulate the host inflammatory response.

Mason CM, Porretta E, Zhang P, Nelson S.

Clin Exp Immunol. 2007 Jun;148(3):537-45. doi: 10.1111/j.1365-2249.2007.03371.x. Epub 2007 Mar 16. PMID: 17362490.

Alcohol binge before trauma/hemorrhage impairs integrity of host defense mechanisms during recovery.

Greiffenstein P, Mathis KW, Stouwe CV, Molina PE.

Alcohol Clin Exp Res. 2007 Apr;31(4):704-15. doi: 10.1111/j.1530-0277.2007.00355.x. PMID: 17374050.

Testosterone potentiates scopolamine-induced disruptions of nonspatial learning in gonadectomized male rats.

Leonard ST, Moerschbaecher JM, Winsauer PJ.

Exp Clin Psychopharmacol. 2007 Feb;15(1):48-57. doi: 10.1037/1064-1297.15.1.48. PMID: 17295584.

Alcohol intoxication inhibits pulmonary S100A8 and S100A9 expression in rats challenged with intratracheal lipopolysaccharide.

Zhang P, Zhong Q, Bagby GJ, Nelson S.

Alcohol Clin Exp Res. 2007 Jan;31(1):113-21. doi: 10.1111/j.1530-0277.2006.00269.x. PMID: 17207109.

Effects of gamma-hydroxybutyric acid and flunitrazepam on ethanol intake in male rats.

Leonard ST, Gerak LR, Gurkovskaya O, Moerschbaecher JM, Winsauer PJ.

Pharmacol Biochem Behav. 2006 Dec;85(4):780-6. doi: 10.1016/j.pbb.2006.11.013. Epub 2007 Jan 8. PMID: 17208286.

Chronic alcohol accentuates nutritional, metabolic, and immune alterations during asymptomatic simian immunodeficiency virus infection.

Molina PE, McNurlan M, Rathmacher J, Lang CH, Zambell KL, Purcell J, Bohm RP, Zhang P, Bagby GJ, Nelson S.

Alcohol Clin Exp Res. 2006 Dec;30(12):2065-78. doi: 10.1111/j.1530-0277.2006.00252.x. PMID: 17117972.

Effects of pregnanolone in rats discriminating cocaine.

Quinton MS, Gerak LR, Moerschbaecher JM, Winsauer PJ.

Pharmacol Biochem Behav. 2006 Oct;85(2):385-92. doi: 10.1016/j.pbb.2006.09.006. Epub 2006 Oct 18. PMID: 17055039.

Chronic binge ethanol consumption accelerates progression of simian immunodeficiency virus disease.

Bagby GJ, Zhang P, Purcell JE, Didier PJ, Nelson S.

Alcohol Clin Exp Res. 2006 Oct;30(10):1781-90. doi: 10.1111/j.1530-0277.2006.00211.x. PMID: 17010145.

Acute alcohol intoxication suppresses the interleukin 23 response to Klebsiella pneumoniae infection.

Happel KI, Odden AR, Zhang P, Shellito JE, Bagby GJ, Nelson S.

Alcohol Clin Exp Res. 2006 Jul;30(7):1200-7. doi: 10.1111/j.1530-0277.2006.00144.x. PMID: 16792568.

Experimental infection of rhesus macaques with Streptococcus pneumoniae: a possible model for vaccine assessment.

Philipp MT, Purcell JE, Martin DS, Buck WR, Plauché GB, Ribka EP, DeNoel P, Hermand P, Leiva LE, Bagby GJ, Nelson S.

J Med Primatol. 2006 Jun;35(3):113-22. doi: 10.1111/j.1600-0684.2006.00164.x. PMID: 16764668.

Intestinal lymphocyte subsets and turnover are affected by chronic alcohol consumption: implications for SIV/HIV infection.

Poonia B, Nelson S, Bagby GJ, Veazey RS.

J Acquir Immune Defic Syndr. 2006 Apr 15;41(5):537-47. doi: 10.1097/ PMID: 16652027.

Alcohol reversibly disrupts TNF-alpha/TACE interactions in the cell membrane.

Song K, Zhao XJ, Marrero L, Oliver P, Nelson S, Kolls JK.

Respir Res. 2005 Oct 24;6(1):123. doi: 10.1186/1465-9921-6-123. PMID: 16246259.

Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae.

Happel KI, Dubin PJ, Zheng M, Ghilardi N, Lockhart C, Quinton LJ, Odden AR, Shellito JE, Bagby GJ, Nelson S, Kolls JK.

J Exp Med. 2005 Sep 19;202(6):761-9. doi: 10.1084/jem.20050193. Epub 2005 Sep 12. PMID: 16157683.

Effects of systemic and local CXC chemokine administration on the ethanol-induced suppression of pulmonary neutrophil recruitment.

Quinton LJ, Nelson S, Zhang P, Happel KI, Gamble L, Bagby GJ.

Alcohol Clin Exp Res. 2005 Jul;29(7):1198-205. doi: 10.1097/01.alc.0000171927.66130.aa. PMID: 16046875.

The granulopoietic cytokine response and enhancement of granulopoiesis in mice during endotoxemia.

Zhang P, Quinton LJ, Gamble L, Bagby GJ, Summer WR, Nelson S.

Shock. 2005 Apr;23(4):344-52. doi: 10.1097/ PMID: 15803058.

Pulmonary host defenses and factors predisposing to lung infection.

Mason CM, Nelson S.

Clin Chest Med. 2005 Mar;26(1):11-7. doi: 10.1016/j.ccm.2004.10.018. PMID: 15802161.

Interaction between 1,4-butanediol and ethanol on operant responding and the cardiovascular system.

Gerak LR, Hicks AR, Winsauer PJ, Varner KJ.

Eur J Pharmacol. 2004 Dec 3;506(1):75-82. doi: 10.1016/j.ejphar.2004.10.044. PMID: 15588627.

Chronic ethanol enhances ectodomain shedding in T cells and monocytes.

Zhao XJ, Oliver P, Song K, Schurr J, Zhang Z, Kolls JK.

Alcohol Clin Exp Res. 2004 Sep;28(9):1399-407. doi: 10.1097/01.alc.0000139819.46514.06. PMID: 15365312.

Escherichia coli pneumonia enhances granulopoiesis and the mobilization of myeloid progenitor cells into the systemic circulation.

Shahbazian LM, Quinton LJ, Bagby GJ, Nelson S, Wang G, Zhang P.

Crit Care Med. 2004 Aug;32(8):1740-6. doi: 10.1097/01.ccm.0000132900.84627.90. PMID: 15286552.

Selective transport of cytokine-induced neutrophil chemoattractant from the lung to the blood facilitates pulmonary neutrophil recruitment.

Quinton LJ, Nelson S, Zhang P, Boé DM, Happel KI, Pan W, Bagby GJ.

Am J Physiol Lung Cell Mol Physiol. 2004 Mar;286(3):L465-72. doi: 10.1152/ajplung.00153.2003. Epub 2003 Nov 14. PMID: 14617513.

Immune response modulation in acutely ethanol-intoxicated, acutely diabetic male and female rats.

Olubadewo JO, Spitzer JA.

Alcohol. 2003 Nov;31(3):137-47. doi: 10.1016/j.alcohol.2003.09.004. PMID: 14693262.

Alcohol-induced suppression of lung chemokine production and the host defense response to Streptococcus pneumoniae.

Boé DM, Nelson S, Zhang P, Quinton L, Bagby GJ.

Alcohol Clin Exp Res. 2003 Nov;27(11):1838-45. doi: 10.1097/01.ALC.0000095634.82310.53. PMID: 14634502.

Effects of the delta-opioid receptor agonist SNC80 on learning relative to its antidepressant-like effects in rats.

Jutkiewicz EM, Rice KC, Woods JH, Winsauer PJ.

Behav Pharmacol. 2003 Nov;14(7):509-16. doi: 10.1097/00008877-200311000-00003. PMID: 14557718.

Contingent and noncontingent cocaine administration in rhesus monkeys: a comparison of the effects on the acquisition and performance of response sequences.

Winsauer PJ, Moerschbaecher JM, Molina PE, Roussell AM.

Behav Pharmacol. 2003 Jul;14(4):295-306. doi: 10.1097/01.fbp.0000081785.35927.08. PMID: 12838035.

Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection.

Happel KI, Zheng M, Young E, Quinton LJ, Lockhart E, Ramsay AJ, Shellito JE, Schurr JR, Bagby GJ, Nelson S, Kolls JK.

J Immunol. 2003 May 1;170(9):4432-6. doi: 10.4049/jimmunol.170.9.4432. PMID: 12707317.

Acute alcohol inhibits TNF-alpha processing in human monocytes by inhibiting TNF/TNF-alpha-converting enzyme interactions in the cell membrane.

Zhao XJ, Marrero L, Song K, Oliver P, Chin SY, Simon H, Schurr JR, Zhang Z, Thoppil D, Lee S, Nelson S, Kolls JK.

J Immunol. 2003 Mar 15;170(6):2923-31. doi: 10.4049/jimmunol.170.6.2923. PMID: 12626543.

Mechanisms of alcohol-induced tissue injury.

Molina PE, Hoek JB, Nelson S, Guidot DM, Lang CH, Wands JR, Crawford JM.

Alcohol Clin Exp Res. 2003 Mar;27(3):563-75. doi: 10.1097/01.ALC.0000057946.57330.F7. PMID: 12658123.

The effect of chronic binge ethanol consumption on the primary stage of SIV infection in rhesus macaques.

Bagby GJ, Stoltz DA, Zhang P, Kolls JK, Brown J, Bohm RP Jr, Rockar R, Purcell J, Murphey-Corb M, Nelson S.

Alcohol Clin Exp Res. 2003 Mar;27(3):495-502. doi: 10.1097/01.ALC.0000057947.57330.BE. PMID: 12658116.

Interferon-gamma enhances the pulmonary CXC chemokine response to intratracheal lipopolysaccharide challenge.

Zhang P, Quinton LJ, Bagby GJ, Summer WR, Nelson S.

J Infect Dis. 2003 Jan 1;187(1):62-9. doi: 10.1086/346027. Epub 2002 Dec 13. PMID: 12508147.

Modulation of immunity and viral-host interactions by alcohol.

Thiele GM, Szabo G, Kovacs EJ, Bautista AP, Sosa L, Jerrells TR.

Alcohol Clin Exp Res. 2002 Dec;26(12):1897-908. PMID: 12500115.

Alcohol unmasks simian immunodeficiency virus-induced cognitive impairments in rhesus monkeys.

Winsauer PJ, Moerschbaecher JM, Brauner IN, Purcell JE, Lancaster JR Jr, Bagby GJ, Nelson S.

Alcohol Clin Exp Res. 2002 Dec;26(12):1846-57. doi: 10.1097/01.ALC.0000042171.80435.F1. PMID: 12500109.

Neutrophil modulation of the pulmonary chemokine response to lipopolysaccharide.

Holmes MC, Zhang P, Nelson S, Summer WR, Bagby GJ.

Shock. 2002 Dec;18(6):555-60. doi: 10.1097/00024382-200212000-00012. PMID: 12462565.

Sex differences in the modulation by ethanol of lung chemotaxis.

Spitzer JA, Zhang P, Bagby GJ, Stouwe CV, Nelson S.

Alcohol. 2002 Oct;28(2):95-102. doi: 10.1016/s0741-8329(02)00271-9. PMID: 12457940.

Hepatitis C virus (HCV) and human immunodeficiency virus type 1 (HIV-1) infections in alcoholics.

Prakash O, Mason A, Luftig RB, Bautista AP.

Front Biosci. 2002 Jul 1;7:e286-300. doi: 10.2741/A924. Epub 2002 Jul 1. PMID: 12086918.

Acute ethanol administration downregulates human immunodeficiency virus-1 glycoprotein 120-induced KC and RANTES production by murine Kupffer cells and splenocytes.

Bautista AP, Wang E.

Life Sci. 2002 Jun 14;71(4):371-82. doi: 10.1016/s0024-3205(02)01687-9. PMID: 12044837.

9-[(Hydroxymethyl)phenyl]adenines: new aryladenine substrates of adenosine deaminase.

Brakta M, Murthy D, Ellis L, Phadtare S.

Bioorg Med Chem Lett. 2002 Jun 3;12(11):1489-92. doi: 10.1016/s0960-894x(02)00192-0. PMID: 12031326.

Chronic alcohol intoxication primes Kupffer cells and endothelial cells for enhanced CC-chemokine production and concomitantly suppresses phagocytosis and chemotaxis.

Bautista AP.

Front Biosci. 2002 Jun 1;7:a117-25. doi: 10.2741/a746. PMID: 12045006.

Neutrophilic infiltration in alcoholic hepatitis.

Bautista AP.

Alcohol. 2002 May;27(1):17-21. doi: 10.1016/s0741-8329(02)00206-9. PMID: 12062632.

Ethanol and LPS modulate NF-kappaB activation, inducible NO synthase and COX-2 gene expression in rat liver cells in vivo.

Spitzer JA, Zheng M, Kolls JK, Vande Stouwe C, Spitzer JJ.

Front Biosci. 2002 May 1;7:a99-108. doi: 10.2741/A744. PMID: 11994208.

Pulmonary host defenses and alcohol.

Zhang P, Bagby GJ, Happel KI, Summer WR, Nelson S.

Front Biosci. 2002 May 1;7:d1314-30. doi: 10.2741/A842. PMID: 11991862.

Effects of in vitro ethanol on tumor necrosis factor-alpha production by blood obtained from simian immunodeficiency virus-infected rhesus macaques.

Stoltz DA, Nelson S, Kolls JK, Zhang P, Bohm RP, Murphey-Corb M, Bagby GJ.

Alcohol Clin Exp Res. 2002 Apr;26(4):527-34. PMID: 11981130.

Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line.

Prakash O, Tang ZY, Zhou P, Peng X, Kolls J, Shellito JE, Nelson S.

Alcohol Clin Exp Res. 2002 Mar;26(3):295-302. PMID: 11923581.

Compartmentalization of macrophage inflammatory protein-2, but not cytokine-induced neutrophil chemoattractant, in rats challenged with intratracheal endotoxin.

Zhang P, Nelson S, Holmes MC, Summer WR, Bagby GJ.

Shock. 2002 Feb;17(2):104-8. doi: 10.1097/00024382-200202000-00004. PMID: 11837784.

Molecular pathology and clinical aspects of alcohol-induced tissue injury.

Molina PE, McClain C, Valla D, Guidot D, Diehl AM, Lang CH, Neuman M.

Alcohol Clin Exp Res. 2002 Jan;26(1):120-8. PMID: 11821662.

Acute alcohol intoxication suppresses the CXC chemokine response during endotoxemia.

Zhang P, Bagby GJ, Boé DM, Zhong Q, Schwarzenberger P, Kolls JK, Summer WR, Nelson S.

Alcohol Clin Exp Res. 2002 Jan;26(1):65-73. PMID: 11821656.

Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule-deficient mice.

Forlow SB, Schurr JR, Kolls JK, Bagby GJ, Schwarzenberger PO, Ley K.

Blood. 2001 Dec 1;98(12):3309-14. doi: 10.1182/blood.v98.12.3309. PMID: 11719368.

Chronic ethanol intoxication enhances the production of cytokine-induced neutrophil chemoattractant and macrophage inflammatory protein-2 by hepatocytes after human immunodeficiency virus-1 glycoprotein 120 vaccination.

Bautista AP, Wang E.

Alcohol. 2001 May;24(1):35-44. doi: 10.1016/s0741-8329(01)00140-9. PMID: 11524180.

Acute alcohol intoxication and endotoxemia desensitize HIV-1 gp120-induced CC-chemokine production by Kupffer cells.

Bautista AP.

Life Sci. 2001 Mar 16;68(17):1939-49. doi: 10.1016/s0024-3205(01)00986-9. PMID: 11388697.

Cytokine treatment of bacterial pneumonia.

Nelson S, Bagby GJ, Dale D.

Semin Respir Infect. 2001 Mar;16(1):38-46. doi: 10.1053/srin.2001.22727. PMID: 11309711.

Inhibition of hematopoietic progenitor cell proliferation by ethanol in human immunodeficiency virus type 1 tat-expressing transgenic mice.

Prakash O, Rodriguez VE, Tang ZY, Zhou P, Coleman R, Dhillon G, Shellito JE, Nelson S.

Alcohol Clin Exp Res. 2001 Mar;25(3):450-6. PMID: 11290858.

Use of rat models to mimic alterations in iron homeostasis during human alcohol abuse and cirrhosis.

Gentry-Nielsen MJ, Preheim LC, Lyman KN, McDonough KH, Potter BJ.

Alcohol. 2001 Feb;23(2):71-81. doi: 10.1016/s0741-8329(00)00130-0. PMID: 11331104.

Effects of endotoxin on neutrophil-mediated I/R injury in isolated perfused rat hearts.

Lipton BP, Bautista AP, Delcarpio JB, McDonough KH.

Am J Physiol Heart Circ Physiol. 2001 Feb;280(2):H802-11. doi: 10.1152/ajpheart.2001.280.2.H802. PMID: 11158980.

The effects of granulocyte colony-stimulating factor and neutrophil recruitment on the pulmonary chemokine response to intratracheal endotoxin.

Zhang P, Bagby GJ, Kolls JK, Welsh DA, Summer WR, Andresen J, Nelson S.

J Immunol. 2001 Jan 1;166(1):458-65. doi: 10.4049/jimmunol.166.1.458. PMID: 11123324.

Lipopolysaccharide tolerance and ethanol modulate hepatic nitric oxide production in a gender-dependent manner.

Spitzer JA, Spitzer JJ.

Alcohol. 2000 May;21(1):27-35. doi: 10.1016/s0741-8329(99)00098-1. PMID: 10946155.

Acute alcohol intoxication and gadolinium chloride attenuate endotoxin-induced release of CC chemokines in the rat.

Bukara M, Bautista AP.

Alcohol. 2000 Feb;20(2):193-203. doi: 10.1016/s0741-8329(99)00100-7. PMID: 10719799.

Innate immunity and pulmonary host defense.

Zhang P, Summer WR, Bagby GJ, Nelson S.

Immunol Rev. 2000 Feb;173:39-51. doi: 10.1034/j.1600-065x.2000.917306.x. PMID: 10719666.

Serine/threonine phosphorylation in cellular signaling for alveolar macrophage phagocytic response to endotoxin.

Zhang P, Nelson S, Summer WR, Spitzer JA.

Shock. 2000 Jan;13(1):34-40. doi: 10.1097/00024382-200013010-00007. PMID: 10638667.

In vitro ethanol suppresses alveolar macrophage TNF-alpha during simian immunodeficiency virus infection.

Stoltz DA, Nelson S, Kolls JK, Zhang P, Bohm RP Jr, Murphey-Corb M, Bagby GJ.

Am J Respir Crit Care Med. 2000 Jan;161(1):135-40. doi: 10.1164/ajrccm.161.1.9905016. PMID: 10619810.

Pulmonary host defenses. Implications for therapy.

Mason CM, Nelson S.

Clin Chest Med. 1999 Sep;20(3):475-88, vii. doi: 10.1016/s0272-5231(05)70229-x. PMID: 10516897.

Effects of ethanol on neutrophil recruitment and lung host defense in nitric oxide synthase I and nitric oxide synthase II knockout mice.

Greenberg SS, Ouyang J, Zhao X, Parrish C, Nelson S, Giles TD.

Alcohol Clin Exp Res. 1999 Sep;23(9):1435-45. PMID: 10512307.

Activation of the superoxide-generating NADPH oxidase of intestinal lymphocytes produces highly reactive free radicals from sulfite.

Chamulitrat W.

Free Radic Biol Med. 1999 Aug;27(3-4):411-21. doi: 10.1016/s0891-5849(99)00088-x. PMID: 10468216.

Role of Kupffer cells in the ethanol-induced oxidative stress in the liver.

Bautista AP, Spitzer JJ.

Front Biosci. 1999 Jul 15;4:D589-95. doi: 10.2741/bautista. PMID: 10417056.

Differential regulation of inducible nitric oxide synthase gene expression by ethanol in the human intestinal epithelial cell line DLD-1.

Wang E, Spitzer JJ, Chamulitrat W.

Nitric Oxide. 1999 Jun;3(3):244-53. doi: 10.1006/niox.1999.0230. PMID: 10442856.

Granulocyte colony-stimulating factor modulates the pulmonary host response to endotoxin in the absence and presence of acute ethanol intoxication.

Zhang P, Bagby GJ, Stoltz DA, Summer WR, Nelson S.

J Infect Dis. 1999 Jun;179(6):1441-8. doi: 10.1086/314763. PMID: 10228066.

Ethanol suppression of the functional state of polymorphonuclear leukocytes obtained from uninfected and simian immunodeficiency virus infected rhesus macaques.

Stoltz DA, Zhang P, Nelson S, Bohm RP Jr, Murphey-Corb M, Bagby GJ.

Alcohol Clin Exp Res. 1999 May;23(5):878-84. PMID: 10371409.

Ethanol inhibits lung clearance of Pseudomonas aeruginosa by a neutrophil and nitric oxide-dependent mechanism, in vivo.

Greenberg SS, Zhao X, Hua L, Wang JF, Nelson S, Ouyang J.

Alcohol Clin Exp Res. 1999 Apr;23(4):735-44. PMID: 10235311.

Ethanol metabolism is not required for inhibition of LPS-stimulated transcription of inducible nitric oxide synthase.

Greenberg SS, Xie J, Ouyang J, Zhao X.

Alcohol. 1999 Apr;17(3):203-13. doi: 10.1016/s0741-8329(98)00048-2. PMID: 10231168.

Priming of Peyer's patch lymphoid cells by hemorrhagic shock and resuscitation to produce superoxide radical.

Chamulitrat W, Miller HI, McDonough KH.

Shock. 1999 Feb;11(2):136-42. doi: 10.1097/00024382-199902000-00011. PMID: 10030801.

Gender differences in some host defense mechanisms.

Spitzer JA.

Lupus. 1999;8(5):380-3. doi: 10.1177/096120339900800510. PMID: 10455517.

The human immunodeficiency virus type I Tat protein potentiates ethanol-induced neutrophil functional impairment in transgenic mice.

Prakash O, Zhang P, Xie M, Ali M, Zhou P, Coleman R, Stoltz DA, Bagby GJ, Shellito JE, Nelson S.

Alcohol Clin Exp Res. 1998 Dec;22(9):2043-9. PMID: 9884149.

Ethanol inhibits the potentiation of endotoxin by dibutyryl cAMP and 2-methylthio ATP in vivo.

Zhao X, Jie O, Li H, Xie J, Greenberg SS.

Alcohol Clin Exp Res. 1998 Nov;22(8):1662-72. PMID: 9835279.

Innate immunity, cytokines, and pulmonary host defense.

Nelson S, Summer WR.

Infect Dis Clin North Am. 1998 Sep;12(3):555-67, vii. doi: 10.1016/s0891-5520(05)70198-7. PMID: 9779378.

The potential mechanism of induction of inducible nitric oxide synthase mRNA in alveolar macrophages by lipopolysaccharide and its suppression by ethanol, in vivo.

Greenberg SS, Jie O, Zhao X, Wang JF, Giles TD.

Alcohol Clin Exp Res. 1998 Aug;22(5 Suppl):260S-265S. doi: 10.1097/00000374-199805001-00007. PMID: 9727648.

Simian immunodeficiency virus, infection, alcohol, and host defense.

Bagby GJ, Stoltz DA, Zhang P, Bohm RP Jr, Nelson S.

Alcohol Clin Exp Res. 1998 Aug;22(5 Suppl):193S-195S. doi: 10.1111/j.1530-0277.1998.tb03999.x. PMID: 9727633.

Role of PKC and tyrosine kinase in ethanol-mediated inhibition of LPS-inducible nitric oxide synthase.

Greenberg SS, Jie O, Zhao X, Wang JF.

Alcohol. 1998 Aug;16(2):167-75. doi: 10.1016/s0741-8329(97)00187-0. PMID: 9665319.

Modulation of the insulin-like growth factor system by chronic alcohol feeding.

Lang CH, Fan J, Lipton BP, Potter BJ, McDonough KH.

Alcohol Clin Exp Res. 1998 Jun;22(4):823-9. PMID: 9660307.

In vivo endotoxin enhances biliary ethanol-dependent free radical generation.

Chamulitrat W, Carnal J, Reed NM, Spitzer JJ.

Am J Physiol. 1998 Apr;274(4):G653-61. doi: 10.1152/ajpgi.1998.274.4.G653. PMID: 9575846.

Acute ethanol intoxication inhibits neutrophil beta2-integrin expression in rats during endotoxemia.

Zhang P, Bagby GJ, Xie M, Stoltz DA, Summer WR, Nelson S.

Alcohol Clin Exp Res. 1998 Feb;22(1):135-41. PMID: 9514298.

Enhancement of peritoneal leukocyte function by granulocyte colony-stimulating factor in rats with abdominal sepsis.

Zhang P, Bagby GJ, Stoltz DA, Summer WR, Nelson S.

Crit Care Med. 1998 Feb;26(2):315-21. doi: 10.1097/00003246-199802000-00035. PMID: 9468171.

Human and rat neutrophils constitutively express neural nitric oxide synthase mRNA.

Greenberg SS, Ouyang J, Zhao X, Giles TD.

Nitric Oxide. 1998;2(3):203-12. doi: 10.1006/niox.1998.0176. PMID: 9731638.

cAMP and purinergic P2y receptors upregulate and enhance inducible NO synthase mRNA and protein in vivo.

Greenberg SS, Zhao X, Wang JF, Hua L, Ouyang J.

Am J Physiol. 1997 Nov;273(5):L967-79. doi: 10.1152/ajplung.1997.273.5.L967. PMID: 9374723.

Intraportal lipopolysaccharide suppresses pulmonary antibacterial defense mechanisms.

Mason CM, Dobard E, Summer WR, Nelson S.

J Infect Dis. 1997 Nov;176(5):1293-302. doi: 10.1086/514125. PMID: 9359731.


Ethanol inhibits inducible nitric oxide synthase transcription and post-transcriptional processes in vivo.

Zhao X, Jie O, Li H, Xie J, Giles TD, Greenberg SS.

Alcohol Clin Exp Res. 1997 Oct;21(7):1246-56. PMID: 9347086.

Differential effects of L-N5-(1-iminoethyl)-ornithine on tone and endothelium-dependent vasodilator responses.

DeWitt BJ, Champion HC, Marrone JR, McNamara DB, Giles TD, Greenberg SS, Kadowitz PJ.

Am J Physiol. 1997 Sep;273(3 Pt 1):L588-94. doi: 10.1152/ajplung.1997.273.3.L588. PMID: 9316493.

Acute ethanol administration modulates leukocyte actin polymerization in endotoxic rats.

Zhang P, Spitzer JA.

Alcohol Clin Exp Res. 1997 Aug;21(5):779-83. PMID: 9267525.

Acute ethanol intoxication suppresses the pulmonary inflammatory response in rats challenged with intrapulmonary endotoxin.

Zhang P, Nelson S, Summer WR, Spitzer JA.

Alcohol Clin Exp Res. 1997 Aug;21(5):773-8. PMID: 9267524.

Interaction of ethanol with inducible nitric oxide synthase messenger RNA and protein: direct effects on autacoids and endotoxin in vivo.

Greenberg SS, Ouyang J, Zhao X, Xie J, Wang JF, Giles TD.

J Pharmacol Exp Ther. 1997 Aug;282(2):1044-54. PMID: 9262374.

Generation of nitro and superoxide radical anions from 2,4,6-trinitrobenzenesulfonic acid by rat gastrointestinal cells.

Chamulitrat W, Spitzer JJ.

Biochim Biophys Acta. 1997 Jul 19;1336(1):73-82. doi: 10.1016/s0304-4165(97)00012-3. PMID: 9271252.

Dissociation of TNF-alpha from endotoxin-induced nitric oxide and acute-phase hypotension.

Xie J, Joseph KO, Bagby GJ, Giles TD, Greenberg SS.

Am J Physiol. 1997 Jul;273(1 Pt 2):H164-74. doi: 10.1152/ajpheart.1997.273.1.H164. PMID: 9249487.

Ceramide inhibits nitric oxide production in alveolar macrophages of endotoxin and ethanol plus endotoxin-treated rats.

Spitzer JA.

Biochem Biophys Res Commun. 1997 May 29;234(3):738-41. doi: 10.1006/bbrc.1997.6691. PMID: 9175785.

Keratinocyte growth factor increases transalveolar sodium reabsorption in normal and injured rat lungs.

Guery BP, Mason CM, Dobard EP, Beaucaire G, Summer WR, Nelson S.

Am J Respir Crit Care Med. 1997 May;155(5):1777-84. doi: 10.1164/ajrccm.155.5.9154891. PMID: 9154891.

Modulation of the lung host response by granulocyte colony-stimulating factor in rats challenged with intrapulmonary endotoxin.

Zhang P, Bagby GJ, Stoltz DA, Spitzer JA, Summer WR, Nelson S.

Shock. 1997 Mar;7(3):193-9. doi: 10.1097/00024382-199703000-00007. PMID: 9068085.

Gender differences in nitric oxide production by alveolar macrophages in ethanol plus lipopolysaccharide-treated rats.

Spitzer JA.

Nitric Oxide. 1997 Feb;1(1):31-8. doi: 10.1006/niox.1996.0101. PMID: 9701042.

Effects of female hormones (17beta-estradiol and progesterone) on nitric oxide production by alveolar macrophages in rats.

Robert R, Spitzer JA.

Nitric Oxide. 1997;1(6):453-62. doi: 10.1006/niox.1997.0157. PMID: 9466950.

Alcohol-induced thymocyte apoptosis is accompanied by impaired mitochondrial function.

Wang JF, Spitzer JJ.

Alcohol. 1997 Jan-Feb;14(1):99-105. doi: 10.1016/s0741-8329(97)86148-4. PMID: 9014030.

Protein tyrosine kinase activity and the influence of gender in phagocytosis and tumor necrosis factor secretion in alveolar macrophages and lung-recruited neutrophils.

Spitzer JA, Zhang P.

Shock. 1996 Dec;6(6):426-33. doi: 10.1097/00024382-199612000-00007. PMID: 8961393.

Time to resolution of morbidity: an endpoint for assessing the clinical cure of community-acquired pneumonia.

Daifuku R, Movahhed H, Fotheringham N, Bear MB, Nelson S.

Respir Med. 1996 Nov;90(10):587-92. doi: 10.1016/s0954-6111(96)90016-5. PMID: 8959115.

Cross-tolerance between acute alcohol intoxication and endotoxemia.

Bautista AP, Spitzer JJ.

Alcohol Clin Exp Res. 1996 Nov;20(8):1395-400. doi: 10.1111/j.1530-0277.1996.tb01139.x. PMID: 8947315.

An in vivo cytokine and endotoxin-independent pathway for induction of nitric oxide synthase II mRNA, enzyme, and nitrate/nitrite in alveolar macrophages.

Greenberg SS, Xie J, Zhao X, Jie O, Giles TD.

Biochem Biophys Res Commun. 1996 Oct 3;227(1):160-7. doi: 10.1006/bbrc.1996.1483. PMID: 8858119.

Ethanol suppresses endotoxin but not platelet activating factor-induced hypotension and nitric oxide.

Greenberg SS, Xie J, Powers DR, Giles TD.

Alcohol Clin Exp Res. 1996 Oct;20(7):1260-8. doi: 10.1111/j.1530-0277.1996.tb01121.x. PMID: 8904980.

Nitric oxide and liver injury in alcohol-fed rats after lipopolysaccharide administration.

Chamulitrat W, Spitzer JJ.

Alcohol Clin Exp Res. 1996 Sep;20(6):1065-70. doi: 10.1111/j.1530-0277.1996.tb01947.x. PMID: 8892528.

Chronic alcohol feeding in liquid diet or in drinking water has similar effects on electron microscopic appearance of the hepatic sinusoid in the rat.

Sarphie TG, D'Souza NB, Spitzer JJ, Deaciuc IV.

Alcohol Clin Exp Res. 1996 Sep;20(6):973-9. doi: 10.1111/j.1530-0277.1996.tb01933.x. PMID: 8892514.

Gender differences in phagocytic responses in the blood and liver, and the generation of cytokine-induced neutrophil chemoattractant in the liver of acutely ethanol-intoxicated rats.

Spitzer JA, Zhang P.

Alcohol Clin Exp Res. 1996 Aug;20(5):914-20. doi: 10.1111/j.1530-0277.1996.tb05271.x. PMID: 8865968.

Hepatic sinusoidal endothelial cell in alcoholemia and endotoxemia.

Deaciuc IV, Spitzer JJ.

Alcohol Clin Exp Res. 1996 Jun;20(4):607-14. doi: 10.1111/j.1530-0277.1996.tb01662.x. PMID: 8800375.

Granulocyte colony-stimulating factor and modulation of inflammatory cells in sepsis.

Nelson S, Bagby GJ.

Clin Chest Med. 1996 Jun;17(2):319-32. doi: 10.1016/s0272-5231(05)70317-8. PMID: 8792069.

Keratinocyte growth factor attenuates lung leak induced by alpha-naphthylthiourea in rats.

Mason CM, Guery BP, Summer WR, Nelson S.

Crit Care Med. 1996 Jun;24(6):925-31. doi: 10.1097/00003246-199606000-00009. PMID: 8681593.

Postbinge effects of acute alcohol intoxication on hepatic free radical formation.

Bautista AP, Spitzer JJ.

Alcohol Clin Exp Res. 1996 May;20(3):502-9. doi: 10.1111/j.1530-0277.1996.tb01083.x. PMID: 8727245.

Endotoxin-induced oxidative stress in the rat small intestine: role of nitric oxide.

Chamulitrat W, Skrepnik NV, Spitzer JJ.

Shock. 1996 Mar;5(3):217-22. doi: 10.1097/00024382-199603000-00009. PMID: 8696987.

Alcohol modulates alveolar macrophage tumor necrosis factor-alpha, superoxide anion, and nitric oxide secretion in the rat.

D'Souza NB, Nelson S, Summer WR, Deaciuc IV.

Alcohol Clin Exp Res. 1996 Feb;20(1):156-63. doi: 10.1111/j.1530-0277.1996.tb01059.x. PMID: 8651446.

Decreased production of reactive oxygen intermediates is an early event during in vitro apoptosis of rat thymocytes.

Wang JF, Jerrells TR, Spitzer JJ.

Free Radic Biol Med. 1996;20(4):533-42. doi: 10.1016/0891-5849(95)02085-3. PMID: 8904294.

Alcohol ingestion impairs host defenses predisposing otherwise healthy mice to Pneumocystis carinii infection.

D'Souza NB, Mandujano JF, Nelson S, Summer WR, Shellito JE.

Alcohol Clin Exp Res. 1995 Oct;19(5):1219-25. doi: 10.1111/j.1530-0277.1995.tb01604.x. PMID: 8561294.

Differential effects of in vivo ethanol on LPS-induced TNF and nitric oxide production in the lung.

Kolls JK, Xie J, Lei D, Greenberg S, Summer WR, Nelson S.

Am J Physiol. 1995 Jun;268(6 Pt 1):L991-8. doi: 10.1152/ajplung.1995.268.6.L991. PMID: 7541951.

Pathogenesis and host defense in pulmonary infections.

Mason CM, Kolls JK, Nelson S.

Curr Opin Pulm Med. 1995 May;1(3):163-70. PMID: 9363048.

Rapid induction of mRNA for nitric oxide synthase II in rat alveolar macrophages by intratracheal administration of Mycobacterium tuberculosis and Mycobacterium avium.

Greenberg SS, Xie J, Kolls J, Mason C, Didier P.

Proc Soc Exp Biol Med. 1995 May;209(1):46-53. doi: 10.3181/00379727-209-43876. PMID: 7536940.

Granulocyte-macrophage colony stimulating factor and Pneumocystis carinii pneumonia in mice.

Mandujano JF, D'Souza NB, Nelson S, Summer WR, Beckerman RC, Shellito JE.

Am J Respir Crit Care Med. 1995 Apr;151(4):1233-8. doi: 10.1164/ajrccm/151.4.1233. PMID: 7697258.

Tumor necrosis factor-alpha cell-surface receptors of liver parenchymal and nonparenchymal cells during acute and chronic alcohol administration to rats.

Deaciuc IV, D'Souza NB, Spitzer JJ.

Alcohol Clin Exp Res. 1995 Apr;19(2):332-8. doi: 10.1111/j.1530-0277.1995.tb01511.x. PMID: 7625565.

Liver sinusoid during chronic alcohol consumption in the rat: an electron microscopic study.

Sarphie TG, Deaciuc IV, Spitzer JJ, D'Souza NB.

Alcohol Clin Exp Res. 1995 Apr;19(2):291-8. doi: 10.1111/j.1530-0277.1995.tb01505.x. PMID: 7625560.

Ethanol suppresses Mycobacteria tuberculosis-induced mRNA for nitric oxide synthase in alveolar macrophages, in vivo.

Greenberg S, Xie J, Kolls J, Nelson S, Didier P, Mason C.

Alcohol Clin Exp Res. 1995 Apr;19(2):394-401. doi: 10.1111/j.1530-0277.1995.tb01521.x. PMID: 7542849.

Chronic alcohol administration stimulates nitric oxide formation in the rat liver with or without pretreatment by lipopolysaccharide.

Wang JF, Greenberg SS, Spitzer JJ.

Alcohol Clin Exp Res. 1995 Apr;19(2):387-93. doi: 10.1111/j.1530-0277.1995.tb01520.x. PMID: 7542848.

Ethanol-induced depletion of lymphocytes from the mesenteric lymph nodes of C57B1/6 mice is associated with RNA but not DNA degradation.

Sibley DA, Fuseler J, Slukvin I, Jerrells TR.

Alcohol Clin Exp Res. 1995 Apr;19(2):324-31. doi: 10.1111/j.1530-0277.1995.tb01510.x. PMID: 7542847.

Pathophysiology of pneumonia.

Nelson S, Mason CM, Kolls J, Summer WR.

Clin Chest Med. 1995 Mar;16(1):1-12. PMID: 7768083.

Alcohol, tumor necrosis factor, and tuberculosis.

Nelson S, Mason C, Bagby G, Summer W.

Alcohol Clin Exp Res. 1995 Feb;19(1):17-24. doi: 10.1111/j.1530-0277.1995.tb01467.x. PMID: 7771645.

Independent suppression of nitric oxide and TNF alpha in the lung of conscious rats by ethanol.

Xie J, Kolls J, Bagby G, Greenberg SS.

FASEB J. 1995 Feb;9(2):253-61. doi: 10.1096/fasebj.9.2.7540157. PMID: 7540157.

Effects of ethanol on cellular immunity to facultative intracellular bacteria.

Jerrells TR, Sibley D.

Alcohol Clin Exp Res. 1995 Feb;19(1):11-6. doi: 10.1111/j.1530-0277.1995.tb01466.x. PMID: 7539599.

Nitro containing L-arginine analogs interfere with assays for nitrate and nitrite.

Greenberg SS, Xie J, Spitzer JJ, Wang JF, Lancaster J, Grisham MB, Powers DR, Giles TD.

Life Sci. 1995;57(21):1949-61. doi: 10.1016/0024-3205(95)02181-h. PMID: 7475944.

Ethanol suppresses LPS-induced mRNA for nitric oxide synthase II in alveolar macrophages in vivo and in vitro.

Greenberg SS, Xie J, Wang Y, Kolls J, Malinski T, Summer WR, Nelson S.

Alcohol. 1994 Nov-Dec;11(6):539-47. doi: 10.1016/0741-8329(94)90081-7. PMID: 7532415.

Increased susceptibility of experimental animals to infectious organisms as a consequence of ethanol consumption.

Jerrells TR, Slukvin I, Sibley D, Fuseler J.

Alcohol Alcohol Suppl. 1994;2:425-30. PMID: 8974364.